Keto Research Papers

Pinned Articles

Title (click on the titles below to access to the paper) Author Trials Publisher Articles
Optimal clinical management of children receiving dietary therapies for epilepsy: Updated recommendations of the International Ketogenic Diet Study Group.  Eric H. Kossoff, Beth A. Zupec-Kania, Stephane Auvin, Karen R. Ballaban-Gil, A.G. Christina Bergqvist, Robyn Blackford, Jeffrey R. Buchhalter, Roberto H. Caraballo, J. Helen Cross, Maria G. Dahlin, Elizabeth J. Donner, Orkide Guzel, Rana S. Jehle, Joerg Klepper, Hoon-Chul Kang, Danielle A. Lambrechts, Y.M. Christiana Liu, Janak K. Nathan, Douglas R. Nordli Jr, Heidi H. Pfeifer, Jong M. Rho, Ingrid E. Scheffer, Suvasini Sharma, Carl E. Stafstrom, Elizabeth A. Thiele, Zahava Turner, Maria M. Vaccarezza, Elles J.T.M. van der Louw, Pierangelo Veggiotti, James W. Wheless, Elaine C. Wirrell, The Charlie Foundation, Matthew’s Friends, and the Practice Committee of the Child Neurology Society Epilepsia Open, 3(2):175–192, 2018doi: 10.1002/epi4.12225 https://onlinelibrary.wiley.com/doi/epdf/10.1002/epi4.12225
Glut1 Deficiency Syndrome (Glut1DS): State of the art in 2020 and recommendations of the international Glut1DS study group Joerg Klepper1 | Cigdem Akman2 | Marisa Armeno3 | Stéphane Auvin4 | Mackenzie Cervenka5 | Helen J. Cross6 | Valentina De Giorgis7 | Adela Della Marina8 | Kristin Engelstad2 | Nicole Heussinger9 | Eric H. Kossoff10 | Wilhelmina G. Leen11 | Baerbel Leiendecker8 | Umrao R. Monani12 | Hirokazu Oguni13 | Elizabeth Neal14 | Juan M. Pascual15 | Toni S. Pearson16 | Roser Pons17 | Ingrid E. Scheffer18 | Pierangelo Veggiotti19 | Michél Willemsen20 | Sameer M. Zuberi21 | Darryl C. De Vivo2 Epilepsia Open 2018;3(2):175–92 Wiley Periodicals LLC on behalf of International League Against Epilepsy https://onlinelibrary.wiley.com/doi/epdf/10.1002/epi4.12414
What are the minimum requirements for ketogenic diet services in resource-limited regions? Recommendations from the International League Against Epilepsy Task Force for Dietary Therapy *Eric H. Kossoff, †Nabil Al-Macki, *Mackenzie C. Cervenka, ‡Heung D. Kim, §Jianxiang Liao, ¶Katherine Megaw, #Janak K. Nathan, **Ximena Raimann, ††Rocio Rivera, ‡‡Adelheid Wiemer-Kruel, §§Emma Williams, and ¶¶Beth A. Zupec-Kania Epilepsia, **(*):1–6, 2015 doi: 10.1111/epi.13039 https://epi-care.eu/wp-content/uploads/2020/03/Keto-Minimum-Requirements-ILAE.pdf
International Recommendations for the Management of Adults Treated with Ketogenic Diet Therapies is a consensus paper that has been published by an expert group of practitioners that manage ketogenic dietary therapies for adults around the world.  The full paper does have to be purchased at this time for $39 but we hope that in time it will become freely available.  The link to gain access to the abstract and buy the paper is as follows: https://cp.neurology.org/content/early/2020/10/28/CPJ.0000000000001007

20th September 2022

Title (click on the titles below to access to the paper) Author Trials Publisher

 Ketogenic diet attenuates post-cardiac arrest brain injury by upregulation of pentose phosphate pathway-mediated antioxidant defense in a mouse model of cardiac arrest. 

Peng F, Zhang YH, Zhang L, Yang M, Chen C, Yu H, Li T.

Nutrition. 2022 Aug 12;103-104:111814. doi: 10.1016/j.nut.2022.111814. Online ahead of print.

PMID: 36116157

College students’ perceptions of individuals following popular diets and individuals with Orthorexia Nervosa. 

Weinstock M, Mazzeo SE.

Eat Behav. 2022 Sep 9;47:101671. doi: 10.1016/j.eatbeh.2022.101671. Online ahead of print. PMID: 36113227

 Ketogenic diet uncovers differential metabolic plasticity of brain cells. 

Düking T, Spieth L, Berghoff SA, Piepkorn L, Schmidke AM, Mitkovski M, Kannaiyan N, Hosang L, Scholz P, Shaib AH, Schneider LV, Hesse D, Ruhwedel T, Sun T, Linhoff L, Trevisiol A, Köhler S, Pastor AM, Misgeld T, Sereda M, Hassouna I, Rossner MJ, Odoardi F, Ischebeck T, de Hoz L, Hirrlinger J, Jahn O, Saher G.

Sci Adv. 2022 Sep 16;8(37):eabo7639. doi: 10.1126/sciadv.abo7639. Epub 2022 Sep 16.

PMID: 36112685
 Effect of Ketogenic Diets on Cardio-Metabolic Outcomes in Cancer Patients: A Systematic Review and Meta-Analysis of Controlled Clinical Trials. 

Amanollahi A, Khazdouz M, Malekahmadi M, Klement RJ, Lee D, Khodabakhshi A.

Nutr Cancer. 2022 Sep 15:1-17. doi: 10.1080/01635581.2022.2117388. Online ahead of print.

PMID: 36110060

Cost effectiveness of telehealth-delivered exercise and dietary weight loss programs for knee osteoarthritis within a 12-month randomised trial. 

Harris A, Hinman RS, Lawford BJ, Egerton T, Keating C, Brown C, Metcalf B, Spiers L, Sumithran P, Quicke JG, Bennell KL.

Arthritis Care Res (Hoboken). 2022 Sep 15. doi: 10.1002/acr.25022. Online ahead of print.

PMID: 36106928
The Anti-Inflammatory Effect of Preventive Intervention with Ketogenic Diet Mediated by the Histone Acetylation of mGluR5 Promotor Region in Rat Parkinson’s Disease Model: A Dual-Tracer PET Study. 

Zhu Y, Tang X, Cheng Z, Dong Q, Ruan G.

Parkinsons Dis. 2022 Sep 5;2022:3506213. doi: 10.1155/2022/3506213. eCollection 2022.

PMID: 36105302 Free PMC article.
Efficacy, retention rate and influencing factors of ketogenic diet therapy in children with refractory epilepsy: a retrospective study. 

Shen J, Jiang T, Gao F, Jiang K.

Neuropediatrics. 2022 Sep 13. doi: 10.1055/a-1942-2447. Online ahead of print.

PMID: 36100257
The Effects of Medium-Chain Triglyceride Oil Supplementation on Endurance Performance and Substrate Utilization in Healthy Populations: A Systematic Review. 

Chapman-Lopez TJ, Koh Y.

J Obes Metab Syndr. 2022 Sep 13. doi: 10.7570/jomes22028. Online ahead of print.

PMID: 36096496 Review.
Severe type 2 diabetes (T2D) remission using a very low-calorie ketogenic diet (VLCKD). 

Correa LL, Medeiros de Sousa PA, Dinis L, Carloto LB, Nuñez-Garcia M, Sajoux I, Senhorini S.

Endocrinol Diabetes Metab Case Rep. 2022 Sep 1;2022:22-0295. doi: 10.1530/EDM-22-0295. Online ahead of print.

PMID: 36094136
Pharmacological and non-pharmacological therapeutic interventions for the treatment of spinal cord injury-induced pain. 

Eller OC, Willits AB, Young EE, Baumbauer KM.

Front Pain Res (Lausanne). 2022 Aug 24;3:991736. doi: 10.3389/fpain.2022.991736. eCollection 2022.

PMID: 36093389 Free PMC article. Review.
Let food be thy medicine: the role of diet in colorectal cancer: a narrative review. 

Zheng Y, Meng L, Liu H, Sun L, Nie Y, Wu Q, Fan D, Li M.

J Gastrointest Oncol. 2022 Aug;13(4):2020-2032. doi: 10.21037/jgo-22-32.

PMID: 36092326 Free PMC article. Review.
Case report: Novel SCN4A variant associated with a severe congenital myasthenic syndrome/myopathy phenotype. 

Berghold VM, Koko M, Berutti R, Plecko B.

Front Pediatr. 2022 Aug 26;10:944784. doi: 10.3389/fped.2022.944784. eCollection 2022.

PMID: 36090556 Free PMC article.

The Effect of Ketogenic Diet on Shared Risk Factors of Cardiovascular Disease and Cancer. 

Mohammadifard N, Haghighatdoost F, Rahimlou M, Rodrigues APS, Gaskarei MK, Okhovat P, de Oliveira C, Silveira EA, Sarrafzadegan N.

Nutrients. 2022 Aug 25;14(17):3499. doi: 10.3390/nu14173499.

PMID: 36079756 Free PMC article. Review.

The ketogenic diet prevents steatosis and insulin resistance by reducing lipogenesis, diacylglycerol accumulation and protein kinase C activity in male rat liver. 

Jani S, Da Eira D, Stefanovic M, Ceddia RB.

J Physiol. 2022 Sep;600(18):4137-4151. doi: 10.1113/JP283552. Epub 2022 Sep 4.

PMID: 35974660

Ketogenic diet, epilepsy and cognition: what do we know so far? A systematic review. 

Lima MC, Gabiatti MP, Moreira JD, Ribeiro LC, Lunardi MDS, Lin K, Venske DK.

Nutr Rev. 2022 Sep 5;80(10):2064-2075. doi: 10.1093/nutrit/nuac021.

PMID: 35535020

12th September 2022

Title (click on the titles below to access to the paper) Author Trials Publisher
Ruminal fermentation and methane production in vitro, milk production, nutrient utilization, blood profile, and immune responses of lactating goats fed polyphenolic and saponin-rich plant extracts.  Shilwant S, Hundal JS, Singla M, Patra AK. Environ Sci Pollut Res Int. 2022 Sep 10. doi: 10.1007/s11356-022-22931-y. Online ahead of print. PMID: 36087183
Ketogenic diet induced weight loss occurs independent of housing temperature and is followed by hyperphagia and weight regain after cessation in mice.  Weber A, Medak KD, Townsend LK, Wright DC. J Physiol. 2022 Sep 9. doi: 10.1113/JP283469. Online ahead of print. PMID: 36083198
A rare case of hypomyelinating leukodystrophy-14 benefiting from ketogenic diet therapy.  Ünalp A, Köse M, Karaoğlu P, Güzin Y, Yılmaz Ü. Turk J Pediatr. 2022;64(4):747-753. doi: 10.24953/turkjped.2021.1662. PMID: 36082649
Ketogenic Diet for Preoperative Weight Reduction in Bariatric Surgery: A Narrative Review.  Colangeli L, Gentileschi P, Sbraccia P, Guglielmi V. Nutrients. 2022 Aug 31;14(17):3610. doi: 10.3390/nu14173610. PMID: 36079867 Review.
 Ketogenic Diet Treatment of Defects in the Mitochondrial Malate Aspartate Shuttle and Pyruvate Carrier.  Bölsterli BK, Boltshauser E, Palmieri L, Spenger J, Brunner-Krainz M, Distelmaier F, Freisinger P, Geis T, Gropman AL, Häberle J, Hentschel J, Jeandidier B, Karall D, Keren B, Klabunde-Cherwon A, Konstantopoulou V, Kottke R, Lasorsa FM, Makowski C, Mignot C, O’Gorman Tuura R, Porcelli V, Santer R, Sen K, Steinbrücker K, Syrbe S, Wagner M, Ziegler A, Zöggeler T, Mayr JA, Prokisch H, Wortmann SB. Nutrients. 2022 Aug 31;14(17):3605. doi: 10.3390/nu14173605. PMID: 36079864
Ketogenic Diet: A Dietary Intervention via Gut Microbiome Modulation for the Treatment of Neurological and Nutritional Disorders (a Narrative Review).  Lim JM, Letchumanan V, Tan LT, Hong KW, Wong SH, Ab Mutalib NS, Lee LH, Law JW. Nutrients. 2022 Aug 30;14(17):3566. doi: 10.3390/nu14173566. PMID: 36079829 Review.
Insulin-Lowering Diets in Metastatic Cancer.  Shen S, Iyengar NM. Nutrients. 2022 Aug 27;14(17):3542. doi: 10.3390/nu14173542. PMID: 36079800 Review.
The Effect of Ketogenic Diet on Shared Risk Factors of Cardiovascular Disease and Cancer.  Mohammadifard N, Haghighatdoost F, Rahimlou M, Rodrigues APS, Gaskarei MK, Okhovat P, de Oliveira C, Silveira EA, Sarrafzadegan N. Nutrients. 2022 Aug 25;14(17):3499. doi: 10.3390/nu14173499. PMID: 36079756 Review.
Migraine Prevention through Ketogenic Diet: More than Body Mass Composition Changes.  Valente M, Garbo R, Filippi F, Antonutti A, Ceccarini V, Tereshko Y, Di Lorenzo C, Gigli GL. J Clin Med. 2022 Aug 23;11(17):4946. doi: 10.3390/jcm11174946. PMID: 36078876
Curcumin Remedies Testicular Function and Spermatogenesis in Male Mice with Low-Carbohydrate-Diet-Induced Metabolic Dysfunction.  Tsao CW, Ke PS, Yang HY, Chang TC, Liu CY. Int J Mol Sci. 2022 Sep 2;23(17):10009. doi: 10.3390/ijms231710009. PMID: 36077406
Effects of anti-seizure therapies on sleep in patients with epilepsy: A literature review.  Ye L, Xu J, Chen C, Zhang L, Wang S. Acta Neurol Scand. 2022 Sep 7. doi: 10.1111/ane.13699. Online ahead of print. PMID: 36071677 Review.
Very low carbohydrate (ketogenic) diets in type 2 diabetes: A systematic review and meta-analysis of randomized controlled trials.  Parry-Strong A, Wright-McNaughton M, Weatherall M, Hall RM, Coppell KJ, Barthow C, Krebs JD. Diabetes Obes Metab. 2022 Aug 15. doi: 10.1111/dom.14837. Online ahead of print. PMID: 36064937
Prader-Willi Syndrome in Adults: An Update On Nutritional Treatment and Pharmacological Approach.  Barrea L, Vetrani C, Fintini D, de Alteriis G, Panfili FM, Bocchini S, Verde L, Colao A, Savastano S, Muscogiuri G. Curr Obes Rep. 2022 Sep 5. doi: 10.1007/s13679-022-00478-w. Online ahead of print. PMID: 36063285 Review.
Current Evidence Concerning Effects of Ketogenic Diet and Intermittent Fasting in Patients with Nonalcoholic Fatty Liver.  Sripongpun P, Churuangsuk C, Bunchorntavakul C. J Clin Transl Hepatol. 2022 Aug 28;10(4):730-739. doi: 10.14218/JCTH.2021.00494. Epub 2022 May 6. PMID: 36062288 Free PMC article. Review.
Gut microbiota and host genetics modulate the effect of diverse diet patterns on metabolic health.  Huda MN, Salvador AC, Barrington WT, Gacasan CA, D’Souza EM, Deus Ramirez L, Threadgill DW, Bennett BJ. Front Nutr. 2022 Aug 18;9:896348. doi: 10.3389/fnut.2022.896348. eCollection 2022. PMID: 36061898 Free PMC article.
Metabolic management of microenvironment acidity in glioblastoma.  Seyfried TN, Arismendi-Morillo G, Zuccoli G, Lee DC, Duraj T, Elsakka AM, Maroon JC, Mukherjee P, Ta L, Shelton L, D’Agostino D, Kiebish M, Chinopoulos C. Front Oncol. 2022 Aug 17;12:968351. doi: 10.3389/fonc.2022.968351. eCollection 2022. PMID: 36059707 Free PMC article. Review.
Restricted Ketogenic Diet Therapy for Primary Lung Cancer With Metastasis to the Brain: A Case Report.  Evangeliou AE, Spilioti MG, Vassilakou D, Goutsaridou F, Seyfried TN. Cureus. 2022 Aug 2;14(8):e27603. doi: 10.7759/cureus.27603. eCollection 2022 Aug. PMID: 36059366 Free PMC article.
Is there a place for dietetic interventions in adult ADHD?  Breda V, Cerqueira RO, Ceolin G, Koning E, Fabe J, McDonald A, Gomes FA, Brietzke E. Prog Neuropsychopharmacol Biol Psychiatry. 2022 Dec 20;119:110613. doi: 10.1016/j.pnpbp.2022.110613. Epub 2022 Aug 12. PMID: 35964708 Review.
Ameliorating effect of ketogenic diet on acute status epilepticus: Insights into biochemical and histological changes in rat hippocampus.  Shehata NI, Abdelsamad MA, Amin HAA, Sadik NAH, Shaheen AA. J Food Biochem. 2022 Sep;46(9):e14217. doi: 10.1111/jfbc.14217. Epub 2022 May 11. PMID: 35543175  |

5th September 2022

Title (click on the titles below to access to the paper) Author Trials Publisher
[Tuberous sclerosis complex: diagnosis and current treatment].  Cerisola A, Cibils L, Chaibún ME, Pedemonte V, Rosas M. Medicina (B Aires). 2022 Aug 30;82 Suppl 3:71-75. PMID: 36054862 Spanish.
The Genetic Landscape of Complex Childhood-Onset Hyperkinetic Movement Disorders.  Pérez-Dueñas B, Gorman K, Marcé-Grau A, Ortigoza-Escobar JD, Macaya A, Danti FR, Barwick K, Papandreou A, Ng J, Meyer E, Mohammad SS, Smith M, Muntoni F, Munot P, Uusimaa J, Vieira P, Sheridan E, Guerrini R, Cobben J, Yilmaz S, De Grandis E, Dale RC, Pons R, Peall KJ, Leuzzi V, Kurian MA. Mov Disord. 2022 Aug 25. doi: 10.1002/mds.29182. Online ahead of print. PMID: 36054588
Nutrients and amyloid β status in the brain: A narrative review.  Díaz G, Lengele L, Sourdet S, Soriano G, de Souto Barreto P. Ageing Res Rev. 2022 Aug 30;81:101728. doi: 10.1016/j.arr.2022.101728. Online ahead of print. PMID: 36049590 Review.
Ketogenic diet: an effective treatment approach for neurodegenerative diseases.  Tao Y, Leng SX, Zhang H. Curr Neuropharmacol. 2022 Aug 30. doi: 10.2174/1570159X20666220830102628. Online ahead of print. PMID: 36043794
[Nutritional factors associated with migraine].  Hernando-Requejo V, Juárez-Torrejón N, Huertas-González N. Nutr Hosp. 2022 Sep 1;39(Spec No3):69-73. doi: 10.20960/nh.04316.  PMID: 36039985 Spanish.
Effects of the ketogenic diet in mice with hind limb ischemia.  Shalamu A, Dong Z, Liu B, Pan L, Cai Y, Liu L, Ma X, Hu K, Sun A, Ge J. Nutr Metab (Lond). 2022 Aug 29;19(1):59. doi: 10.1186/s12986-022-00695-z. PMID: 36038886 Free PMC article.
Interventions for ADHD in children & adolescents with epilepsy: A review and decision tree to guide clinicians.  Ono KE, Bearden DJ, Lee SM, Moss C, Kheder A, Cernokova I, Drane DL, Gedela S. Epilepsy Behav. 2022 Aug 26;135:108872. doi: 10.1016/j.yebeh.2022.108872. Online ahead of print. PMID: 36037580 Review.
Profound Elevation in LDL Cholesterol Level Following a Ketogenic Diet: A Case Series.  Crosier R, McPherson R. CJC Open. 2022 Jun 9;4(8):732-734. doi: 10.1016/j.cjco.2022.05.001. eCollection 2022 Aug. PMID: 36035741 Free PMC article.
 A Review of Ketogenic Diet and Lifestyle.  McGaugh E, Barthel B. Mo Med. 2022 Jan-Feb;119(1):84-88. PMID: 36033148 Free PMC article. Review.

29th August 2022

Title (click on the titles below to access to the paper) Author Trials Publisher
Nutrition as Personalized Medicine against SARS-CoV-2 Infections: Clinical and Oncological Options with a Specific Female Groups Overview.  Dellino M, Cascardi E, Vinciguerra M, Lamanna B, Malvasi A, Scacco S, Acquaviva S, Pinto V, Di Vagno G, Cormio G, De Luca R, Lafranceschina M, Cazzato G, Ingravallo G, Maiorano E, Resta L, Daniele A, La Forgia D. Int J Mol Sci. 2022 Aug 15;23(16):9136. doi: 10.3390/ijms23169136. PMID: 36012402 Free PMC article. Review.
Ketogenic Diet Benefits to Weight Loss, Glycemic Control, and Lipid Profiles in Overweight Patients with Type 2 Diabetes Mellitus: A Meta-Analysis of Randomized Controlled Trails.  Zhou C, Wang M, Liang J, He G, Chen N. Int J Environ Res Public Health. 2022 Aug 22;19(16):10429. doi: 10.3390/ijerph191610429. PMID: 36012064 Free PMC article. Review.
Perceptions and Experiences of Nutrition Interventions in Individuals with Amyotrophic Lateral Sclerosis (ALS) and their Caregivers.  Guillemin L BSc, RD, Hofstede J BSc, RD, Anderson T BSc, RD, Walkeden H BSc, RD, Schellenberg K MD, MMedEd, FRCPC, CSCN (EMG), Kang E MSc, RD, Berry D BSc, RD, Lefebvre S BSc, RD, Lieffers JR PhD, RD. Can J Diet Pract Res. 2022 Aug 25:1-5. doi: 10.3148/cjdpr-2022-014. Online ahead of print. PMID: 36004737
Adjuvant Treatment for Protocadherin 19 (PCDH19) Syndrome.  Moncayo JA, Vargas MN, Castillo I, Granda PV, Duque AM, Argudo JM, Matcheswalla S, Lopez Dominguez GE, Monteros G, Andrade AF, Ojeda D, Yepez M. Cureus. 2022 Jul 22;14(7):e27154. doi: 10.7759/cureus.27154. eCollection 2022 Jul. PMID: 36004035 Free PMC article. Review.
Nutritional aspects in chronic non-cancer pain: A systematic review.  Xu Lou I, Gil-García E, Cáceres-Matos R, Ali K, Molina E. Front Nutr. 2022 Aug 8;9:931090. doi: 10.3389/fnut.2022.931090. eCollection 2022. PMID: 36003834 Free PMC article.
Phase angle as biomarker of inflammatory changes during very low-calorie ketogenic diet.  Barrea L, Muscogiuri G, Savastano S. Int J Obes (Lond). 2022 Aug 24. doi: 10.1038/s41366-022-01201-4. Online ahead of print. PMID: 36002514 No abstract available.
Progress of clinical research studies on tuberous sclerosis complex-related epilepsy in China.  Liu T, Chen F, Zhai F, Liang S. Acta Neurol Scand. 2022 Aug 24. doi: 10.1111/ane.13692. Online ahead of print. PMID: 36000491 Review.
A Novel Multiphase Modified Ketogenic Diet: An Effective and Safe Tool for Weight Loss in Chinese Obese Patients.  Wu W, Zhou Q, Yuan P, Qiao D, Deng S, Cheng H, Ren Y. Diabetes Metab Syndr Obes. 2022 Aug 17;15:2521-2534. doi: 10.2147/DMSO.S365192. eCollection 2022. PMID: 35999869 Free PMC article. Clinical Trial.
Effects of the ketogenic diet therapy in patients with STXBP1-related encephalopathy.  Nam JY, Teng LY, Cho K, Kang HC, Lee JS, Kim HD, Kim SH. Epilepsy Res. 2022 Aug 1;186:106993. doi: 10.1016/j.eplepsyres.2022.106993. Online ahead of print. PMID: 35998430
Ketogenic diet and ketamine infusion treatment to target chronic persistent eating disorder psychopathology in anorexia nervosa: a pilot study.  Calabrese L, Scolnick B, Zupec-Kania B, Beckwith C, Costello K, Frank GKW. Eat Weight Disord. 2022 Aug 23. doi: 10.1007/s40519-022-01455-x. Online ahead of print. PMID: 35997954
International consensus recommendations for management of New Onset Refractory Status Epilepticus (NORSE) incl. Febrile Infection-Related Epilepsy Syndrome (FIRES): Statements and Supporting Evidence.  Wickstrom R, Taraschenko O, Dilena R, Payne ET, Specchio N, Nabbout R, Koh S, Gaspard N, Hirsch LJ; International NORSE Consensus Group. Epilepsia. 2022 Aug 23. doi: 10.1111/epi.17397. Online ahead of print. PMID: 35997591
Ketogenic diet administration to mice after a high-fat-diet regimen promotes weight loss, glycemic normalization and induces adaptations of ketogenic pathways in liver and kidney.  Nasser S, Solé T, Vega N, Thomas T, Balcerczyk A, Strigini M, Pirola L. Mol Metab. 2022 Aug 20:101578. doi: 10.1016/j.molmet.2022.101578. Online ahead of print. PMID: 35995402
Plant-Based and Ketogenic Diets As Diverging Paths to Address Cancer: A Review.  Shah UA, Iyengar NM. JAMA Oncol. 2022 Aug 1;8(8):1201-1208. doi: 10.1001/jamaoncol.2022.1769. PMID: 35797039 Review.

22nd August 2022

Title (click on the titles below to access to the paper) Author Trials Publisher
Efficacy and Safety of the Ketogenic Diet for Mitochondrial Disease With Epilepsy: A Prospective, Open-labeled, Controlled Study.  Huang L, Li H, Zhong J, Yang L, Chen G, Wang D, Zheng G, Han H, Han X, Long Y, Wang X, Liang J, Yu M, Shen X, Fan M, Fang F, Liao J, Sun D. Front Neurol. 2022 Aug 1;13:880944. doi: 10.3389/fneur.2022.880944. eCollection 2022. PMID: 35979062 Free PMC article.
The CORE-KDT study: a mixed methods protocol to establish core outcomes for refractory childhood epilepsy treated with ketogenic diet therapy.  Carroll JH, Cross JH, Hickson M, Williams E, Aldridge V, Collinson A. Trials. 2022 Aug 17;23(1):675. doi: 10.1186/s13063-022-06629-7. PMID: 35978413 Free PMC article.
The impact of dieting culture is different between sexes in endurance athletes: a cross-sectional analysis.  Graybeal AJ, Kreutzer A, Willis JL, Braun-Trocchio R, Moss K, Shah M. BMC Sports Sci Med Rehabil. 2022 Aug 17;14(1):157. doi: 10.1186/s13102-022-00549-4. PMID: 35978366 Free PMC article.
The ketogenic diet prevents steatosis and insulin resistance by reducing lipogenesis, diacylglycerol accummulation, and PKC activity in male rat liver.  Jani S, Da Eira D, Stefanovic M, Ceddia RB. J Physiol. 2022 Aug 16. doi: 10.1113/JP283552. Online ahead of print. PMID: 35974660
Expanding Indications for a Ketogenic Diet as an Adjuvant Therapy in Adult Refractory Status Epilepticus: an Exploratory Study Using Moderation Analysis.  Koh S, Kim TJ, Shin HB, Kim HK, Park B, Moon SY, Kim BG, Huh K, Choi JY. Neurotherapeutics. 2022 Aug 16. doi: 10.1007/s13311-022-01282-z. Online ahead of print. PMID: 35974294
Antiseizure medication reduction and withdrawal in children with drug-resistant epilepsy after starting the ketogenic diet.  Gogou M, Pujar S, Nemani T, Chiang C, Simpson Z, Hardy I, Schoeler N, Cross JH, Eltze C. Dev Med Child Neurol. 2022 Aug 15. doi: 10.1111/dmcn.15377. Online ahead of print. PMID: 35971594
Time-Restricted Ketogenic Diet in Huntington’s Disease: A Case Study.  Phillips MCL, McManus EJ, Brinkhuis M, Romero-Ferrando B. Front Behav Neurosci. 2022 Jul 29;16:931636. doi: 10.3389/fnbeh.2022.931636. eCollection 2022. PMID: 35967897 Free PMC article.
 A Comparison of the Impact of Restrictive Diets on the Gastrointestinal Tract of Mice.  Gregor A, Huber L, Auernigg-Haselmaier S, Sternberg F, Billerhart M, Dunkel A, Somoza V, Ogris M, Kofler B, Longo VD, König J, Duszka K. Nutrients. 2022 Jul 29;14(15):3120. doi: 10.3390/nu14153120. PMID: 35956298 Free PMC article
Keto is Trending: Implications for Body Weight and Lipid Management.  Kirkpatrick CF, Willard KE, Maki KC. Curr Cardiol Rep. 2022 Sep;24(9):1093-1100. doi: 10.1007/s11886-022-01731-3. Epub 2022 Jul 6. PMID: 35794438 Review

8th August 2022

Title (click on the titles below to access to the paper) Author Trials Publisher
Answer to the critical remarks to the article by Khodabakhshi and colleagues reporting results from a randomized study on ketogenic diet.  Khodabakhshi A, Seyfried TN, Kalamian M, Davoodi SH. Clin Nutr. 2022 Jul 5:S0261-5614(22)00219-9. doi: 10.1016/j.clnu.2022.06.025. Online ahead of print. PMID: 35934580 No abstract available.
Adaptation to short-term extreme fat consumption alters intestinal lipid handling in male and female mice.  Morrow NM, Locatelli CAA, Trzaskalski NA, Klein CT, Hanson AA, Alhadi H, Tripathi I, Clément AC, Imran S, Lorenzen-Schmidt I, Mulvihill EE. Biochim Biophys Acta Mol Cell Biol Lipids. 2022 Aug 1:159208. doi: 10.1016/j.bbalip.2022.159208. Online ahead of print. PMID: 35926775
Ketogenic diet for focal epilepsy with SPTAN1 encephalopathy.  Kishimoto K, Nabatame S, Kagitani-Shimono K, Kato M, Tohyama J, Nakashima M, Matsumoto N, Ozono K. Epileptic Disord. 2022 Aug 1;24(4):726-728. doi: 10.1684/epd.2022.1441. PMID: 35925050 English. No abstract available.
Does exercise during a ketogenic diet effectively alter appetite sensation, appetite-regulating hormones, and body composition?  Valinejad A, Khodaei K. Exp Biol Med (Maywood). 2022 Aug 3:15353702221113862. doi: 10.1177/15353702221113862. Online ahead of print. PMID: 35920294
Ketogenic diet: new avenues to overcome colorectal cancer.  Xiang Y, Wang M, Miao H. Signal Transduct Target Ther. 2022 Aug 2;7(1):262. doi: 10.1038/s41392-022-01113-9. PMID: 35918319 Free PMC article. No abstract available.
Child Neurology: Initial Presentation of PCDH19-Related Epilepsy With New-Onset Refractory Status Epilepticus and Treatment With Anakinra.  Varughese RT, Karkare S, Poduri A, Kothare SV. Neurology. 2022 Aug 2;99(5):208-211. doi: 10.1212/WNL.0000000000200855. Epub 2022 Jun 3. PMID: 35914944
Supplementation of Regular Diet With Medium-Chain Triglycerides for Procognitive Effects: A Narrative Review.  Shcherbakova K, Schwarz A, Apryatin S, Karpenko M, Trofimov A. Front Nutr. 2022 Jul 15;9:934497. doi: 10.3389/fnut.2022.934497. eCollection 2022. PMID: 35911092 Free PMC article. Review.
Cognitive profile of male mice exposed to a Ketogenic Diet.  Ródenas-González F, Blanco-Gandía MC, Miñarro J, Rodríguez-Arias M. Physiol Behav. 2022 Oct 1;254:113883. doi: 10.1016/j.physbeh.2022.113883. Epub 2022 Jun 15. PMID: 35716801

1st August 2022

Title (click on the titles below to access to the paper) Author Trials Publisher
Effectiveness of a telehealth physiotherapist-delivered intensive dietary weight loss program combined with exercise in people with knee osteoarthritis and overweight or obesity: study protocol for the POWER randomized controlled trial.  Bennell KL, Jones SE, Hinman RS, McManus F, Lamb KE, Quicke JG, Sumithran P, Prendergast J, George ES, Holden MA, Foster NE, Allison K. BMC Musculoskelet Disord. 2022 Jul 30;23(1):733. doi: 10.1186/s12891-022-05685-z. PMID: 35907828
Consumption of oils and anthocyanins may positively modulate PPAR-γ expression in chronic noncommunicable diseases: A systematic review.  Brum ISDC, Mafra D, Moreira LSG, Teixeira KTR, Stockler-Pinto MB, Cardozo LFMF, Borges NA. Nutr Res. 2022 Jun 19;105:66-76. doi: 10.1016/j.nutres.2022.06.004. Online ahead of print. PMID: 35905655 Review.
Impaired ketogenesis ties metabolism to T cell dysfunction in COVID-19.  Karagiannis F, Peukert K, Surace L, Michla M, Nikolka F, Fox M, Weiss P, Feuerborn C, Maier P, Schulz S, Al B, Seeliger B, Welte T, David S, Grondman I, de Nooijer AH, Pickkers P, Kleiner JL, Berger MM, Brenner T, Putensen C; Bonn COVIMMUNE Consortium, Kato H, Garbi N, Netea MG, Hiller K, Placek K, Bode C, Wilhelm C. Nature. 2022 Jul 28. doi: 10.1038/s41586-022-05128-8. Online ahead of print. PMID: 35901960
Evaluation of ketogenic diet therapy in children diagnosed with drug-resistant epilepsy: a single-center experience.  Yıldırım GK, Yağcı M, Uygur AÇ, Özen H, Yarar C, Çarman KB. Turk J Pediatr. 2022;64(3):435-445. doi: 10.24953/turkjped.2020.3091. PMID: 35899556
Tackling Atherosclerosis via Selected Nutrition.  Vesnina A, Prosekov A, Atuchin V, Minina V, Ponasenko A. Int J Mol Sci. 2022 Jul 26;23(15):8233. doi: 10.3390/ijms23158233. PMID: 35897799 Review.
From Young to Older, the 4 Phases Method Is Efficient in Promoting Quick Weight, BMI, and Waist Circumference Reductions.  Ramuth E, Ramuth S, Pavão TRR, Biacchi KB, Bachi ALL. Healthcare (Basel). 2022 Jul 27;10(8):1398. doi: 10.3390/healthcare10081398. PMID: 35893221 Free PMC article.
Plasma Metabonomics in Insulin-Resistant Hypogonadic Patients Induced by Testosterone Treatment.  Zolla L, Grande G, Milardi D. Int J Mol Sci. 2022 Jul 14;23(14):7754. doi: 10.3390/ijms23147754. PMID: 35887101 Free PMC article.
Glutamate-Induced Deregulation of Krebs Cycle in Mitochondrial Encephalopathy Lactic Acidosis Syndrome Stroke-Like Episodes (MELAS) Syndrome Is Alleviated by Ketone Body Exposure.  Belal S, Goudenège D, Bocca C, Dumont F, Chao De La Barca JM, Desquiret-Dumas V, Gueguen N, Geffroy G, Benyahia R, Kane S, Khiati S, Bris C, Aranyi T, Stockholm D, Inisan A, Renaud A, Barth M, Simard G, Reynier P, Letournel F, Lenaers G, Bonneau D, Chevrollier A, Procaccio V. Biomedicines. 2022 Jul 11;10(7):1665. doi: 10.3390/biomedicines10071665. PMID: 35884972 Free PMC article.
A user preference analysis of commercial breath ketone sensors to inform the development of portable breath ketone sensors for diabetes management in young people.  Brew-Sam N, Desborough J, Parkinson A, Murugappan K, Daskalaki E, Brown E, Ebbeck H, Pedley L, Hannon K, Brown K, Pedley E, Ebbeck G, Tricoli A, Suominen H, Nolan CJ, Phillips C. PLoS One. 2022 Jul 25;17(7):e0269925. doi: 10.1371/journal.pone.0269925. eCollection 2022. PMID: 35877679 Free PMC article.
Citrate Synthase Insufficiency Leads to Specific Metabolic Adaptations in the Heart and Skeletal Muscles Upon Low-Carbohydrate Diet Feeding in Mice.  Sumi K, Hatanaka Y, Takahashi R, Wada N, Ono C, Sakamoto Y, Sone H, Iida K. Front Nutr. 2022 Jul 7;9:925908. doi: 10.3389/fnut.2022.925908. eCollection 2022. PMID: 35873436 Free PMC article.
The Ketogenic Diet for Refractory Mental Illness: A Retrospective Analysis of 31 Inpatients.  Danan A, Westman EC, Saslow LR, Ede G. Front Psychiatry. 2022 Jul 6;13:951376. doi: 10.3389/fpsyt.2022.951376. eCollection 2022. PMID: 35873236 Free PMC article.
Helpful or harmful? The impact of the ketogenic diet on eating disorder outcomes in type 1 diabetes mellitus.  Schneider S, Biggerstaff DL, Barber TM. Expert Rev Endocrinol Metab. 2022 Jul;17(4):319-331. doi: 10.1080/17446651.2022.2089112. Epub 2022 Jun 24. PMID: 35748612 Review.
Dietary regulation in health and disease.  Wu Q, Gao ZJ, Yu X, Wang P. Signal Transduct Target Ther. 2022 Jul 23;7(1):252. doi: 10.1038/s41392-022-01104-w. PMID: 35871218 Free PMC article. Review.
Effects of a ketogenic diet in women with PCOS with different uric acid concentrations: a prospective cohort study.  Yang M, Bai W, Jiang B, Wang Z, Wang X, Sun Y, Liu F, Cui G, Song X, Li J, Wu F. Reprod Biomed Online. 2022 Aug;45(2):391-400. doi: 10.1016/j.rbmo.2022.03.023. Epub 2022 Apr 2. PMID: 35732547

25th July 2022

Title (click on the titles below to access to the paper) Author Trials Publisher
Dietary regulation in health and disease.  Wu Q, Gao ZJ, Yu X, Wang P. Signal Transduct Target Ther. 2022 Jul 23;7(1):252. doi: 10.1038/s41392-022-01104-w. PMID: 35871218 Review.
 Fad Diets: Facts and Fiction.  Tahreem A, Rakha A, Rabail R, Nazir A, Socol CT, Maerescu CM, Aadil RM. Front Nutr. 2022 Jul 5;9:960922. doi: 10.3389/fnut.2022.960922. eCollection 2022. PMID: 35866077 Free PMC article. Review.
Emerging Role of Hepatic Ketogenesis in Fatty Liver Disease.  Mooli RGR, Ramakrishnan SK. Front Physiol. 2022 Jul 4;13:946474. doi: 10.3389/fphys.2022.946474. eCollection 2022. PMID: 35860662 Free PMC article. Review.
β-hydroxybutyrate reduces blastocyst viability via trophectoderm-mediated metabolic aberrations in mice.  Whatley EG, Truong TT, Wilhelm D, Harvey AJ, Gardner DK. Hum Reprod. 2022 Jul 20:deac153. doi: 10.1093/humrep/deac153. Online ahead of print. PMID: 35856159
Effects of Ketogenic Diet on Neuroinflammation in Neurodegenerative Diseases.  Jiang Z, Yin X, Wang M, Chen T, Wang Y, Gao Z, Wang Z. Aging Dis. 2022 Jul 11;13(4):1146-1165. doi: 10.14336/AD.2021.1217. eCollection 2022 Jul 11. PMID: 35855338 Free PMC article.
Ketogenic diets slow melanoma growth in vivo regardless of tumor genetics and metabolic plasticity.  Weber DD, Aminzadeh-Gohari S, Thapa M, Redtenbacher AS, Catalano L, Capelôa T, Vazeille T, Emberger M, Felder TK, Feichtinger RG, Koelblinger P, Dallmann G, Sonveaux P, Lang R, Kofler B. Cancer Metab. 2022 Jul 18;10(1):12. doi: 10.1186/s40170-022-00288-7. PMID: 35851093 Free PMC article.

18th July 2022

Title (click on the titles below to access to the paper) Author Trials Publisher
Efficacy of the ketogenic diet in Chinese adults versus children with drug-resistant epilepsy: A pilot study. He F, Qiu J, Li H, Guo H, Wang S, Ding Y, Xu S, Wang Z, Feng J, Zhang P, Ding M, Wang S. Epilepsy Behav. 2022 Jul 12;134:108820. doi: 10.1016/j.yebeh.2022.108820. Online ahead of print. PMID: 35839644
Obesity-Related Chronic Kidney Disease: Principal Mechanisms and New Approaches in Nutritional Management.  Stasi A, Cosola C, Caggiano G, Cimmarusti MT, Palieri R, Acquaviva PM, Rana G, Gesualdo L. Front Nutr. 2022 Jun 24;9:925619. doi: 10.3389/fnut.2022.925619. eCollection 2022. PMID: 35811945 Free PMC article. Review.
Koolen-de Vries syndrome associated with continuous spike-wave in sleep.  Khan AQ, Coorg RK, Gill D, Marini C, Myers KA. Epileptic Disord. 2022 Oct 1;24(5):1-6. doi: 10.1684/epd.2022.1452. PMID: 35811432 English.
A randomized, double-blind trial of triheptanoin for drug-resistant epilepsy in glucose transporter 1 deficiency syndrome.  Striano P, Auvin S, Collins A, Horvath R, Scheffer IE, Tzadok M, Miller I, Kay Koenig M, Lacy A, Davis R, Garcia-Cazorla A, Saneto RP, Brandabur M, Blair S, Koutsoukos T, De Vivo D. Epilepsia. 2022 Jul;63(7):1748-1760. doi: 10.1111/epi.17263. Epub 2022 May 21. PMID: 35441706 Clinical Trial.
Extensive Biventricular Cardiac Sarcoidosis Detected on FDG PET/CT Using a 72-Hour Ketogenic Diet Preparation Protocol.  Lu Y. Clin Nucl Med. 2022 Aug 1;47(8):728-729. doi: 10.1097/RLU.0000000000004119. Epub 2022 Mar 8. PMID: 35261354

11th July 2022

Title (click on the titles below to access to the paper) Author Trials Publisher
A technology assisted precision ketogenic diet intervention for cardio-renal-metabolic health in overweight or obese adults: Protocol for a randomized controlled trial.  Du Y, Wang J, Li S, Dennis B, Meireles C, Siddiqui N, Patel D, Gelfond J, Li C, Faruqui SH, Alaeddini A, Drel V, Tumova J, Ye H, Montellano R, Pena GA, Sharma K. Contemp Clin Trials. 2022 Jul 6:106845. doi: 10.1016/j.cct.2022.106845. Online ahead of print. PMID: 35809772
Metabolic Fate Is Defined by Amino Acid Nature in Gilthead Seabream Fed Different Diet Formulations.  Teodósio R, Aragão C, Conceição LEC, Dias J, Engrola S. Animals (Basel). 2022 Jul 2;12(13):1713. doi: 10.3390/ani12131713. PMID: 35804612 Free PMC article.
A medium-chain triglyceride containing ketogenic diet exacerbates cardiomyopathy in a CRISPR/Cas9 gene-edited rat model with Duchenne muscular dystrophy.  Fujikura Y, Kimura K, Yamanouchi K, Sugihara H, Hatakeyama M, Zhuang H, Abe T, Daimon M, Morita H, Komuro I, Oishi K. Sci Rep. 2022 Jul 8;12(1):11580. doi: 10.1038/s41598-022-15934-9. PMID: 35803994 Free PMC article.
A Comparative Study Evaluating the Effectiveness Between Ketogenic and Low-Carbohydrate Diets on Glycemic and Weight Control in Patients With Type 2 Diabetes Mellitus: A Systematic Review and Meta-Analysis.  Zaki HA, Iftikhar H, Bashir K, Gad H, Samir Fahmy A, Elmoheen A. Cureus. 2022 May 31;14(5):e25528. doi: 10.7759/cureus.25528. eCollection 2022 May. PMID: 35800806 Free PMC article. Review.
Plant-Based and Ketogenic Diets As Diverging Paths to Address Cancer: A Review.  Shah UA, Iyengar NM. JAMA Oncol. 2022 Jul 7. doi: 10.1001/jamaoncol.2022.1769. Online ahead of print. PMID: 35797039
Epilepsy and cognitive impairment in childhood and adolescence: A Mini review.  Felicia F, Pastorino GMG, Viggiano A, Dell’Isola GB, Dini G, Verrotti A, Coppola G. Curr Neuropharmacol. 2022 Jul 6. doi: 10.2174/1570159X20666220706102708. Online ahead of print. PMID: 35794776
Epilepsy and Autism Spectrum Disorder (ASD): The underlying Mechanisms and Therapy Targets related with Adenosine.  Guo M, Xie P, Liu S, Luan G, Li T. Curr Neuropharmacol. 2022 Jul 6. doi: 10.2174/1570159X20666220706100136. Online ahead of print. PMID: 35794774
Keto is Trending: Implications for Body Weight and Lipid Management.  Kirkpatrick CF, Willard KE, Maki KC. Curr Cardiol Rep. 2022 Jul 6. doi: 10.1007/s11886-022-01731-3. Online ahead of print. PMID: 35794438 Review.
The place of a ketogenic diet in the treatment of resistant epilepsy: a comprehensive review.  Cicek E, Sanlier N. Nutr Neurosci. 2022 Jul 5:1-14. doi: 10.1080/1028415X.2022.2095819. Online ahead of print. PMID: 35791085
Favorable response to classic ketogenic diet in a child with anti-GAD 65 antibody mediated super refractory status epilepticus.  Sivathanu D, Kewalramani D, Kumar Manokaran R. Epilepsy Behav Rep. 2022 Jun 7;19:100557. doi: 10.1016/j.ebr.2022.100557. eCollection 2022. PMID: 35789965 Free PMC article.
[Treatment of status epilepticus in children and adults]. Sidaros A, Boxill MF, Christensen J, Hoei-Hansen CE, Beier CP. Ugeskr Laeger. 2022 Jun 27;184(26):V02220079. PMID: 35786229 Review. Danish.
[Basic and advanced treatment of children and adults with epilepsy].  Hoei-Hansen CE, Tinggaard J, Kløvgaard M, Sabers A. Ugeskr Laeger. 2022 Jun 27;184(26):V01220072. PMID: 35786227 Review. Danish.
 Potential for Ketotherapies as Amyloid-Regulating Treatment in Individuals at Risk for Alzheimer’s Disease.  Taylor MK, Sullivan DK, Keller JE, Burns JM, Swerdlow RH. Front Neurosci. 2022 Jun 16;16:899612. doi: 10.3389/fnins.2022.899612. eCollection 2022. PMID: 35784855 Free PMC article. Review.
Beta-Hydroxybutyrate: A Dual Function Molecular and Immunological Barrier Function Regulator.  Qi J, Gan L, Fang J, Zhang J, Yu X, Guo H, Cai D, Cui H, Gou L, Deng J, Wang Z, Zuo Z. Front Immunol. 2022 Jun 16;13:805881. doi: 10.3389/fimmu.2022.805881. eCollection 2022. PMID: 35784364 Free PMC article. Review.
Ketone Bodies Improve Human CD8+ Cytotoxic T-Cell Immune Response During COVID-19 Infection.  Hirschberger S, Gellert L, Effinger D, Muenchhoff M, Herrmann M, Briegel JM, Zwißler B, Kreth S. Front Med (Lausanne). 2022 Jun 16;9:923502. doi: 10.3389/fmed.2022.923502. eCollection 2022. PMID: 35783654 Free PMC article.

4th July 2022

Title (click on the titles below to access to the paper) Author Trials Publisher
The gut microbiome as possible mediator of the beneficial effects of very low calorie ketogenic diet on type 2 diabetes and obesity: a narrative review.  Defeudis G, Rossini M, Khazrai YM, Pipicelli AMV, Brucoli G, Veneziano M, Strollo F; AMD-SID-SIEDP-Lifestyle Study Group Lazio, Bellia A, Bitterman O, Lauro D, Mora D, Santarelli E. Eat Weight Disord. 2022 Jul 1. doi: 10.1007/s40519-022-01434-2. Online ahead of print. PMID: 35773554 Review.
A systematic review of the efficacy of perampanel as treatment for myoclonic seizures and symptomatic myoclonus.  Mir A, Alghamdi A, Alotaibi W, Samreen D, Alotaibi M, Albaradie R, Bashir S. Epileptic Disord. 2022 Aug 1;24(4):1-14. doi: 10.1684/epd.2022.1439. PMID: 35770766 English.
Magnetic resonance spectroscopy as a promising modality for assessing ketogenic diet impact on the level of cerebral metabolites in the treatment of certain neurological disorders.  Machowiec PA, Maksymowicz M, Piecewicz-Szczęsna H. Ann Agric Environ Med. 2022 Jun 24;29(2):201-206. doi: 10.26444/aaem/145069. Epub 2021 Dec 28. PMID: 35767751 Review.
Genome-wide decrease in DNA methylation in adults with epilepsy treated with modified ketogenic diet: A prospective study.  Pedersen S, Kverneland M, Nakken KO, Rudi K, Iversen PO, Gervin K, Selmer KK. Epilepsia. 2022 Jun 28. doi: 10.1111/epi.17351. Online ahead of print. PMID: 35762681
Correction to: Ketogenic diet and cognition in neurological diseases: a systematic review.  [No authors listed] Nutr Rev. 2022 Jun 28:nuac048. doi: 10.1093/nutrit/nuac048. Online ahead of print. PMID: 35762485 No abstract available.
Effects of the ketogenic diet on performance and body composition in athletes and trained adults: a systematic review and Bayesian multivariate multilevel meta-analysis and meta-regression.  Koerich ACC, Borszcz FK, Thives Mello A, de Lucas RD, Hansen F. Crit Rev Food Sci Nutr. 2022 Jun 27:1-26. doi: 10.1080/10408398.2022.2090894. Online ahead of print. PMID: 35757868
Immunomodulatory effect of a very-low-calorie ketogenic diet compared with bariatric surgery and a low-calorie diet in patients with excessive body weight.  Lorenzo PM, Sajoux I, Izquierdo AG, Gomez-Arbelaez D, Zulet MA, Abete I, Castro AI, Baltar J, Portillo MP, Tinahones FJ, Martinez JA, Casanueva FF, Crujeiras AB. Clin Nutr. 2022 Jul;41(7):1566-1577. doi: 10.1016/j.clnu.2022.05.007. Epub 2022 May 18. PMID: 35667273
Can the Ketogenic diet lead to Wernicke’s encephalopathy?  Javaid S, Lindenberg A, Srinivasan R. J Pediatr Rehabil Med. 2022;15(2):335-340. doi: 10.3233/PRM-200731. PMID: 35147570
Vagus nerve stimulation for super-refractory status epilepticus in febrile infection-related epilepsy syndrome: a pediatric case report and literature review.  Luo T, Wang Y, Lu G, Zhou Y, Wang Y. Childs Nerv Syst. 2022 Jul;38(7):1401-1404. doi: 10.1007/s00381-021-05410-6. Epub 2021 Nov 11. PMID: 34762158 Review.

27th June 2022

Title (click on the titles below to access to the paper) Author Trials Publisher
Fasting and the short-term consumption of a ketogenic diet are sufficient interventions to protect against OLZ-induced hyperglycemia in mice.  Budd JM, MacIntyre B. J Physiol. 2022 Jun 25. doi: 10.1113/JP283308. Online ahead of print. PMID: 35751570 No abstract available.
Helpful or harmful? The impact of the ketogenic diet on eating disorder outcomes in type 1 diabetes mellitus.  Schneider S, Biggerstaff D, Barber TM. Expert Rev Endocrinol Metab. 2022 Jun 24:1-13. doi: 10.1080/17446651.2022.2089112. Online ahead of print. PMID: 35748612
How Diet and Physical Activity Modulate Gut Microbiota: Evidence, and Perspectives.  Campaniello D, Corbo MR, Sinigaglia M, Speranza B, Racioppo A, Altieri C, Bevilacqua A. Nutrients. 2022 Jun 14;14(12):2456. doi: 10.3390/nu14122456. PMID: 35745186 Free PMC article. Review.
Very Low-Calorie Ketogenic Diet: A Potential Application in the Treatment of Hypercortisolism Comorbidities.  Guarnotta V, Emanuele F, Amodei R, Giordano C. Nutrients. 2022 Jun 9;14(12):2388. doi: 10.3390/nu14122388. PMID: 35745118 Free PMC article. Review.
Ketogenic and Modified Mediterranean Diet as a Tool to Counteract Neuroinflammation in Multiple Sclerosis: Nutritional Suggestions.  Di Majo D, Cacciabaudo F, Accardi G, Gambino G, Giglia G, Ferraro G, Candore G, Sardo P. Nutrients. 2022 Jun 8;14(12):2384. doi: 10.3390/nu14122384. PMID: 35745113 Free PMC article. Review.
 One Molecule for Mental Nourishment and More: Glucose Transporter Type 1-Biology and Deficiency Syndrome.  Vulturar R, Chiș A, Pintilie S, Farcaș IM, Botezatu A, Login CC, Sitar-Taut AV, Orasan OH, Stan A, Lazea C, Al-Khzouz C, Mager M, Vințan MA, Manole S, Damian L. Biomedicines. 2022 May 26;10(6):1249. doi: 10.3390/biomedicines10061249. PMID: 35740271 Free PMC article. Review.
Effects of a ketogenic diet in women with PCOS with different uric acid concentrations: a prospective cohort study.  Yang M, Bai W, Jiang B, Wang Z, Wang X, Sun Y, Liu F, Cui G, Song X, Li J, Wu F. Reprod Biomed Online. 2022 Apr 2:S1472-6483(22)00219-X. doi: 10.1016/j.rbmo.2022.03.023. Online ahead of print. PMID: 35732547
Targeted gut microbiota manipulation attenuates seizures in a model of infantile spasms syndrome.  Mu C, Nikpoor N, Tompkins TA, Choudhary A, Wang M, Marks WN, Rho JM, Scantlebury MH, Shearer J. JCI Insight. 2022 Jun 22;7(12):e158521. doi: 10.1172/jci.insight.158521. PMID: 35730569
Cognitive, Sleep, and Autonomic Responses to Induction of a Ketogenic Diet in Military Personnel: A Pilot Study.  Shaw DM, Henderson L, van den Berg M. Aerosp Med Hum Perform. 2022 Jun 1;93(6):507-516. doi: 10.3357/AMHP.6015.2022. PMID: 35729758 Clinical Trial.
Ketogenic diet as a chemopreventative and therapeutic strategy for colon cancer.  Pinato DJ. Gastroenterology. 2022 Jun 18:S0016-5085(22)00664-3. doi: 10.1053/j.gastro.2022.06.046. Online ahead of print. PMID: 35728685 No abstract available.
Diet and Sudden Death: How to Reduce the Risk.  Manolis AS, Manolis TA, Manolis AA, Melita H. Curr Vasc Pharmacol. 2022 Jun 21. doi: 10.2174/1570161120666220621090343. Online ahead of print. PMID: 35726434
Changes in Adiposity and Cerebrospinal Fluid Biomarkers Following a Modified Mediterranean Ketogenic Diet in Older Adults at Risk for Alzheimer’s Disease.  Brinkley TE, Leng I, Register TC, Neth BJ, Zetterberg H, Blennow K, Craft S. Front Neurosci. 2022 Jun 2;16:906539. doi: 10.3389/fnins.2022.906539. eCollection 2022. PMID: 35720727 Free PMC article.
Systemic Ketone Replacement Does Not Improve Survival or Cancer Cachexia in Mice With Lung Cancer.  Langer HT, Ramsamooj S, Liang RJ, Grover R, Hwang SK, Goncalves MD. Front Oncol. 2022 Jun 3;12:903157. doi: 10.3389/fonc.2022.903157. eCollection 2022. PMID: 35719965 Free PMC article.
Review: Physiology and nutrition of late gestating and transition sows.  Theil PK, Farmer C, Feyera T. J Anim Sci. 2022 Jun 1;100(6):skac176. doi: 10.1093/jas/skac176. PMID: 35708593 Free PMC article.
Congress of Neurological Surgeons systematic review and evidence-based guidelines update on the role of cytotoxic chemotherapy and other cytotoxic therapies in the management of progressive glioblastoma in adults.  Germano IM, Ziu M, Wen P, Ormond DR, Olson JJ. J Neurooncol. 2022 Jun;158(2):225-253. doi: 10.1007/s11060-021-03900-w. Epub 2022 Feb 23. PMID: 35195819
The Ketogenic Diet and Alzheimer’s Disease.  Hersant H, Grossberg G J Nutr Health Aging. 2022;26(6):606-614. doi: 10.1007/s12603-022-1807-7. PMID: 35718870 Review.
Six-month effects of modified Atkins diet implementation on indices of cardiovascular disease risk in adults with epilepsy.  McDonald TJW, Diaz-Arias L, Vizthum D, Henry-Barron BJ, Schlechter H, Kossoff EH, Cervenka MC. Nutr Neurosci. 2022 Jul;25(7):1548-1557. doi: 10.1080/1028415X.2021.1875301. Epub 2021 Jan 23. PMID: 33487129
Increased Hippocampal Afterdischarge Threshold in Ketogenic Diet is Accompanied by Enhanced Kynurenine Pathway Activity.  Osuch B, Kołosowska K, Chmielewska N, Turzyńska D, Sobolewska A, Szyndler J, Maciejak P. Neurochem Res. 2022 Jul;47(7):2109-2122. doi: 10.1007/s11064-022-03605-0. Epub 2022 May 6. PMID: 35522366

13th June 2022

Title (click on the titles below to access to the paper) Author Trials Publisher
Ketogenic Diet Therapy for Drug-Resistant Epilepsy and Cognitive Impairment in Children With Tuberous Sclerosis Complex.  Fang Y, Li D, Wang M, Zhao X, Duan J, Gu Q, Li B, Zha J, Mei D, Bian G, Zhang M, Zhang H, Hu J, Yang L, Yu L, Li H, Liao J. Front Neurol. 2022 May 24;13:863826. doi: 10.3389/fneur.2022.863826. eCollection 2022. PMID: 35685742 Free PMC article.
Addition of Prebiotics to the Ketogenic Diet Improves Metabolic Profile but Does Not Affect Seizures in a Rodent Model of Infantile Spasms Syndrome.  Mu C, Pochakom A, Reimer RA, Choudhary A, Wang M, Rho JM, Scantlebury MH, Shearer J. Nutrients. 2022 May 26;14(11):2210. doi: 10.3390/nu14112210. PMID: 35684010 Free PMC article.
Nonketotic Hyperglycinemia: Insight into Current Therapies.  Nowak M, Chuchra P, Paprocka J. J Clin Med. 2022 May 27;11(11):3027. doi: 10.3390/jcm11113027. PMID: 35683414 Free PMC article. Review.
The Effectiveness of Intermittent Fasting, Time Restricted Feeding, Caloric Restriction, a Ketogenic Diet and the Mediterranean Diet as Part of the Treatment Plan to Improve Health and Chronic Musculoskeletal Pain: A Systematic Review.  Cuevas-Cervera M, Perez-Montilla JJ, Gonzalez-Muñoz A, Garcia-Rios MC, Navarro-Ledesma S. Int J Environ Res Public Health. 2022 May 30;19(11):6698. doi: 10.3390/ijerph19116698. PMID: 35682282 Free PMC article. Review.
Role of Ketogenic Diets in Multiple Sclerosis and Related Animal Models: An Updated Review.  Lin WS, Lin SJ, Liao PY, Suresh D, Hsu TR, Wang PY. Adv Nutr. 2022 Jun 9:nmac065. doi: 10.1093/advances/nmac065. Online ahead of print. PMID: 35679067
One size does not fit all; practical, personal tailoring of the diet to NAFLD patients.  Zelber-Sagi S, Sol Grinshpan L, Ivancovsky-Wajcman D, Goldenshluger A, Gepner Y. Liver Int. 2022 Jun 8. doi: 10.1111/liv.15335. Online ahead of print. PMID: 35675167 Review.
ß-Hydroxybutyrate Improves Mitochondrial Function After Transient Ischemia in the Mouse.  Lehto A, Koch K, Barnstorf-Brandes J, Viel C, Fuchs M, Klein J. Neurochem Res. 2022 Jun 8. doi: 10.1007/s11064-022-03637-6. Online ahead of print. PMID: 35674929
Possible Nonneurological Health Benefits of Ketogenic Diet: Review of Scientific Reports over the Past Decade.  Daria Gołąbek K, Regulska-Ilow B. J Obes. 2022 May 27;2022:7531518. doi: 10.1155/2022/7531518. eCollection 2022. PMID: 35669612 Free PMC article. Review.
Curative Effect of Prebiotics/Probiotics-Assisted Ketogenic Diet on Children with Refractory Epilepsy.  Su L, Li S, Sun B. Emerg Med Int. 2022 May 28;2022:1076053. doi: 10.1155/2022/1076053. eCollection 2022. PMID: 35669168 Free PMC article.
Ketone Body Rescued Seizure Behavior of LRP1 Deficiency in Drosophila by Modulating Glutamate Transport.  Zhang JM, Chen MJ, He JH, Li YP, Li ZC, Ye ZJ, Bao YH, Huang BJ, Zhang WJ, Kwan P, Mao YL, Qiao JD. J Mol Neurosci. 2022 Jun 7. doi: 10.1007/s12031-022-02026-6. Online ahead of print. PMID: 35668313
 Immunomodulatory effect of a very-low-calorie ketogenic diet compared with bariatric surgery and a low-calorie diet in patients with excessive body weight.  Lorenzo PM, Sajoux I, Izquierdo AG, Gomez-Arbelaez D, Zulet MA, Abete I, Castro AI, Baltar J, Portillo MP, Tinahones FJ, Martinez JA, Casanueva FF, Crujeiras AB. Clin Nutr. 2022 May 18;41(7):1566-1577. doi: 10.1016/j.clnu.2022.05.007. Online ahead of print. PMID: 35667273
Ketogenic dietary interventions in autosomal dominant polycystic kidney disease-a retrospective case series study: first insights into feasibility, safety and effects.  Strubl S, Oehm S, Torres JA, Grundmann F, Haratani J, Decker M, Vuong S, Kaur Bhandal A, Methot N, Haynie-Cion R, Meyer F, Siedek F, Korst U, Müller RU, Weimbs T. Clin Kidney J. 2021 Sep 13;15(6):1079-1092. doi: 10.1093/ckj/sfab162. eCollection 2022 Jun. PMID: 35664270 Free PMC article.
Can ketogenic dietary interventions slow disease progression in ADPKD: what we know and what we don’t.  Ong ACM, Torra R. Clin Kidney J. 2022 Apr 21;15(6):1034-1036. doi: 10.1093/ckj/sfac103. eCollection 2022 Jun. PMID: 35664267 Free PMC article.
Head circumference in glucose transporter 1 deficiency syndrome: Normal for individuals, abnormal as a group.  van Gemert LA, Leen WG, Draaisma JM, Roeleveld N, Willemsen MA. Eur J Paediatr Neurol. 2022 May;38:73-76. doi: 10.1016/j.ejpn.2022.04.005. Epub 2022 Apr 27. PMID: 35500464
Could the ketogenic diet induce a shift in thyroid function and support a metabolic advantage in healthy participants? A pilot randomized-controlled-crossover trial.  Iacovides S, Maloney SK, Bhana S, Angamia Z, Meiring RM. PLoS One. 2022 Jun 3;17(6):e0269440. doi: 10.1371/journal.pone.0269440. eCollection 2022. PMID: 35658056 Free PMC article. Clinical Trial.
Hmgcs2-mediated ketogenesis modulates high-fat diet-induced hepatosteatosis.  Asif S, Kim RY, Fatica T, Sim J, Zhao X, Oh Y, Denoncourt A, Cheung AC, Downey M, Mulvihill EE, Kim KH. Mol Metab. 2022 Jul;61:101494. doi: 10.1016/j.molmet.2022.101494. Epub 2022 Apr 12. PMID: 35421611 Free PMC article.
Assessing the landscape of STXBP1-related disorders in 534 individuals.  Xian J, Parthasarathy S, Ruggiero SM, Balagura G, Fitch E, Helbig K, Gan J, Ganesan S, Kaufman MC, Ellis CA, Lewis-Smith D, Galer P, Cunningham K, O’Brien M, Cosico M, Baker K, Darling A, Veiga de Goes F, El Achkar CM, Doering JH, Furia F, García-Cazorla Á, Gardella E, Geertjens L, Klein C, Kolesnik-Taylor A, Lammertse H, Lee J, Mackie A, Misra-Isrie M, Olson H, Sexton E, Sheidley B, Smith L, Sotero L, Stamberger H, Syrbe S, Thalwitzer KM, van Berkel A, van Haelst M, Yuskaitis C, Weckhuysen S, Prosser B, Son Rigby C, Demarest S, Pierce S, Zhang Y, Møller RS, Bruining H, Poduri A, Zara F, Verhage M, Striano P, Helbig I. Brain. 2022 Jun 3;145(5):1668-1683. doi: 10.1093/brain/awab327. PMID: 35190816 Free PMC article.

6th June 2022

Title (click on the titles below to access to the paper) Author Trials Publisher
Could the ketogenic diet induce a shift in thyroid function and support a metabolic advantage in healthy participants? A pilot randomized-controlled-crossover trial.  Iacovides S, Maloney SK, Bhana S, Angamia Z, Meiring RM. PLoS One. 2022 Jun 3;17(6):e0269440. doi: 10.1371/journal.pone.0269440. eCollection 2022. PMID: 35658056
Clinical and nutritional management of very-low-calorie ketogenic diet (VLCKD) in patients with psoriasis and obesity: a practical guide for the nutritionist.  Barrea L, Caprio M, Camajani E, Verde L, Elce A, Frias-Toral E, Ceriani F, Cucalón G, Garcia-Velasquez E, El Ghoch M, Colao A, Savastano S, Muscogiuri G. Crit Rev Food Sci Nutr. 2022 Jun 2:1-17. doi: 10.1080/10408398.2022.2083070. Online ahead of print. PMID: 35653127
Ketogenic diet for focal epilepsy with.  Kishimoto K, Nabatame S, Kagitani-Shimono K, Kato M, Tohyama J, Nakashima M, Matsumoto N, Ozono K. Epileptic Disord. 2022 Jun 1;24(4):1-3. doi: 10.1684/epd.2022.1441. PMID: 35653110 English. No abstract available.
Ketogenic dietary therapies for epilepsy: Experience in 160 patients over 18 years.  Ruiz Herrero J, Cañedo Villarroya E, García Peñas JJ, García Alcolea B, Gómez Fernández B, Puerta Macfarland LA, Pedrón-Giner C. An Pediatr (Engl Ed). 2022 May 29:S2341-2879(22)00123-5. doi: 10.1016/j.anpede.2022.05.001. Online ahead of print. PMID: 35650008
Effect of a Ketogenic Diet versus Mediterranean Diet on HbA1c in Individuals with Prediabetes and Type 2 Diabetes Mellitus: the Interventional Keto-Med Randomized Crossover Trial.  Gardner CD, Landry MJ, Perelman D, Petlura C, Durand LR, Aronica L, Crimarco A, Cunanan KM, Chang A, Dant CC, Robinson JL, Kim SH. Am J Clin Nutr. 2022 May 31:nqac154. doi: 10.1093/ajcn/nqac154. Online ahead of print. PMID: 35641199
Phase II study of ketogenic diets in relapsing multiple sclerosis: safety, tolerability and potential clinical benefits.  Brenton JN, Lehner-Gulotta D, Woolbright E, Banwell B, Bergqvist AGC, Chen S, Coleman R, Conaway M, Goldman MD. J Neurol Neurosurg Psychiatry. 2022 Jun;93(6):637-644. doi: 10.1136/jnnp-2022-329074. Epub 2022 Apr 13. PMID: 35418509 Clinical Trial.

30th May 2022

Title (click on the titles below to access to the paper) Author Trials Publisher
CDKL5 Deficiency Disorder-Related Epilepsy: A Review of Current and Emerging Treatment.  Hong W, Haviland I, Pestana-Knight E, Weisenberg JL, Demarest S, Marsh ED, Olson HE. CNS Drugs. 2022 May 28. doi: 10.1007/s40263-022-00921-5. Online ahead of print. PMID: 35633486 Review.
The Effect of Nutritional Ketosis on Aquaporin Expression in Apolipoprotein E-Deficient Mice: Potential Implications for Energy Homeostasis.  da Silva IV, Gullette S, Florindo C, Huang NK, Neuberger T, Ross AC, Soveral G, Castro R. Biomedicines. 2022 May 18;10(5):1159. doi: 10.3390/biomedicines10051159. PMID: 35625895 Free PMC article.
The effect of low-carbohydrate ketogenic diet in the management of obesity compared with low caloric, low-fat diet.  Al Aamri KS, Alrawahi AH, Al Busaidi N, Al Githi MS, Al Jabri K, Al Balushi F, Ronquillo-Talara R, Al Balushi S, Waly M. Clin Nutr ESPEN. 2022 Jun;49:522-528. doi: 10.1016/j.clnesp.2022.02.110. Epub 2022 Feb 24. PMID: 35623861
Dietary influences on symptomatic and non-symptomatic toxicities during cancer treatment: A narrative review.  Kim AJ, Hong DS, George GC. Cancer Treat Rev. 2022 May 13;108:102408. doi: 10.1016/j.ctrv.2022.102408. Online ahead of print. PMID: 35623220 Review.
Does Neuroinflammation Underlie the Cognitive Changes Observed With Dietary Interventions?  Robbins JP, Solito E. Front Neurosci. 2022 May 10;16:854050. doi: 10.3389/fnins.2022.854050. eCollection 2022. PMID: 35620671 Free PMC article. Review.
The effects of endogenously- and exogenously-induced hyperketonemia on exercise performance and adaptation.  Dearlove DJ, Soto Mota A, Hauton D, Pinnick K, Evans R, Miller J, Fischer R, Mccullagh JSO, Hodson L, Clarke K, Cox PJ. Physiol Rep. 2022 May;10(10):e15309. doi: 10.14814/phy2.15309. PMID: 35614576
Phase angle as an easy diagnostic tool for the nutritionist in the evaluation of inflammatory changes during the active stage of a very low-calorie ketogenic diet.  Barrea L, Muscogiuri G, Aprano S, Vetrani C, de Alteriis G, Varcamonti L, Verde L, Colao A, Savastano S. Int J Obes (Lond). 2022 May 25:1-7. doi: 10.1038/s41366-022-01152-w. Online ahead of print. PMID: 35614205 Free PMC article.
The effectiveness of the ketogenic diet in drug-resistant childhood epilepsy.  Yılmaz Ü, Edizer S, Akışin Z, Köse M, Güzin Y, Gürbüz G, Baysal BT, Sarıtaş S, Pekuz S, Kırkgöz HH, Yavuz M, Ünalp A. Turk J Pediatr. 2022;64(2):210-220. doi: 10.24953/turkjped.2021.4. PMID: 35611409
Clinical implementation of ketogenic diet in children with drug-resistant epilepsy: Advantages, disadvantages, and difficulties.  Tong X, Deng Y, Liu L, Tang X, Yu T, Gan J, Cai Q, Luo R, Xiao N. Seizure. 2022 Apr 29;99:75-81. doi: 10.1016/j.seizure.2022.04.015. Online ahead of print. PMID: 35609496
Quantitative Three-Dimensional Gait Evaluation in Patients With Glucose Transporter 1 Deficiency Syndrome.  Suzuki T, Ito Y, Ito T, Kidokoro H, Noritake K, Hattori A, Nabatame S, Natsume J. Pediatr Neurol. 2022 Apr 29;132:23-26. doi: 10.1016/j.pediatrneurol.2022.04.012. Online ahead of print. PMID: 35605310
Prurigo Pigmentosa Following a Keto Diet and Bariatric Surgery.  Alkhouri F, Alkhouri S, Potts GA. Cureus. 2022 Apr 20;14(4):e24307. doi: 10.7759/cureus.24307. eCollection 2022 Apr. PMID: 35602831 Free PMC article.
Ketogenic Diets and Hepatocellular Carcinoma.  Lan Y, Jin C, Kumar P, Yu X, Lenahan C, Sheng J. Front Oncol. 2022 May 4;12:879205. doi: 10.3389/fonc.2022.879205. eCollection 2022. PMID: 35600387 Free PMC article. Review.
Phenotypic spectrum and long-term outcome of children with genetic early-infantile-onset developmental and epileptic encephalopathy.  Hu C, Liu D, Luo T, Wang Y, Liu Z. Epileptic Disord. 2022 Apr 1;24(2):343-352. doi: 10.1684/epd.2021.1394. PMID: 34859793

23rd May 2022

Title (click on the titles below to access to the paper) Author Trials Publisher
Core outcome set development for childhood epilepsy treated with ketogenic diet therapy: Results of a scoping review and parent interviews.  Carroll JH, Martin-McGill KJ, Cross JH, Hickson M, Williams E, Aldridge V, Collinson A. Seizure. 2022 May 13;99:54-67. doi: 10.1016/j.seizure.2022.05.009. Online ahead of print. PMID: 35598573
Higher levels of Bifidobacteria and tumor necrosis factor in children with drug-resistant epilepsy are associated with anti-seizure response to the ketogenic diet.  Dahlin M, Singleton SS, David JA, Basuchoudhary A, Wickström R, Mazumder R, Prast-Nielsen S. EBioMedicine. 2022 May 18;80:104061. doi: 10.1016/j.ebiom.2022.104061. Online ahead of print. PMID: 35598439
Effects of Low-Carbohydrate Diet and Exercise Training on Gut Microbiota.  Sun S, Lei OK, Nie J, Shi Q, Xu Y, Kong Z. Front Nutr. 2022 May 3;9:884550. doi: 10.3389/fnut.2022.884550. eCollection 2022. PMID: 35592627 Free PMC article.
Long Term Survivals in Aggressive Primary Brain Malignancies Treated With an Adjuvant Ketogenic Diet.  Schwartz KA, Noel M, Nikolai M, Olson LK, Hord NG, Zakem M, Clark J, Elnabtity M, Figueroa B, Chang HT. Front Nutr. 2022 May 3;9:770796. doi: 10.3389/fnut.2022.770796. eCollection 2022. PMID: 35592625 Free PMC article.
Ketotherapy: Cutting carbs to treat cancer.  Radyk MD, Kerk SA, Lyssiotis CA. Med (N Y). 2022 Feb 11;3(2):87-89. doi: 10.1016/j.medj.2022.01.005. PMID: 35590211
Gut-based manipulations spur hippocampal mitochondrial bioenergetics in a model of pediatric epilepsy.  Mu C, Tompkins TA, Rho JM, Scantlebury MH, Shearer J. Biochim Biophys Acta Mol Basis Dis. 2022 May 16:166446. doi: 10.1016/j.bbadis.2022.166446. Online ahead of print. PMID: 35589071
Research Involvement in a Group of Registered Dietitian Nutritionists Specializing in Ketogenic Diet Therapies for Epilepsy.  Lowe J, Brown J, Klier K, Doll White J, Briceno Alliegro L, Sewak S, Mele-Hayes D. J Acad Nutr Diet. 2022 May 16:S2212-2672(22)00304-5. doi: 10.1016/j.jand.2022.05.013. Online ahead of print. PMID: 35589069
Ketogenic diet ameliorates inflammation by inhibiting the NLRP3 inflammasome in osteoarthritis.  Kong G, Wang J, Li R, Huang Z, Wang L. Arthritis Res Ther. 2022 May 18;24(1):113. doi: 10.1186/s13075-022-02802-0. PMID: 35585627 Free PMC article.
Fasting induces a highly resilient deep quiescent state in muscle stem cells via ketone body signaling.  Benjamin DI, Both P, Benjamin JS, Nutter CW, Tan JH, Kang J, Machado LA, Klein JDD, de Morree A, Kim S, Liu L, Dulay H, Feraboli L, Louie SM, Nomura DK, Rando TA. Cell Metab. 2022 May 12:S1550-4131(22)00182-6. doi: 10.1016/j.cmet.2022.04.012. Online ahead of print. PMID: 35584694
An Isoproteic Cocoa Butter-Based Ketogenic Diet Fails to Improve Glucose Homeostasis and Promote Weight Loss in Obese Mice.  Greenwell AA, Saed CT, Tabatabaei-Dakhili SA, Ho KL, Gopal K, Chan JSF, Kaczmar OO, Dyer SA, Eaton F, Lopaschuk GD, Al Batran R, Ussher JR. Am J Physiol Endocrinol Metab. 2022 May 16. doi: 10.1152/ajpendo.00435.2021. Online ahead of print. PMID: 35575232
Short Term Isocaloric Ketogenic Diet Modulates NLRP3 Inflammasome Via B-hydroxybutyrate and Fibroblast Growth Factor 21.  Kim ER, Kim SR, Cho W, Lee SG, Kim SH, Kim JH, Choi E, Kim JH, Yu JW, Lee BW, Kang ES, Cha BS, Lee MS, Cho JW, Jeon JY, Lee YH. Front Immunol. 2022 Apr 28;13:843520. doi: 10.3389/fimmu.2022.843520. eCollection 2022. PMID: 35572519 Free PMC article. Clinical Trial.
Intermittent methionine restriction reduces IGF-1 levels and produces similar healthspan benefits to continuous methionine restriction.  Plummer JD, Johnson JE. Aging Cell. 2022 May 15:e13629. doi: 10.1111/acel.13629. Online ahead of print. PMID: 35570387
 Influence of Aging, Macronutrient Composition and Time-Restricted Feeding on the Fischer344 x Brown Norway Rat Gut Microbiota.  Hernandez AR, Kemp KM, Burke SN, Buford TW, Carter CS. Nutrients. 2022 Apr 22;14(9):1758. doi: 10.3390/nu14091758. PMID: 35565725 Free PMC article.  
Modulation of Dyslipidemia Markers Apo B/Apo A and Triglycerides/HDL-Cholesterol Ratios by Low-Carbohydrate High-Fat Diet in a Rat Model of Metabolic Syndrome.  Alnami A, Bima A, Alamoudi A, Eldakhakhny B, Sakr H, Elsamanoudy A. Nutrients. 2022 May 1;14(9):1903. doi: 10.3390/nu14091903. PMID: 35565871 Free PMC article.
Lactation ketoacidosis induced by breastfeeding while on a ketogenic diet.  Osborne KC, Oliver JJ. Am J Emerg Med. 2022 Jun;56:392.e5-392.e6. doi: 10.1016/j.ajem.2022.02.054. Epub 2022 Feb 27. PMID: 35277297

16th May 2022

Title (click on the titles below to access to the paper) Author Trials Publisher
The Therapeutic Role of Ketogenic Diet in Neurological Disorders.  Pietrzak D, Kasperek K, Rękawek P, Piątkowska-Chmiel I. Nutrients. 2022 May 6;14(9):1952. doi: 10.3390/nu14091952. PMID: 35565918 Free PMC article. Review.
Modulation of Dyslipidemia Markers Apo B/Apo A and Triglycerides/HDL-Cholesterol Ratios by Low-Carbohydrate High-Fat Diet in a Rat Model of Metabolic Syndrome.  Alnami A, Bima A, Alamoudi A, Eldakhakhny B, Sakr H, Elsamanoudy A. Nutrients. 2022 May 1;14(9):1903. doi: 10.3390/nu14091903. PMID: 35565871 Free PMC article.
Ketogenic Diet and Weight Loss: Is There an Effect on Energy Expenditure?  Basolo A, Magno S, Santini F, Ceccarini G. Nutrients. 2022 Apr 26;14(9):1814. doi: 10.3390/nu14091814. PMID: 35565778 Free PMC article. Review.
Fish Oil Enriched n-3 Polyunsaturated Fatty Acids Improve Ketogenic Low-Carbohydrate/High-Fat Diet-Caused Dyslipidemia, Excessive Fat Accumulation, and Weight Control in Rats.  Liu SH, Chen YX, Tzeng HP, Chiang MT. Nutrients. 2022 Apr 25;14(9):1796. doi: 10.3390/nu14091796. PMID: 35565762 Free PMC article.
Influence of Aging, Macronutrient Composition and Time-Restricted Feeding on the Fischer344 x Brown Norway Rat Gut Microbiota.  Hernandez AR, Kemp KM, Burke SN, Buford TW, Carter CS. Nutrients. 2022 Apr 22;14(9):1758. doi: 10.3390/nu14091758. PMID: 35565725 Free PMC article.
Effects of Classic Ketogenic Diet in Children with Refractory Epilepsy: A Retrospective Cohort Study in Kingdom of Bahrain.  Perna S, Ferraris C, Guglielmetti M, Alalwan TA, Mahdi AM, Guido D, Tagliabue A. Nutrients. 2022 Apr 22;14(9):1744. doi: 10.3390/nu14091744. PMID: 35565714 Free PMC article.
Nutrition interventions in congenital disorders of glycosylation.  Boyer SW, Johnsen C, Morava E. Trends Mol Med. 2022 May 10:S1471-4914(22)00081-8. doi: 10.1016/j.molmed.2022.04.003. Online ahead of print. PMID: 35562242 Review.
Oral administration of a novel, synthetic ketogenic compound elevates blood β-hydroxybutyrate levels in mice in both food-restricted and ab-libitum conditions.  Soliven MA, Williams MS, Rogers CQ, D’Agostino DP. FASEB J. 2022 May;36 Suppl 1. doi: 10.1096/fasebj.2022.36.S1.R5778. PMID: 35557145
A Low-carbohydrate, Ketogenic Diet Enhances Hippocampal Mitochondrial Bioenergetics and Efficiency.  Saito ER, Warren CE, Campbell RJ, Miller G, du Randt JD, Cannon ME, Saito JY, Hanegan CM, Kemberling CM, Edwards JG, Bikman BT. FASEB J. 2022 May;36 Suppl 1. doi: 10.1096/fasebj.2022.36.S1.R5607. PMID: 35556976
Developing a Pipeline for Personalized Diagnoses of Glut1 Deficiency Syndrome.  Griffith L, Donohue K, Abul-Khoudoud M, Gentry M. FASEB J. 2022 May;36 Suppl 1. doi: 10.1096/fasebj.2022.36.S1.R5375. PMID: 35556721
Ketones Improve the Mitochondrial Coupling Efficiency of Brown Adipocytes.  Moazzami Z, Crawford P, Ruan HB. FASEB J. 2022 May;36 Suppl 1. doi: 10.1096/fasebj.2022.36.S1.R4195. PMID: 35556671
Eating a high fat or ketogenic diet increases sensitivity of rats to methamphetamine-induced locomotion.  Elsey M, Beltran NM, Serafine KM. FASEB J. 2022 May;36 Suppl 1. doi: 10.1096/fasebj.2022.36.S1.L7491. PMID: 35555750
Effects of a ketogenic diet on recognition memory and locomotor activity.  Warren CE, Saito E, Miller G, du Randt JD, Cannon ME, Bikman BT. FASEB J. 2022 May;36 Suppl 1. doi: 10.1096/fasebj.2022.36.S1.R5779. PMID: 35555698
Investigating the Link Between the Gut Microbiome and Epilepsy in Zebrafish.  Woodis KM, Uno JK. FASEB J. 2022 May;36 Suppl 1. doi: 10.1096/fasebj.2022.36.S1.R4480. PMID: 35553928
Male and Female Mice Respond Differently to Short-term Ketogenic Diet.  Sprankle KW, Knappenberger MA, Locke EJ, Knapsack K, Vinovrski MF, Kolwicz SC Jr. FASEB J. 2022 May;36 Suppl 1. doi: 10.1096/fasebj.2022.36.S1.R5815. PMID: 35553622
The Ketogenic Diet Impairs Mitochondrial Function in Hearts of Male and Female Mice.  Locke EJ, Vinovrski MF, Walborn L, Schreffler R, Knappenberger MA, Sprankle KW, Kolwicz SC Jr. FASEB J. 2022 May;36 Suppl 1. doi: 10.1096/fasebj.2022.36.S1.R5954. PMID: 35553554
Postprandial Responses of Energy Substrates in Dogs Fed High Fat- vs High Protein-Low Carbohydrate Ketogenic Foods Relative to a High Carbohydrate Food.  Jackson MI. FASEB J. 2022 May;36 Suppl 1. doi: 10.1096/fasebj.2022.36.S1.R5051. PMID: 35553448
Understanding the endocrine response to macronutrients in the context of a ketogenic diet.  Deru L, Warren C, Wright B, Coleman J, Duersch A, Chan H, Hales K, Bailey B, Bikman B. FASEB J. 2022 May;36 Suppl 1. doi: 10.1096/fasebj.2022.36.S1.R6073. PMID: 35552192
Colorectal Cancer Growth Is Reduced by the Ketone Body β-Hydroxybutyrate.  [No authors listed] Cancer Discov. 2022 May 13:OF1. doi: 10.1158/2159-8290.CD-RW2022-084. Online ahead of print. PMID: 35551354
Low-Carbohydrate Ketogenic Diet for Improvement of Glycemic Control: Mechanism of Action of Ketosis and Beneficial Effects.  Sakr HF, Sirasanagandla SR, Das S, Bima AI, Elsamanoudy AZ. Curr Diabetes Rev. 2022 May 11. doi: 10.2174/1573399818666220511121629. Online ahead of print. PMID: 35546779
Ameliorating effect of ketogenic diet on acute status epilepticus: Insights into biochemical and histological changes in rat hippocampus.  Shehata NI, Abdelsamad MA, Amin HAA, Sadik NAH, Shaheen AA. J Food Biochem. 2022 May 11:e14217. doi: 10.1111/jfbc.14217. Online ahead of print. PMID: 35543175
Type 2 Myocardial Infarction Related to Very Low Carbohydrate Ketogenic Diet.  Taha A, Ahmed S, Ahmed Mbbs R, Mohammed Md A. J Investig Med High Impact Case Rep. 2022 Jan-Dec;10:23247096221074879. doi: 10.1177/23247096221074879. PMID: 35272529 Free PMC article.
Ketogenic diet, epilepsy and cognition: what do we know so far? A systematic review.  Lima MC, Gabiatti MP, Moreira JD, Ribeiro LC, Lunardi MDS, Lin K, Venske DK. Nutr Rev. 2022 May 9:nuac021. doi: 10.1093/nutrit/nuac021. Online ahead of print. PMID: 35535020
The Glycemic Biomarkers in Children with Drug-Resistant Epilepsy on Various Types of Ketogenic Diet Therapies: A Cross-sectional study.  Teng LY, Lee VW, Murugesu S, Lee JX, Ibrahim NS, Ishak MF, Mohamed AR, Khoo TB. Epilepsia. 2022 May 8. doi: 10.1111/epi.17292. Online ahead of print. PMID: 35527506

9th May 2022

Title (click on the titles below to access to the paper) Author Trials Publisher
From the Ketogenic Diet to the Mediterranean Diet: The Potential Dietary Therapy in Patients with Obesity after CoVID-19 Infection (Post CoVID Syndrome).  Barrea L, Vetrani C, Caprio M, Cataldi M, Ghoch ME, Elce A, Camajani E, Verde L, Savastano S, Colao A, Muscogiuri G. Curr Obes Rep. 2022 May 6:1-22. doi: 10.1007/s13679-022-00475-z. Online ahead of print. PMID: 35524067 Free PMC article. Review.
Increased Hippocampal Afterdischarge Threshold in Ketogenic Diet is Accompanied by Enhanced Kynurenine Pathway Activity.  Osuch B, Kołosowska K, Chmielewska N, Turzyńska D, Sobolewska A, Szyndler J, Maciejak P. Neurochem Res. 2022 May 6. doi: 10.1007/s11064-022-03605-0. Online ahead of print. PMID: 35522366
Fasting or the short-term consumption of a ketogenic diet protects against antipsychotic-induced hyperglycemia in mice.  Shamshoum H, Medak KD, McKie GL, Hahn MK, Wright DC. J Physiol. 2022 May 4. doi: 10.1113/JP282922. Online ahead of print. PMID: 35507699
Effects of a Ketogenic Diet on Symptoms, Biomarkers, Depression, and Anxiety in Parkinson’s Disease: A Case Study.  Tidman M. Cureus. 2022 Mar 31;14(3):e23684. doi: 10.7759/cureus.23684. eCollection 2022 Mar. PMID: 35505754 Free PMC article.
KetoCycle mobile app for ketogenic diet: a retrospective study of weight loss and engagement.  Valinskas S, Aleknavicius K, Jonusas J. BMC Nutr. 2022 May 2;8(1):40. doi: 10.1186/s40795-022-00539-2. PMID: 35501935 Free PMC article.
A ketogenic diet prevents methylglyoxal-evoked nociception by scavenging methylglyoxal.  Enders JD, Thomas S, Swanson MT, Ryals JM, Wright DE. Pain. 2022 Apr 28. doi: 10.1097/j.pain.0000000000002667. Online ahead of print. PMID: 35500286
Ketogenic Diet Modulates Neuroinflammation via Metabolites from Lactobacillus reuteri After Repetitive Mild Traumatic Brain Injury in Adolescent Mice.  Dilimulati D, Zhang F, Shao S, Lv T, Lu Q, Cao M, Jin Y, Jia F, Zhang X. Cell Mol Neurobiol. 2022 Apr 30. doi: 10.1007/s10571-022-01226-3. Online ahead of print. PMID: 35499776
Impact of a ketogenic diet intervention during radiotherapy on body composition: V. Final results of the KETOCOMP study for head and neck cancer patients.  Klement RJ, Sweeney RA. Strahlenther Onkol. 2022 May 2:1-13. doi: 10.1007/s00066-022-01941-2. Online ahead of print. PMID: 35499696 Free PMC article.
Case Report: Hypercholesterolemia “Lean Mass Hyper-Responder” Phenotype Presents in the Context of a Low Saturated Fat Carbohydrate-Restricted Diet.  Norwitz NG, Soto-Mota A, Feldman D, Parpos S, Budoff M. Front Endocrinol (Lausanne). 2022 Apr 14;13:830325. doi: 10.3389/fendo.2022.830325. eCollection 2022. PMID: 35498420 Free PMC article.
A Possible Antidepressive Effect of Dietary Interventions: Emergent Findings and Research Challenges.  Ceolin G, Breda V, Koning E, Meyyappan AC, Gomes FA, Moreira JD, Gerchman F, Brietzke E. Curr Treat Options Psychiatry. 2022 Apr 23:1-12. doi: 10.1007/s40501-022-00259-1. Online ahead of print. PMID: 35496470 Free PMC article. Review.
Effects of ketogenic diet on cognitive functions of mice fed high-fat-high-cholesterol diet.  Lin DT, Kao NJ, Cross TL, Lee WJ, Lin SH. J Nutr Biochem. 2022 Jun;104:108974. doi: 10.1016/j.jnutbio.2022.108974. Epub 2022 Feb 20. PMID: 35196576
Critical remarks to the article by Khodabakhshi and colleagues reporting results from a randomized study on ketogenic diet.  Huebner J, Keinki C, Käsmann L; working group Prevention and Integrative Oncology of the German Cancer Society. Clin Nutr. 2022 May;41(5):1149. doi: 10.1016/j.clnu.2022.03.004. Epub 2022 Mar 25. PMID: 35393135 No abstract available.

2nd May 2022

Title (click on the titles below to access to the paper) Author Trials Publisher
The effect of the ketogenic diet on leptin, chemerin and resistin levels in children with epilepsy.  Chyra M, Swietochowska E, Gorska-Flak K, Dudzinska M, Oswiecimska J. Neuro Endocrinol Lett. 2021 Nov 30;42(7):489-499. Online ahead of print. PMID: 35490359
Correction to: Ketogenic diet impairs neurological development of neonatal rats and affects biochemical composition of maternal brains: evidence of functional recovery in pups.  Kosiek W, Rauk Z, Szulc P, Cichy A, Rugieł M, Chwiej J, Janeczko K, Setkowicz Z. Brain Struct Funct. 2022 Apr 29. doi: 10.1007/s00429-022-02500-2. Online ahead of print. PMID: 35486187 No abstract available.
Migraine and Diet: Updates in Understanding.  Moskatel LS, Zhang N. Curr Neurol Neurosci Rep. 2022 Apr 28. doi: 10.1007/s11910-022-01195-6. Online ahead of print. PMID: 35482279 Review.
A Ketogenic Diet is Effective in Improving Insulin Sensitivity in Individuals with Type 2 Diabetes.  Skow SL, Jha RK. Curr Diabetes Rev. 2022 Apr 25. doi: 10.2174/1573399818666220425093535. Online ahead of print. PMID: 35469570
The gut microbiome and the ketogenic diet: A pathway towards treatment optimization in infantile spasms.  McCafferty C. E BioMedicine. 2022 Apr;78:103924. doi: 10.1016/j.ebiom.2022.103924. Epub 2022 Mar 23. PMID: 35339095 Free PMC article. No abstract available.
Ketogenic diet ameliorates cognitive impairment and neuroinflammation in a mouse model of Alzheimer’s disease.  Xu Y, Jiang C, Wu J, Liu P, Deng X, Zhang Y, Peng B, Zhu Y. CNS Neurosci Ther. 2022 Apr;28(4):580-592. doi: 10.1111/cns.13779. Epub 2021 Dec 10. PMID: 34889516 Free PMC article.

25th April 2022

Title (click on the titles below to access to the paper) Author Trials Publisher
Insight into the cellular interactions and molecular mechanisms of ketogenic diet for comprehensive management of epilepsy.  Kumar A, Kumari S, Singh D. Curr Neuropharmacol. 2022 Apr 20. doi: 10.2174/1570159X20666220420130109. Online ahead of print. PMID: 35450526
Potentials of ketogenic diet against chronic kidney diseases: pharmacological insights and therapeutic prospects.  Kundu S, Hossain KS, Moni A, Zahan MS, Rahman MM, Uddin MJ. Mol Biol Rep. 2022 Apr 20. doi: 10.1007/s11033-022-07460-8. Online ahead of print. PMID: 35441940 Review.
A randomized, double-blind trial of triheptanoin for drug-resistant epilepsy in glucose transporter I deficiency syndrome (Glut1DS).  Striano P, Auvin S, Collins A, Horvath R, Scheffer IE, Tzadok M, Miller I, Koenig MK, Lacy A, Davis R, Garcia-Cazorla A, Saneto RP, Brandabur M, Blair S, Koutsoukos T, De Vivo D. Epilepsia. 2022 Apr 20. doi: 10.1111/epi.17263. Online ahead of print. PMID: 35441706
Low-carbohydrate and ketogenic diets: a scoping review of neurological and inflammatory outcomes in human studies and their relevance to chronic pain.  Field R, Field T, Pourkazemi F, Rooney K. Nutr Res Rev. 2022 Apr 19:1-71. doi: 10.1017/S0954422422000087. Online ahead of print. PMID: 35438071 Review.
Short-Term Ketogenic Diet Induces a Molecular Response That Is Distinct From Dietary Protein Restriction.  Kalafut KC, Mitchell SJ, MacArthur MR, Mitchell JR. Front Nutr. 2022 Mar 30;9:839341. doi: 10.3389/fnut.2022.839341. eCollection 2022. PMID: 35433789 Free PMC article.
Positive impact of a modified Atkins diet on cognition, seizure control, and abnormal movements in an adult with glucose transporter type 1 deficiency syndrome: case report.  Diaz-Arias LA, Henry-Barron BJ, Buchholz A, Cervenka MC. Neurol Sci. 2022 May;43(5):3449-3452. doi: 10.1007/s10072-022-05973-5. Epub 2022 Mar 3. PMID: 35243547 No abstract available.
Lowering apolipoprotein CIII protects against high-fat diet-induced metabolic derangements.  Valladolid-Acebes I, Åvall K, Recio-López P, Moruzzi N, Bryzgalova G, Björnholm M, Krook A, Alonso EF, Ericsson M, Landfors F, Nilsson SK, Berggren PO, Juntti-Berggren L. Sci Adv. 2021 Mar 12;7(11):eabc2931. doi: 10.1126/sciadv.abc2931. Print 2021 Mar. PMID: 33712458 Free PMC article.

18th April 2022

Title (click on the titles below to access to the paper) Author Trials Publisher
Ketogenic diet and chemotherapy combine to disrupt pancreatic cancer metabolism and growth.  Yang L, TeSlaa T, Ng S, Nofal M, Wang L, Lan T, Zeng X, Cowan A, McBride M, Lu W, Davidson S, Liang G, Oh TG, Downes M, Evans R, Von Hoff D, Guo JY, Han H, Rabinowitz JD. Med (N Y). 2022 Feb 11;3(2):119-136. doi: 10.1016/j.medj.2021.12.008. PMID: 35425930
Hmgcs2-mediated ketogenesis modulates high-fat diet-induced hepatosteatosis.  Asif S, Kim RY, Fatica T, Sim J, Zhao X, Oh Y, Denoncourt A, Cheung A, Downey M, Mulvihill EE, Kim KH. Mol Metab. 2022 Apr 11:101494. doi: 10.1016/j.molmet.2022.101494. Online ahead of print. PMID: 35421611
The Use of SGLT-2 Inhibitors Coupled With a Strict Low-Carbohydrate Diet: A Set-Up for Inducing Severe Diabetic Ketoacidosis.  Guirguis H, Beroukhim Afrahimi S, Pham C. Clin Med Insights Case Rep. 2022 Apr 8;15:11795476221090045. doi: 10.1177/11795476221090045. eCollection 2022. PMID: 35418794 Free PMC article.
Phase II study of ketogenic diets in relapsing multiple sclerosis: safety, tolerability and potential clinical benefits.  Brenton JN, Lehner-Gulotta D, Woolbright E, Banwell B, Bergqvist AGC, Chen S, Coleman R, Conaway M, Goldman MD. J Neurol Neurosurg Psychiatry. 2022 Apr 13:jnnp-2022-329074. doi: 10.1136/jnnp-2022-329074. Online ahead of print. PMID: 35418509
Telemedicine- versus outpatient-based initiation and management of ketogenic diet therapy in children with drug-resistant epilepsy during the COVID-19 pandemic.  Armeno M, Caballero E, Verini A, Reyes G, Galarza N, Cresta A, Caraballo RH. Seizure. 2022 Apr 4;98:37-43. doi: 10.1016/j.seizure.2022.03.023. Online ahead of print. PMID: 35417828
Impact of ketogenic diet and ketone diester supplementation on body weight, blood glucose, and ketones in Sprague Dawley rats fed over two weeks.  Modica LCM, Flores-Felix K, Casachahua LJD, Asquith P, Tschiffely A, Ciarlone S, Ahlers ST. Food Chem (Oxf). 2021 Jun 10;3:100029. doi: 10.1016/j.fochms.2021.100029. eCollection 2021 Dec 30. PMID: 35415644 Free PMC article.
Nutrition, metabolism, and epigenetics: pathways of circadian reprogramming.  Sato T, Sassone-Corsi P. EMBO Rep. 2022 Apr 12:e52412. doi: 10.15252/embr.202152412. Online ahead of print. PMID: 35412705 Review.
Efficacy of Nutritional Strategies on the Improvement of the Performance and Health of the Athlete: A Systematic Review.  Perez-Montilla JJ, Cuevas-Cervera M, Gonzalez-Muñoz A, Garcia-Rios MC, Navarro-Ledesma S. Int J Environ Res Public Health. 2022 Apr 1;19(7):4240. doi: 10.3390/ijerph19074240. PMID: 35409921 Free PMC article. Review.
Ketogenic Diet Consumption Inhibited Mitochondrial One-Carbon Metabolism.  Hsu FY, Liou JY, Tang FY, Sou NL, Peng JH, Chiang EI. Int J Mol Sci. 2022 Mar 26;23(7):3650. doi: 10.3390/ijms23073650. PMID: 35409009 Free PMC article.
Ketogenic Diet and Cardiac Substrate Metabolism.  Luong TV, Abild CB, Bangshaab M, Gormsen LC, Søndergaard E. Nutrients. 2022 Mar 22;14(7):1322. doi: 10.3390/nu14071322. PMID: 35405935 Free PMC article. Review.
Prurigo pigmentosa following a ketogenic diet: a case report.  Sun HY, Sebaratnam DF Eur J Clin Nutr. 2022 Apr;76(4):624-625. doi: 10.1038/s41430-021-00987-2. Epub 2021 Jul 23. PMID: 34302133

11th April 2022

Title (click on the titles below to access to the paper) Author Trials Publisher
Effects of ketosis on cocaine-induced reinstatement in male mice.  Ródenas-González F, Blanco-Gandía MC, Miñarro J, Rodríguez-Arias M. Neurosci Lett. 2022 Apr 5;778:136619. doi: 10.1016/j.neulet.2022.136619. Online ahead of print. PMID: 35395325
Seizures and Epilepsy in Childhood.  Gogou M, Cross JH. Continuum (Minneap Minn). 2022 Apr 1;28(2):428-456. doi: 10.1212/CON.0000000000001087. PMID: 35393965
Critical remarks to the article by Khodabakhshi and colleagues reporting results from a randomized study on ketogenic diet.  Huebner J, Keinki C, Käsmann L; working group Prevention and Integrative Oncology of the German Cancer Society. Clin Nutr. 2022 Mar 25:S0261-5614(22)00079-6. doi: 10.1016/j.clnu.2022.03.004. Online ahead of print. PMID: 35393135 No abstract available.
Ketones regulate endothelial homeostasis.  Lopaschuk GD, Hess DA, Verma S. Cell Metab. 2022 Apr 5;34(4):513-515. doi: 10.1016/j.cmet.2022.03.008. PMID: 35385704
Abnormal gait and hypoglycorrhachia in a toddler with seizures.  Angeli M, Vergadi E, Niotakis G, Raissaki M, Galanakis E. Pediatr Investig. 2022 Feb 21;6(1):47-49. doi: 10.1002/ped4.12311. eCollection 2022 Mar. PMID: 35382425 Free PMC article.
Could very low-calorie ketogenic diets turn off low grade inflammation in obesity? Emerging evidence.  Barrea L, Caprio M, Watanabe M, Cammarata G, Feraco A, Muscogiuri G, Verde L, Colao A, Savastano S; and on behalf of Obesity Programs of nutrition, Education, Research and Assessment (OPERA) Group. Crit Rev Food Sci Nutr. 2022 Apr 4:1-17. doi: 10.1080/10408398.2022.2054935. Online ahead of print. PMID: 35373658
Vigabatrin-associated brain abnormalities on MRI and other neurological symptoms in patients with West syndrome.  Reyes Valenzuela G, Crespo A, Princich J, Fassulo L, Semprino M, Gallo A, Rugilo C, Pociecha J, Calvo A, Caraballo RH. Epilepsy Behav. 2022 Apr;129:108606. doi: 10.1016/j.yebeh.2022.108606. Epub 2022 Feb 15. PMID: 35180571
 Neonatal seizures as onset of Inborn Errors of Metabolism (IEMs): from diagnosis to treatment. A systematic review.  Falsaperla R, Sciuto L, La Spina L, Sciuto S, Praticò AD, Ruggieri M. Metab Brain Dis. 2021 Dec;36(8):2195-2203. doi: 10.1007/s11011-021-00798-1. Epub 2021 Aug 17. PMID: 34403026 Free PMC article. Review.
Ketone body oxidation increases cardiac endothelial cell proliferation.  Weis EM, Puchalska P, Nelson AB, Taylor J, Moll I, Hasan SS, Dewenter M, Hagenmüller M, Fleming T, Poschet G, Hotz-Wagenblatt A, Backs J, Crawford PA, Fischer A. EMBO Mol Med. 2022 Apr 7;14(4):e14753. doi: 10.15252/emmm.202114753. Epub 2022 Feb 18. PMID: 35179309
Efficacy of Ketogenic Diet for Infantile Spasms in Chinese Patients With or Without Monogenic Etiology.  Wang J, Zhang J, Yang Y, Gao K, Wu Y, Zhang Y, Jiang Y. Front Pediatr. 2022 Mar 17;10:842666. doi: 10.3389/fped.2022.842666. eCollection 2022. PMID: 35372146 Free PMC article.
Can dietary patterns prevent cognitive impairment and reduce Alzheimer’s disease risk: Exploring the underlying mechanisms of effects.  Chu CQ, Yu LL, Qi GY, Mi YS, Wu WQ, Lee YK, Zhai QX, Tian FW, Chen W. Neurosci Biobehav Rev. 2022 Apr;135:104556. doi: 10.1016/j.neubiorev.2022.104556. Epub 2022 Feb 3. PMID: 35122783 Review.

4th April 2022

Title (click on the titles below to access to the paper) Author Trials Publisher
Comprehensive nutrient consumption estimation and metabolic profiling during ketogenic diet and relationship with myocardial glucose uptake on FDG-PET.  Selvaraj S, Seidelmann SB, Soni M, Bhattaru A, Margulies KB, Shah SH, Dugyala S, Qian C, Pryma DA, Arany Z, Kelly DP, Chirinos JA, Bravo PE. Eur Heart J Cardiovasc Imaging. 2022 Apr 2:jeac031. doi: 10.1093/ehjci/jeac031. Online ahead of print. PMID: 35366303
The metabolic basis of epilepsy.  Rho JM, Boison D. Nat Rev Neurol. 2022 Mar 31. doi: 10.1038/s41582-022-00651-8. Online ahead of print. PMID: 35361967 Review.
Efficacy and Safety of Diet Therapies in Children With Autism Spectrum Disorder: A Systematic Literature Review and Meta-Analysis.  Yu Y, Huang J, Chen X, Fu J, Wang X, Pu L, Gu C, Cai C. Front Neurol. 2022 Mar 14;13:844117. doi: 10.3389/fneur.2022.844117. eCollection 2022. PMID: 35359629 Free PMC article.
Fighting autoinflammation in FIRES: The role of interleukins and early immunomodulation.  Perulli M, Cicala G, Turrini I, Musto E, Quintiliani M, Gambardella ML, Pulitanò SM, Bompard S, Staccioli S, Carmillo L, Di Sante G, Ria F, Veredice C, Contaldo I, Battaglia D. Epilepsy Behav Rep. 2022 Feb 22;18:100531. doi: 10.1016/j.ebr.2022.100531. eCollection 2022. PMID: 35356746 Free PMC article.
It’s What and When You Eat: An Overview of Transcriptional and Epigenetic Responses to Dietary Perturbations in Pancreatic Islets.  Brown MR, Matveyenko AV. Front Endocrinol (Lausanne). 2022 Mar 10;13:842603. doi: 10.3389/fendo.2022.842603. eCollection 2022. PMID: 35355560 Free PMC article. Review.
Beta-hydroxybutyrate suppresses hepatic production of the ghrelin receptor antagonist, LEAP2.  Holm S, Husted AS, Skov LJ, Morville TH, Hagemann CA, Jorsal T, Dall M, Jakobsen A, Klein AB, Treebak JT, Knop FK, Schwartz TW, Clemmensen C, Holst B. Endocrinology. 2022 Mar 30:bqac038. doi: 10.1210/endocr/bqac038. Online ahead of print. PMID: 35352108
Online Accurate Detection of Breath Acetone Using Metal Oxide Semiconductor Gas Sensor and Diffusive Gas Separation.  Dong H, Qian L, Cui Y, Zheng X, Cheng C, Cao Q, Xu F, Wang J, Chen X, Wang D. Front Bioeng Biotechnol. 2022 Mar 8;10:861950. doi: 10.3389/fbioe.2022.861950. eCollection 2022. PMID: 35350181 Free PMC article.
Comparison of the Impact of the Mediterranean Diet, Anti-Inflammatory Diet, Seventh-Day Adventist Diet, and Ketogenic Diet Relative to Cognition and Cognitive Decline.  To J, Shao ZY, Gandawidjaja M, Tabibi T, Grysman N, Grossberg GT. Curr Nutr Rep. 2022 Mar 26. doi: 10.1007/s13668-022-00407-2. Online ahead of print. PMID: 35347664 Review.
Mild cognitive impairment: when nutrition helps brain energy rescue-a report from the EuGMS 2020 Congress.  Cunnane SC, Sieber CC, Swerdlow RH, Cruz-Jentoft AJ. Eur Geriatr Med. 2021 Dec;12(6):1285-1292. doi: 10.1007/s41999-021-00534-z. Epub 2021 Jul 5. PMID: 34227053 Free PMC article. Review.
Seizure modulation by the gut microbiota and tryptophan-kynurenine metabolism in an animal model of infantile spasms.  Mu C, Choudhary A, Mayengbam S, Barrett KT, Rho JM, Shearer J, Scantlebury MH. EBioMedicine. 2022 Feb;76:103833. doi: 10.1016/j.ebiom.2022.103833. Epub 2022 Jan 25. PMID: 35090836 Free PMC article.
[The ketogenic diet: history, mechanism of action, indications and contraindications].  Ivannikova EV, Altashina MA, Troshina EA. Probl Endokrinol (Mosk). 2021 Nov 3;68(1):49-72. doi: 10.14341/probl12724. PMID: 35262297 Russian.
Ketogenic diet ameliorates lipid dysregulation in type 2 diabetic mice by downregulating hepatic pescadillo 1.  Zhou J, Lu Y, Jia Y, Lu J, Jiang Z, Chen K. Mol Med. 2022 Jan 3;28(1):1. doi: 10.1186/s10020-021-00429-6. PMID: 34979900 Free PMC article.

28th March 2022

Title (click on the titles below to access to the paper) Author Trials Publisher
About gladiators and a sacred disease.  Kattner AA. Biomed J. 2022 Mar 23:S2319-4170(22)00035-X. doi: 10.1016/j.bj.2022.03.006. Online ahead of print. PMID: 35339730
The gut microbiome and the ketogenic diet: A pathway towards treatment optimization in infantile spasms.  McCafferty C. EBioMedicine. 2022 Mar 23;78:103924. doi: 10.1016/j.ebiom.2022.103924. Online ahead of print. PMID: 35339095 Free PMC article. No abstract available.
Serum metabolomic analysis of men on a low-carbohydrate diet for biochemically recurrent prostate cancer reveals the potential role of ketogenesis to slow tumor growth: a secondary analysis of the CAPS2 diet trial.  Chi JT, Lin PH, Tolstikov V, Howard L, Chen EY, Bussberg V, Greenwood B, Narain NR, Kiebish MA, Freedland SJ. Prostate Cancer Prostatic Dis. 2022 Mar 25. doi: 10.1038/s41391-022-00525-6. Online ahead of print. PMID: 35338353
Metabolic reprogramming in astrocytes results in neuronal dysfunction in intellectual disability.  Zhang H, Zheng Q, Guo T, Zhang S, Zheng S, Wang R, Deng Q, Yang G, Zhang S, Tang L, Qi Q, Zhu L, Zhang XF, Luo H, Zhang X, Sun H, Gao Y, Zhang H, Zhou Y, Han A, Zhang CS, Xu H, Wang X. Mol Psychiatry. 2022 Mar 25. doi: 10.1038/s41380-022-01521-x. Online ahead of print. PMID: 35338313
Ketogenic Effects of Multiple Doses of a Medium Chain Triglycerides Enriched Ketogenic Formula in Healthy Men under the Ketogenic Diet: A Randomized, Double-Blinded, Placebo-Controlled Study.  Nakamura K, Hagihara K, Nagai N, Egashira R, Takeuchi M, Nakano M, Saito H, Moriguchi M, Tonari S, Watanabe S, Miyake A, Ashida K. Nutrients. 2022 Mar 12;14(6):1199. doi: 10.3390/nu14061199. PMID: 35334856 Free PMC article.
Effect of Dietary Intake Through Whole Foods on Cognitive Function: Review of Randomized Controlled Trials.  Jiwani R, Robbins R, Neri A, Renero J, Lopez E, Serra MC. Curr Nutr Rep. 2022 Mar 25. doi: 10.1007/s13668-022-00412-5. Online ahead of print. PMID: 35334104 Review.
Diagnostic and Clinical Manifestation Differences of Glucose Transporter Type 1 Deficiency Syndrome in a Family with SLC2A1 Gene Mutation.  Pawlik W, Okulewicz P, Pawlik J, Krzywińska-Zdeb E. Int J Environ Res Public Health. 2022 Mar 10;19(6):3279. doi: 10.3390/ijerph19063279. PMID: 35328965 Free PMC article.
VLCKD in Combination with Physical Exercise Preserves Skeletal Muscle Mass in Sarcopenic Obesity after Severe COVID-19 Disease: A Case Report.  Camajani E, Feraco A, Basciani S, Gnessi L, Barrea L, Armani A, Caprio M. Healthcare (Basel). 2022 Mar 19;10(3):573. doi: 10.3390/healthcare10030573. PMID: 35327051 Free PMC article.
Caloric Restriction Mimetic 2-Deoxyglucose Reduces Inflammatory Signaling in Human Astrocytes: Implications for Therapeutic Strategies Targeting Neurodegenerative Diseases.  Vallee KJ, Fields JA. Brain Sci. 2022 Feb 24;12(3):308. doi: 10.3390/brainsci12030308. PMID: 35326266 Free PMC article.
Effects of dietary components on intestinal short-chain fatty acids (SCFAs) synthesis in healthy adult persons following a ketogenic diet.  Gudan A, Skonieczna-Żydecka K, Palma J, Drozd A, Stachowska E. Rocz Panstw Zakl Hig. 2022;73(1):51-69. doi: 10.32394/rpzh.2022.0196. PMID: 35322958
Non-pharmacological treatments for pediatric refractory epilepsies.  Rotondo E, Riva A, Graziosi A, Pellegrino N, Di Battista C, Di Stefano V, Striano P. Expert Rev Neurother. 2022 Mar 23. doi: 10.1080/14737175.2022.2057847. Online ahead of print. PMID: 35320056
Effect of a Ketogenic Diet on Oxidative Posttranslational Protein Modifications and Brain Homogenate Denaturation in the Kindling Model of Epilepsy in Mice.  Andreeva-Gateva P, Sabit Z, Bakalov D, Sayiner S, Tafradjiiska-Hadjiolova R, Zaharinova S, Abarova S, Koynova R, Tenchov B. Neurochem Res. 2022 Mar 22. doi: 10.1007/s11064-022-03579-z. Online ahead of print. PMID: 35316463
Ketogenic diet impairs neurological development of neonatal rats and affects biochemical composition of maternal brains: evidence of functional recovery in pups.  Wojciech K, Zuzanna R, Piotr S, Anna C, Marzena R, Joanna C, Krzysztof J, Zuzanna S. Brain Struct Funct. 2022 Apr;227(3):1099-1113. doi: 10.1007/s00429-021-02450-1. Epub 2022 Jan 17. PMID: 35038032
Benefits of a ketogenic diet on repetitive motor behavior in mice.  Brady M, Beltramini A, Vaughan G, Bechard AR. Behav Brain Res. 2022 Mar 26;422:113748. doi: 10.1016/j.bbr.2022.113748. Epub 2022 Jan 14. PMID: 35038463
Differential effects of mTOR inhibition and dietary ketosis in a mouse model of subacute necrotizing encephalomyelopathy.  Bornstein R, James K, Stokes J, Park KY, Kayser EB, Snell J, Bard A, Chen Y, Kalume F, Johnson SC. Neurobiol Dis. 2022 Feb;163:105594. doi: 10.1016/j.nbd.2021.105594. Epub 2021 Dec 20. PMID: 34933094
Intravenous ketogenic diet therapy for neonatal-onset pyruvate dehydrogenase complex deficiency.  Inui T, Wada Y, Shibuya M, Arai-Ichinoi N, Okubo Y, Endo W, Uchida T, Togashi N, Naito E, Haginoya K. Brain Dev. 2022 Mar;44(3):244-248. doi: 10.1016/j.braindev.2021.11.005. Epub 2021 Dec 1. PMID: 34863613
KETOgenic diet therapy in patients with HEPatocellular adenoma: study protocol of a matched interventional cohort study.  Oudmaijer CAJ, Berk KA, van der Louw EJTM, de Man R, van der Lelij AJ, Hoeijmakers JHJ, IJzermans J. BMJ Open. 2022 Feb 15;12(2):e053559. doi: 10.1136/bmjopen-2021-053559. PMID: 35168973 Free PMC article.
Ketogenic diet for human diseases: the underlying mechanisms and potential for clinical implementations.  Zhu H, Bi D, Zhang Y, Kong C, Du J, Wu X, Wei Q, Qin H. Signal Transduct Target Ther. 2022 Jan 17;7(1):11. doi: 10.1038/s41392-021-00831-w. PMID: 35034957 Free PMC article. Review.
Dietary Interventions: A Promising Treatment for Polycystic Ovary Syndrome.  Che X, Chen Z, Liu M, Mo Z. Ann Nutr Metab. 2021;77(6):313-323. doi: 10.1159/000519302. Epub 2021 Oct 5. PMID: 34610596 Review.
Ketogenic diet alleviates colitis by reduction of colonic group 3 innate lymphoid cells through altering gut microbiome.  Kong C, Yan X, Liu Y, Huang L, Zhu Y, He J, Gao R, Kalady MF, Goel A, Qin H, Ma Y. Signal Transduct Target Ther. 2021 Apr 23;6(1):154. doi: 10.1038/s41392-021-00549-9. PMID: 33888680 Free PMC article.

21st March 2022

Title (click on the titles below to access to the paper) Author Trials Publisher
The Efficacy and Safety of Ketogenic Diets in Drug-Resistant Epilepsy in Children and Adolescents: a Systematic Review of Randomized Controlled Trials.  Desli E, Spilioti M, Evangeliou A, Styllas F, Magkos F, Dalamaga M. Curr Nutr Rep. 2022 Mar 18. doi: 10.1007/s13668-022-00405-4. Online ahead of print. PMID: 35303283 Review.
Paradoxical neuronal hyperexcitability in a mouse model of mitochondrial pyruvate import deficiency.  De La Rossa A, Laporte MH, Astori S, Marissal T, Montessuit S, Sheshadri P, Ramos-Fernández E, Mendez P, Khani A, Quairiaux C, Taylor EB, Rutter J, Nunes JM, Carleton A, Duchen MR, Sandi C, Martinou JC. Elife. 2022 Feb 21;11:e72595. doi: 10.7554/eLife.72595. PMID: 35188099 Free PMC article.
Status of epileptic spasms: A study of 21 children.  Caraballo R, Semprino M, Fasulo L, Reyes G, Chacón S, Gallo A, Buompadre C. Epilepsy Behav. 2022 Jan;126:108451. doi: 10.1016/j.yebeh.2021.108451. Epub 2021 Dec 1. PMID: 34864379
Hepatocyte-specific fibroblast growth factor 21 overexpression ameliorates high-fat diet-induced obesity and liver steatosis in mice.  Yano K, Yamaguchi K, Seko Y, Okishio S, Ishiba H, Tochiki N, Takahashi A, Kataoka S, Okuda K, Liu Y, Fujii H, Umemura A, Moriguchi M, Okanoue T, Itoh Y. Lab Invest. 2022 Mar;102(3):281-289. doi: 10.1038/s41374-021-00680-9. Epub 2021 Nov 3. PMID: 34732847
Effects of the Ketogenic Diet in the Treatment of Gliomas: A Systematic Review.  Sargaço B, Oliveira PA, Antunes ML, Moreira AC. Nutrients. 2022 Feb 27;14(5):1007. doi: 10.3390/nu14051007. PMID: 35267981 Free PMC article. Review.
Ketogenic Diet-induced Prurigo Pigmentosa (the “Keto Rash”): A Case Report and Literature Review.  Xiao A, Kopelman H, Shitabata P, Nami N. J Clin Aesthet Dermatol. 2021 Dec;14(12 Suppl 1):S29-S32. PMID: 35291259 Free PMC article.
Use of an mHealth Ketogenic Diet App Intervention and User Behaviors Associated With Weight Loss in Adults With Overweight or Obesity: Secondary Analysis of a Randomized Clinical Trial.  Falkenhain K, Locke SR, Lowe DA, Lee T, Singer J, Weiss EJ, Little JP. JMIR Mhealth Uhealth. 2022 Mar 14;10(3):e33940. doi: 10.2196/33940. PMID: 35285809

14th March 2022

Title (click on the titles below to access to the paper) Author Trials Publisher
 Study of paediatric patients with the clinical and biochemical phenotype of glucose transporter type 1 deficiency syndrome.  Jiménez Legido M, Cortés Ledesma C, Bernardino Cuesta B, López Marín L, Cantarín Extremera V, Pérez-Cerdá C, Pérez González B, López Martín E, González Gutiérrez-Solana L. Neurologia (Engl Ed). 2022 Mar;37(2):91-100. doi: 10.1016/j.nrleng.2018.10.023. Epub 2021 Feb 8. PMID: 35279228
Lactation ketoacidosis induced by breastfeeding while on a ketogenic diet: A case report.  Osborne KC, Oliver JJ. Am J Emerg Med. 2022 Feb 27:S0735-6757(22)00139-5. doi: 10.1016/j.ajem.2022.02.054. Online ahead of print. PMID: 35277297
The Ketogenic Diet: Is It an Answer for Sarcopenic Obesity?  Ilyas Z, Perna S, A Alalwan T, Zahid MN, Spadaccini D, Gasparri C, Peroni G, Faragli A, Alogna A, La Porta E, Ali Redha A, Negro M, Cerullo G, D’Antona G, Rondanelli M. Nutrients. 2022 Jan 30;14(3):620. doi: 10.3390/nu14030620. PMID: 35276979 Review.
The Implication of Physiological Ketosis on The Cognitive Brain: A Narrative Review.  Altayyar M, Nasser JA, Thomopoulos D, Bruneau M Jr. Nutrients. 2022 Jan 25;14(3):513. doi: 10.3390/nu14030513. PMID: 35276871 Review.
The Effect of the Ketogenic Diet on Adiponectin, Omentin and Vaspin in Children with Drug-Resistant Epilepsy.  Chyra M, Roczniak W, Świętochowska E, Dudzińska M, Oświęcimska J. Nutrients. 2022 Jan 22;14(3):479. doi: 10.3390/nu14030479. PMID: 35276837
Beneficial Effects of the Very-Low-Calorie Ketogenic Diet on the Symptoms of Male Accessory Gland Inflammation.  Condorelli RA, Aversa A, Basile L, Cannarella R, Mongioì LM, Cimino L, Perelli S, Caprio M, Cimino S, Calogero AE, La Vignera S. Nutrients. 2022 Mar 4;14(5):1081. doi: 10.3390/nu14051081. PMID: 35268056 Free PMC article.
Effects of the Ketogenic Diet in the Treatment of Gliomas: A Systematic Review.  Sargaço B, Oliveira PA, Antunes ML, Moreira AC. Nutrients. 2022 Feb 27;14(5):1007. doi: 10.3390/nu14051007. PMID: 35267981 Free PMC article. Review.
Could Dietary Modification Independent of Energy Balance Influence the Underlying Pathophysiology of Type 2 Diabetes? Implications for Type 2 Diabetes Remission.  Guess ND. Diabetes Ther. 2022 Mar 10. doi: 10.1007/s13300-022-01220-4. Online ahead of print. PMID: 35266093 Review.
[The ketogenic diet: history, mechanism of action, indications and contraindications].  Ivannikova EV, Altashina MA, Troshina EA. Probl Endokrinol (Mosk). 2021 Nov 3;68(1):49-72. doi: 10.14341/probl12724. PMID: 35262297 Russian.
Extensive Biventricular Cardiac Sarcoidosis Detected on FDG PET/CT Using a 72-Hour Ketogenic Diet Preparation Protocol.  Lu Y. Clin Nucl Med. 2022 Mar 8. doi: 10.1097/RLU.0000000000004119. Online ahead of print. PMID: 35261354
The efficacy of non-fasting ketogenic diet protocol in the management of intractable epilepsy in pediatric patients: a single center study from Saudi Arabia.  Alameen Ali H, Muthaffar O, AlKarim N, Kayyali H, Elmardenly A, Tamim A, Alansari H. J Int Med Res. 2022 Mar;50(3):3000605221081714. doi: 10.1177/03000605221081714. PMID: 35259998
Low-carbohydrate diets and men’s cortisol and testosterone: Systematic review and meta-analysis.  Whittaker J, Harris M. Nutr Health. 2022 Mar 7:2601060221083079. doi: 10.1177/02601060221083079. Online ahead of print. PMID: 35254136
A Review of Targeted Therapies for Monogenic Epilepsy Syndromes.  Zimmern V, Minassian B, Korff C. Front Neurol. 2022 Feb 17;13:829116. doi: 10.3389/fneur.2022.829116. eCollection 2022. PMID: 35250833 Free PMC article. Review.
Six Days of Low Carbohydrate, Not Energy Availability, Alters the Iron and Immune Response to Exercise in Elite Athletes.  McKay AKA, Peeling P, Pyne DB, Tee N, Whitfield J, Sharma AP, Heikura IA, Burke LM. Med Sci Sports Exerc. 2022 Mar 1;54(3):377-387. doi: 10.1249/MSS.0000000000002819. PMID: 34690285
Low-Carb Diets May Produce Short-Term Diabetes Remission.  Shaughnessy AF. Am Fam Physician. 2021 Jul 1;104(1):95. PMID: 34264607 No abstract available.
Ketogenic Diets for Drug-Resistant Epilepsy.  Covey C. Am Fam Physician. 2021 May 1;103(9):524-525. PMID: 33929168 No abstract available.
Study protocol on the safety and feasibility of a normocaloric ketogenic diet in people with amyotrophic lateral sclerosis.  De Marchi F, Collo A, Scognamiglio A, Cavaletto M, Bozzi Cionci N, Biroli G, Di Gioia D, Riso S, Mazzini L. Nutrition. 2022 Feb;94:111525. doi: 10.1016/j.nut.2021.111525. Epub 2021 Oct 23. PMID: 34864433

7th March 2022

Title (click on the titles below to access to the paper) Author Trials Publisher
Effects of adding a diet intervention to exercise on hip osteoarthritis pain: protocol for the ECHO randomized controlled trial.  Hall M, Hinman RS, Knox G, Spiers L, Sumithran P, Murphy NJ, McManus F, Lamb KE, Cicuittini F, Hunter DJ, Messier SP, Bennell KL. BMC Musculoskelet Disord. 2022 Mar 5;23(1):215. doi: 10.1186/s12891-022-05128-9. PMID: 35248012
A new phenotype of aldolase a deficiency in a 14 year-old boy with epilepsy and rhabdomyolysis – case report.  Santoro L, Pjetraj D, Velmishi V, Campana C, Catassi C, Dionisi-Vici C, Maiorana A. Ital J Pediatr. 2022 Mar 4;48(1):39. doi: 10.1186/s13052-022-01228-3. PMID: 35246226 Free PMC article.
Effects of very low-carbohydrate ketogenic diet on lipid metabolism in patients with type II diabetes mellitus: a meta-analysis.  Li M, Yuan J. Nutr Hosp. 2022 Mar 4. doi: 10.20960/nh.03987. Online ahead of print. PMID: 35243868 English.
Prospective control study of efficacy and influencing factors of a ketogenic diet on refractory epilepsy in children.  Feng L, Wang J, Li X, Hu Y, Hong S, Jiang L. Transl Pediatr. 2022 Jan;11(1):138-148. doi: 10.21037/tp-21-595. PMID: 35242660 Free PMC article.
Editorial: The Effect of Carbohydrate Restriction on Cancer and Metabolic Syndrome.  Elisia I, Santosa S, Popovich DG, Krystal G. Front Nutr. 2022 Feb 14;9:823302. doi: 10.3389/fnut.2022.823302. eCollection 2022. PMID: 35237644 Free PMC article. No abstract available.
PARENTERAL NUTRITION IN A GLUT1DS PATIENT FOLLOWING CLASSIC KETOGENIC DIET: IDEAL VERSUS REAL-WORLD MANAGEMENT IN AN ACUTE SURGICAL SETTING.  Varesio C, Ferraris C, Gentilino V, Brena ML, Farris G, Guglielmetti M, Marazzi C, Pasca L, Trentani C, Tagliabue A, De Giorgis V. JPEN J Parenter Enteral Nutr. 2022 Mar 1. doi: 10.1002/jpen.2361. Online ahead of print. PMID: 35233775
Ketogenic diets inhibit mitochondrial biogenesis and induce cardiac fibrosis.  Xu S, Tao H, Cao W, Cao L, Lin Y, Zhao SM, Xu W, Cao J, Zhao JY. Signal Transduct Target Ther. 2021 Feb 9;6(1):54. doi: 10.1038/s41392-020-00411-4. PMID: 33558457 Free PMC article.
Nutritional Ketosis in Parkinson’s Disease – a Review of Remaining Questions and Insights.  Choi A, Hallett M, Ehrlich D. Neurotherapeutics. 2021 Jul;18(3):1637-1649. doi: 10.1007/s13311-021-01067-w. Epub 2021 Jul 7. PMID: 34235637 Free PMC article. Review.

2nd March 2022

Title (click on the titles below to access to the paper) Author Trials Publisher
Factors associated with initiation of the modified Atkins diet in adults with drug-resistant epilepsy.  Quiroga-Padilla PJ, Briceño C, Mayor LC. Epilepsy Behav. 2022 Feb 24;129:108620. doi: 10.1016/j.yebeh.2022.108620. Online ahead of print. PMID: 35220027
Molecular Mechanisms Underlying the Bioactive Properties of a Ketogenic Diet.  Murakami M, Tognini P. Nutrients. 2022 Feb 13;14(4):782. doi: 10.3390/nu14040782. PMID: 35215432 Free PMC article. Review.
Craniotomy Complicated by Severe Metabolic Acidosis Requiring Massive Transfusion in an Infant on Ketogenic Diet Therapy for Intractable Epilepsy.  Hayes SB, Munlemvo DM, Gillis HC, Tobias JD. Int Med Case Rep J. 2022 Feb 15;15:47-54. doi: 10.2147/IMCRJ.S349974. eCollection 2022. PMID: 35210870 Free PMC article.
Adherence to Low-Carbohydrate Diets in Patients with Diabetes: A Narrative Review.  Kumar NK, Merrill JD, Carlson S, German J, Yancy WS Jr. Diabetes Metab Syndr Obes. 2022 Feb 18;15:477-498. doi: 10.2147/DMSO.S292742. eCollection 2022. PMID: 35210797 Free PMC article. Review.
Monitoring Glucose Concentrations in Children with Epilepsy on a Ketogenic Diet.  Schiller K, Avigdor T, Kortas A, Kunz M, Unterholzner G, Klingelhöfer M, Rauchenzauner M. Healthcare (Basel). 2022 Jan 27;10(2):245. doi: 10.3390/healthcare10020245. PMID: 35206860 Free PMC article.
Heart Rate Variability and Sympathetic Activity Is Modulated by Very Low-Calorie Ketogenic Diet.  Polito R, Valenzano A, Monda V, Cibelli G, Monda M, Messina G, Villano I, Messina A. Int J Environ Res Public Health. 2022 Feb 16;19(4):2253. doi: 10.3390/ijerph19042253. PMID: 35206443 Free PMC article.
3-Hydroxybutyrate Ameliorates the Progression of Diabetic Nephropathy.  Jung J, Park WY, Kim YJ, Kim M, Choe M, Jin K, Seo JH, Ha E. Antioxidants (Basel). 2022 Feb 14;11(2):381. doi: 10.3390/antiox11020381. PMID: 35204263 Free PMC article.
nEffects of ketogenic diet on cognitive functions of mice fed high-fat-high-cholesterol diet.  Lin DT, Kao NJ, Cross TL, Lee WJ, Lin SH. J Nutr Biochem. 2022 Feb 20:108974. doi: 10.1016/j.jnutbio.2022.108974. Online ahead of print. PMID: 35196576
Congress of Neurological Surgeons systematic review and evidence-based guidelines update on the role of cytotoxic chemotherapy and other cytotoxic therapies in the management of progressive glioblastoma in adults.  Germano IM, Ziu M, Wen P, Ormond DR, Olson JJ. J Neurooncol. 2022 Feb 23. doi: 10.1007/s11060-021-03900-w. Online ahead of print. PMID: 35195819 Review.
The detection of infectious endocarditis may be enhanced by a repeat FDG-PET while maintaining patients on a ketogenic diet.  Germaini M, Boursier C, Goehringer F, Selton-Suty C, Lefevre B, Roch V, Imbert L, Claudin M, Chevalier E, Marie PY. J Nucl Cardiol. 2022 Feb 22. doi: 10.1007/s12350-022-02921-w. Online ahead of print. PMID: 35194753
Assessing the landscape of STXBP1-related disorders in 534 individuals.  Xian J, Parthasarathy S, Ruggiero SM, Balagura G, Fitch E, Helbig K, Gan J, Ganesan S, Kaufman MC, Ellis CA, Lewis-Smith D, Galer P, Cunningham K, O’Brien M, Cosico M, Baker K, Darling A, Veiga de Goes F, El Achkar CM, Doering JH, Furia F, García-Cazorla Á, Gardella E, Geertjens L, Klein C, Kolesnik-Taylor A, Lammertse H, Lee J, Mackie A, Misra-Isrie M, Olson H, Sexton E, Sheidley B, Smith L, Sotero L, Stamberger H, Syrbe S, Thalwitzer KM, van Berkel A, van Haelst M, Yuskaitis C, Weckhuysen S, Prosser B, Son Rigby C, Demarest S, Pierce S, Zhang Y, Møller RS, Bruining H, Poduri A, Zara F, Verhage M, Striano P, Helbig I. Brain. 2021 Nov 23:awab327. doi: 10.1093/brain/awab327. Online ahead of print. PMID: 35190816
A systematic analysis of diet-induced nephroprotection reveals overlapping changes in cysteine catabolism.  Koehler FC, Fu CY, Späth MR, Hoyer-Allo KJR, Bohl K, Göbel H, Lackmann JW, Grundmann F, Osterholt T, Gloistein C, Steiner JD, Antebi A, Benzing T, Schermer B, Schwarz G, Burst V, Müller RU. Transl Res. 2022 Feb 18:S1931-5244(22)00023-8. doi: 10.1016/j.trsl.2022.02.003. Online ahead of print. PMID: 35189406
Paradoxical neuronal hyperexcitability in a mouse model of mitochondrial pyruvate import deficiency.  De La Rossa A, Laporte MH, Astori S, Marissal T, Montessuit S, Sheshadri P, Ramos-Fernández E, Mendez P, Khani A, Quairiaux C, Taylor EB, Rutter J, Nunes JM, Carleton A, Duchen MR, Sandi C, Martinou JC. Elife. 2022 Feb 21;11:e72595. doi: 10.7554/eLife.72595. PMID: 35188099 Free PMC article.
Dietary medium chain triglycerides for management of epilepsy: New data from human, dog, and rodent studies.  Han FY, Conboy-Schmidt L, Rybachuk G, Volk HA, Zanghi B, Pan Y, Borges K. Epilepsia. 2021 Aug;62(8):1790-1806. doi: 10.1111/epi.16972. Epub 2021 Jun 25. PMID: 34169513 Free PMC article. Review.
Effect of high-dose intravenous ascorbic acid on cancer patients following ketogenic diet.  Sebastian S, Paul A, Joby J, Saijan S, Vilapurathu JK. J Cancer Res Ther. 2021 Oct-Dec;17(6):1583-1586. doi: 10.4103/jcrt.JCRT_973_19. PMID: 34916403 Clinical Trial.
Spatially resolved isotope tracing reveals tissue metabolic activity.  Wang L, Xing X, Zeng X, Jackson SR, TeSlaa T, Al-Dalahmah O, Samarah LZ, Goodwin K, Yang L, McReynolds MR, Li X, Wolff JJ, Rabinowitz JD, Davidson SM. Nat Methods. 2022 Feb;19(2):223-230. doi: 10.1038/s41592-021-01378-y. Epub 2022 Feb 7. PMID: 35132243
MR-Spectroscopy and Survival in Mice with High Grade Glioma Undergoing Unrestricted Ketogenic Diet.  Ciusani E, Vasco C, Rizzo A, Girgenti V, Padelli F, Pellegatta S, Fariselli L, Bruzzone MG, Salmaggi A. Nutr Cancer. 2021;73(11-12):2315-2322. doi: 10.1080/01635581.2020.1822423. Epub 2020 Sep 21. PMID: 32954880

21st February 2022

Title (click on the titles below to access to the paper) Author Trials Publisher
Medium chain triglycerides (MCT): State-of-the-art on chemistry, synthesis, health benefits and applications in food industry.  Nimbkar S, Leena MM, Moses JA, Anandharamakrishnan C. Compr Rev Food Sci Food Saf. 2022 Feb 18. doi: 10.1111/1541-4337.12926. Online ahead of print. PMID: 35181994
Vigabatrin-associated brain abnormalities on MRI and other neurological symptoms in patients with West syndrome.  Reyes Valenzuela G, Crespo A, Princich J, Fassulo L, Semprino M, Gallo A, Rugilo C, Pociecha J, Calvo A, Caraballo RH. Epilepsy Behav. 2022 Feb 15;129:108606. doi: 10.1016/j.yebeh.2022.108606. Online ahead of print. PMID: 35180571
Evidence for Improved Cognitive Health with Diet: A Narrative Review.  Hong Y, Clark E, Furbish K, Maggiolo N, West E, Sylvia L. Altern Ther Health Med. 2022 Feb 18:AT6726. Online ahead of print. PMID: 35180098
Ketone body oxidation increases cardiac endothelial cell proliferation.  Weis EM, Puchalska P, Nelson AB, Taylor J, Moll I, Hasan SS, Dewenter M, Hagenmüller M, Fleming T, Poschet G, Hotz-Wagenblatt A, Backs J, Crawford PA, Fischer A. EMBO Mol Med. 2022 Feb 18:e14753. doi: 10.15252/emmm.202114753. Online ahead of print. PMID: 35179309
Effects of an low carbohydrate/healthy fat/ketogenic diet on biomarkers of health and symptoms, anxiety and depression in Parkinson’s disease: a pilot study.  Tidman MM, White D, White T. Neurodegener Dis Manag. 2022 Feb 18. doi: 10.2217/nmt-2021-0033. Online ahead of print. PMID: 35179078
Western and ketogenic diets in neurological disorders: can you tell the difference?  Habashy KJ, Ahmad F, Ibeh S, Mantash S, Kobeissy F, Issa H, Habis R, Tfaily A, Nabha S, Harati H, Reslan MA, Yehya Y, Barsa C, Shaito A, Zibara K, El-Yazbi AF, Kobeissy FH. Nutr Rev. 2022 Feb 16:nuac008. doi: 10.1093/nutrit/nuac008. Online ahead of print. PMID: 35172003
KETOgenic diet therapy in patients with HEPatocellular adenoma: study protocol of a matched interventional cohort study.  Oudmaijer CAJ, Berk KA, van der Louw EJTM, de Man R, van der Lelij AJ, Hoeijmakers JHJ, IJzermans J. BMJ Open. 2022 Feb 15;12(2):e053559. doi: 10.1136/bmjopen-2021-053559. PMID: 35168973
Ketogenic Diet for a Young Adult Patient With Chronic-Phase Febrile Infection-Related Epilepsy Syndrome.  Obara K, Ono T. Cureus. 2022 Feb 10;14(2):e22099. doi: 10.7759/cureus.22099. eCollection 2022 Feb. PMID: 35165646 Free PMC article.
Transcriptomic profile of epileptic children treated with ketogenic therapies.  Ruiz-Herrero J, Olaso-Gonzalez G, Serna E, Cañedo-Villarroya E, Correas AG, Gambini J, Gomez-Cabrera MC, Pedrón-Giner C, Vina J. J Integr Neurosci. 2022 Jan 28;21(1):31. doi: 10.31083/j.jin2101031. PMID: 35164467
The Ketogenic Diet Improves Gut-Brain Axis in a Rat Model of Irritable Bowel Syndrome: Impact on 5-HT and BDNF Systems.  Orlando A, Chimienti G, Notarnicola M, Russo F. Int J Mol Sci. 2022 Jan 20;23(3):1098. doi: 10.3390/ijms23031098. PMID: 35163022 Free PMC article.
Analysis of Factors That May Affect the Effectiveness of Ketogenic Diet Treatment in Pediatric and Adolescent Patients.  Winczewska-Wiktor A, Hirschfeld AS, Badura-Stronka M, Komasińska-Piotrowska P, Steinborn B. J Clin Med. 2022 Jan 25;11(3):606. doi: 10.3390/jcm11030606. PMID: 35160058 Free PMC article.
Fibroblast Growth Factor 21 Facilitates the Homeostatic Control of Feeding Behavior.  Wu CT, Chaffin AT, Ryan KK. J Clin Med. 2022 Jan 24;11(3):580. doi: 10.3390/jcm11030580.  PMID: 35160033 Free PMC article. Review.
Outcomes of parenteral vs enteral ketogenic diet in pediatric super-refractory status epilepticus.  Chomtho S, Uaariyapanichkul J, Chomtho K. Seizure. 2022 Feb 5;96:79-85. doi: 10.1016/j.seizure.2022.01.019. Online ahead of print.  PMID: 35158320

14th February 2022

Title (click on the titles below to access to the paper) Author Trials Publisher
Probiotics counteract hepatic steatosis caused by ketogenic diet and upregulate AMPK signaling in a model of infantile epilepsy.  Mu C, Nikpoor N, Tompkins TA, Rho JM, Scantlebury MH, Shearer J. EBioMedicine. 2022 Feb 8:103838. doi: 10.1016/j.ebiom.2022.103838. Online ahead of print. PMID: 35148983
Can the ketogenic diet lead to Wernicke’s encephalopathy?  Javaid S, Lindenberg A, Srinivasan R. J Pediatr Rehabil Med. 2022 Feb 9. doi: 10.3233/PRM-200731. Online ahead of print. PMID: 35147570
Severe Hypertriglyceridemia-Induced Necrotizing Pancreatitis Associated With Ketogenic Diet in a Well-Controlled Patient With Type 2 Diabetes Mellitus.  Chan JT, Mude PJ, Canfield W, Makhija J, Yap JEL. Cureus. 2022 Jan 2;14(1):e20879. doi: 10.7759/cureus.20879. eCollection 2022 Jan. PMID: 35145786 Free PMC article.
Ketogenic diet in pediatric seizures: a randomized controlled trial review and Meta-Analysis.  Pizzo F, Collotta AD, Di Nora A, Costanza G, Ruggieri M, Falsaperla R. Expert Rev Neurother. 2022 Feb 11. doi: 10.1080/14737175.2022.2030220. Online ahead of print. PMID: 35144527
A comparative study of the effect of a gentle ketogenic diet containing medium-chain or long-chain triglycerides on chronic sleep deprivation-induced cognitive deficiency.  Wang X, Yang Y, Xiao A, Zhang N, Miao M, Wang Z, Han J, Wen M. Food Funct. 2022 Feb 10. doi: 10.1039/d1fo04087a. Online ahead of print. PMID: 35141738
[Effect of ketogenic diet on obesity asthma].  Kong LD, Wu QP. Zhonghua Jie He He Hu Xi Za Zhi. 2022 Feb 12;45(2):222-226. doi: 10.3760/cma.j.cn112147-20210609-00410. PMID: 35135094 Review. Chinese.
The efficacy of an unrestricted cycling ketogenic diet in preclinical models of IDH wild-type and IDH mutant glioma.  Javier R, Wang W, Drumm M, McCortney K, Sarkaria JN, Horbinski C. PLoS One. 2022 Feb 8;17(2):e0257725. doi: 10.1371/journal.pone.0257725. eCollection 2022. PMID: 35134075 Free PMC article.
Spatially resolved isotope tracing reveals tissue metabolic activity.  Wang L, Xing X, Zeng X, Jackson SR, TeSlaa T, Al-Dalahmah O, Samarah LZ, Goodwin K, Yang L, McReynolds MR, Li X, Wolff JJ, Rabinowitz JD, Davidson SM. Nat Methods. 2022 Feb;19(2):223-230. doi: 10.1038/s41592-021-01378-y. Epub 2022 Feb 7. PMID: 35132243
Dietary patterns in non-alcoholic fatty liver disease (NAFLD): Stay on the straight and narrow path!  Katsiki N, Stoian AP, Rizzo M. Clin Investig Arterioscler. 2022 Feb 4:S0214-9168(21)00155-8. doi: 10.1016/j.arteri.2021.10.001. Online ahead of print. PMID: 35131122 English, Spanish.
The Effect of Ketogenic Diet on Weight Loss in Adult Patients with Cancer: A Systematic Review and Meta-Analysis of Controlled Clinical Trials.  Taftian M, Beigrezaei S, Arabi V, Salehi-Abargouei A. Nutr Cancer. 2022 Feb 7:1-13. doi: 10.1080/01635581.2021.1942081. Online ahead of print. PMID: 35129013
Keto Rash: Ketoacidosis-Induced Prurigo Pigmentosa.  Lu LY, Chen CB. Mayo Clin Proc. 2022 Jan;97(1):20-21. doi: 10.1016/j.mayocp.2021.11.019. PMID: 34996560 No abstract available.
Ketogenesis impact on liver metabolism revealed by proteomics of lysine β-hydroxybutyrylation.  Koronowski KB, Greco CM, Huang H, Kim JK, Fribourgh JL, Crosby P, Mathur L, Ren X, Partch CL, Jang C, Qiao F, Zhao Y, Sassone-Corsi P. Cell Rep. 2021 Aug 3;36(5):109487. doi: 10.1016/j.celrep.2021.109487. PMID: 34348140 Free PMC article.
Ketogenic Diets and Cardio-Metabolic Diseases.  Zhang W, Guo X, Chen L, Chen T, Yu J, Wu C, Zheng J. Front Endocrinol (Lausanne). 2021 Nov 2;12:753039. doi: 10.3389/fendo.2021.753039. eCollection 2021. PMID: 34795641 Free PMC article. Review.
Effects of ketogenic diet on cognitive function in pentylenetetrazol-kindled rats.  Wang X, Huang S, Liu Y, Li D, Dang Y, Yang L. Epilepsy Res. 2021 Feb;170:106534. doi: 10.1016/j.eplepsyres.2020.106534. Epub 2020 Dec 10. PMID: 33385944

7th February 2022

Title (click on the titles below to access to the paper) Author Trials Publisher
Can dietary patterns prevent cognitive impairment and reduce Alzheimer’s disease risk: exploring the underlying mechanisms of effects.  Chu CQ, Yu LL, Qi GY, Mi YS, Wu WQ, Lee YK, Zhai QX, Tian FW, Chen W. Neurosci Biobehav Rev. 2022 Feb 2:104556. doi: 10.1016/j.neubiorev.2022.104556. Online ahead of print. PMID: 35122783 Review.
A Low-Carbohydrate, High-Fat Ketogenic Diet Program Implemented by an Interdisciplinary Primary Care Team Improves Markers of Cardiometabolic Health in Adults With Type 2 Diabetes: A Retrospective Secondary Analysis.  Neudorf H, Mindrum M, Mindrum C, Durrer C, Little JP. Can J Diabetes. 2021 Sep 8:S1499-2671(21)00245-8. doi: 10.1016/j.jcjd.2021.09.001. Online ahead of print. PMID: 35120790 No abstract available.
Efficacy of Anti-seizure Medications, Quinidine, and Ketogenic Diet Therapy for KCNT1-Related Epilepsy and Genotype-Efficacy Correlation Analysis.  Lin Z, Sang T, Yang Y, Wu Y, Dong Y, Ji T, Zhang Y, Wu Y, Gao K, Jiang Y. Front Neurol. 2022 Jan 18;12:834971. doi: 10.3389/fneur.2021.834971. eCollection 2021. PMID: 35116000 Free PMC article.
The effect of periodic ketogenic diet on newly diagnosed overweight or obese patients with type 2 diabetes.  Li S, Lin G, Chen J, Chen Z, Xu F, Zhu F, Zhang J, Yuan S. BMC Endocr Disord. 2022 Feb 3;22(1):34. doi: 10.1186/s12902-022-00947-2. PMID: 35115003 Free PMC article.
 Efficacy and Safety of Ketone Supplementation or Ketogenic Diets for Alzheimer’s Disease: A Mini Review.  Lilamand M, Mouton-Liger F, Di Valentin E, Sànchez Ortiz M, Paquet C. Front Nutr. 2022 Jan 17;8:807970. doi: 10.3389/fnut.2021.807970. eCollection 2021. PMID: 35111799 Free PMC article. Review.
Recent Neurotherapeutic Strategies to Promote Healthy Brain Aging: Are we there yet?  Kim CK, Sachdev PS, Braidy N. Aging Dis. 2022 Feb 1;13(1):175-214. doi: 10.14336/AD.2021.0705. eCollection 2022 Feb. PMID: 35111369 Free PMC article. Review.
Medium-chain Triglyceride Ketogenic Diet as a Treatment Strategy for Adult Super-refractory Status Epilepticus.  Dutta K, Satishchandra P, Borkotokey M. Indian J Crit Care Med. 2022 Jan;26(1):139-140. doi: 10.5005/jp-journals-10071-24073. PMID: 35110860 Free PMC article.
Nutritional Deficiencies in Vegetarian, Gluten-Free, and Ketogenic Diets.  Andrewski E, Cheng K, Vanderpool C. Pediatr Rev. 2022 Feb 1;43(2):61-70. doi: 10.1542/pir.2020-004275. PMID: 35102403 Review.
De novo DYNC1H1 mutation causes infantile developmental and epileptic encephalopathy with brain malformations.  Su T, Yan Y, Hu Q, Liu Y, Xu S. Mol Genet Genomic Med. 2022 Jan 31:e1874. doi: 10.1002/mgg3.1874. Online ahead of print. PMID: 35099838
 Complementary and Alternative Medicine (CAM) use in Children with Epilepsy.  Zhu Z, Mittal R, Walser SA, Lehman E, Kumar A, Paudel S, Mainali G. J Child Neurol. 2022 Jan 31:8830738211069790. doi: 10.1177/08830738211069790. Online ahead of print. PMID: 35099320
The effect of a 6-month ketogenic medium-chain triglyceride supplement on plasma cardiometabolic and inflammatory markers in mild cognitive impairment.  Myette-Côté É, St-Pierre V, Beaulieu S, Castellano CA, Fortier M, Plourde M, Bocti C, Fulop T, Cunnane SC. Prostaglandins Leukot Essent Fatty Acids. 2021 Jun;169:102236. doi: 10.1016/j.plefa.2020.102236. Epub 2020 Dec 24. PMID: 33906081 Clinical Trial.
Dietary Approaches to Improve Efficacy and Control Side Effects of Levodopa Therapy in Parkinson’s Disease: A Systematic Review.  Boelens Keun JT, Arnoldussen IA, Vriend C, van de Rest O. Adv Nutr. 2021 Dec 1;12(6):2265-2287. doi: 10.1093/advances/nmab060. PMID: 34113965 Free PMC article.

24th January 2022

Title (click on the titles below to access to the paper) Author Trials Publisher
Phase I single center trial of ketogenic diet for adults with traumatic brain injury.  Arora N, Litofsky NS, Golzy M, Aneja R, Staudenmyer D, Qualls K, Patil S. Clin Nutr ESPEN. 2022 Feb;47:339-345. doi: 10.1016/j.clnesp.2021.11.015. Epub 2021 Nov 16. PMID: 35063224
Specific characteristics and current diagnostic and treatment modalities performance of super refractory status epilepticus in children: A comparative study.  Briassoulis G, Stefanogianni C, Zaganas I, Raissaki M, Briassoulis P, Ilia S. Eur J Paediatr Neurol. 2022 Jan 5;37:32-39. doi: 10.1016/j.ejpn.2022.01.004. Online ahead of print. PMID: 35051734
Calorie Restriction for Cancer Prevention and Therapy: Mechanisms, Expectations, and Efficacy.  Vidoni C, Ferraresi A, Esposito A, Maheshwari C, Dhanasekaran DN, Mollace V, Isidoro C. J Cancer Prev. 2021 Dec 30;26(4):224-236. doi: 10.15430/JCP.2021.26.4.224. PMID: 35047448 Free PMC article. Review.
Ketogenic diet, African American women, and cardiovascular health: A systematic review.  Hanners A, Melnyk B, Volek J, Kelley MM. Worldviews Evid Based Nurs. 2022 Jan 19. doi: 10.1111/wvn.12561. Online ahead of print. PMID: 35044076
Benefits of a ketogenic diet on repetitive motor behavior in mice.  Brady M, Beltramini A, Vaughan G, Bechard AR. Behav Brain Res. 2022 Jan 14;422:113748. doi: 10.1016/j.bbr.2022.113748. Online ahead of print. PMID: 35038463
Ketogenic diet impairs neurological development of neonatal rats and affects biochemical composition of maternal brains: evidence of functional recovery in pups.  Wojciech K, Zuzanna R, Piotr S, Anna C, Marzena R, Joanna C, Krzysztof J, Zuzanna S. Brain Struct Funct. 2022 Jan 17. doi: 10.1007/s00429-021-02450-1. Online ahead of print. PMID: 35038032
Ketogenic Diets: Side Effects, Attitude, and Quality of Life.  Shalabi H, Alotaibi A, Alqahtani A, Alattas H, Alghamdi Z. Cureus. 2021 Dec 13;13(12):e20390. doi: 10.7759/cureus.20390. eCollection 2021 Dec. PMID: 35036220 Free PMC article.
The Relationship between Modern Fad Diets and Kidney Stone Disease: A Systematic Review of Literature.  Barghouthy Y, Corrales M, Somani B. Nutrients. 2021 Nov 26;13(12):4270. doi: 10.3390/nu13124270. PMID: 34959822 Free PMC article.
The Role of the Gut Microbiota on the Beneficial Effects of Ketogenic Diets.  Attaye I, van Oppenraaij S, Warmbrunn MV, Nieuwdorp M. Nutrients. 2021 Dec 31;14(1):191. doi: 10.3390/nu14010191. PMID: 35011071 Free PMC article.
 Inborn disorders of the malate aspartate shuttle.  Broeks MH, van Karnebeek CDM, Wanders RJA, Jans JJM, Verhoeven-Duif NM. J Inherit Metab Dis. 2021 Jul;44(4):792-808. doi: 10.1002/jimd.12402. Epub 2021 May 24. PMID: 33990986 Free PMC article. Review.

17th January 2022

Title (click on the titles below to access to the paper) Author Trials Publisher
Ketogenic diet for epilepsy: an overview of systematic review and meta-analysis.  Ruan Y, Chen L, She D, Chung Y, Ge L, Han L. Eur J Clin Nutr. 2022 Jan 13. doi: 10.1038/s41430-021-01060-8. Online ahead of print. PMID: 35027683 Review.
Efficacy of the Ketogenic Diet for Pediatric Epilepsy According to the Presence of Detectable Somatic mTOR Pathway Mutations in the Brain.  Ko A, Sim NS, Choi HS, Yang D, Kim SH, Lee JS, Kim DS, Lee JH, Kim HD, Kang HC. J Clin Neurol. 2022 Jan;18(1):71-78. doi: 10.3988/jcn.2022.18.1.71. PMID: 35021279
Decreased ovarian reserve and ovarian morphological alterations in female rat offspring exposed to a ketogenic maternal diet.  Budak Ö, Bostancı MS, Kurtoğlu E, Toprak V. Rev Assoc Med Bras (1992). 2021 Oct;67(10):1415-1420. doi: 10.1590/1806-9282.20210518. PMID: 35018968
The effect of a low carbohydrate ketogenic diet with or without exercise on postpartum weight retention, metabolic profile and physical activity performance in postpartum mice.  Hsu YJ, Huang CC, Lin CI. J Nutr Biochem. 2022 Jan 8:108941. doi: 10.1016/j.jnutbio.2022.108941. Online ahead of print. PMID: 35017000
Ketogenic diet for mitochondrial disease: potential role in treating the Multiple Symmetric Lipomatosis phenotype associated with the common MT-TK genetic mutation.  Mattman A, Nadeau E, Mezei MM, Cresswell M, Zhao S, Bosdet T, Sin DD, Guenette JA, Dupuis I, Allin E, Clarke DC. Orphanet J Rare Dis. 2022 Jan 10;17(1):12. doi: 10.1186/s13023-021-02164-x. PMID: 35012599 Free PMC article. No abstract available.
The Role of the Gut Microbiota on the Beneficial Effects of Ketogenic Diets.  Attaye I, van Oppenraaij S, Warmbrunn MV, Nieuwdorp M. Nutrients. 2021 Dec 31;14(1):191. doi: 10.3390/nu14010191. PMID: 35011071 Free PMC article. Review.
Randomized Clinical Trial to Evaluate the Morphological Changes in the Adventitial Vasa Vasorum Density and Biological Markers of Endothelial Dysfunction in Subjects with Moderate Obesity Undergoing a Very Low-Calorie Ketogenic Diet.  Sánchez E, Santos MD, Nuñez-Garcia M, Bueno M, Sajoux I, Yeramian A, Lecube A. Nutrients. 2021 Dec 23;14(1):33. doi: 10.3390/nu14010033. PMID: 35010908 Free PMC article.
Ketone Supplementation: Meeting the Needs of the Brain in an Energy Crisis.  Poff AM, Moss S, Soliven M, D’Agostino DP. Front Nutr. 2021 Dec 23;8:783659. doi: 10.3389/fnut.2021.783659. eCollection 2021. PMID: 35004814 Free PMC article. Review.
Corrigendum: The Potential Roles of Very Low Calorie, Very Low Calorie Ketogenic Diets and Very Low Carbohydrate Diets on the Gut Microbiota Composition.  Rondanelli M, Gasparri C, Peroni G, Faliva MA, Naso M, Perna S, Bazire P, Sajoux I, Maugeri R, Rigon C. Front Endocrinol (Lausanne). 2021 Dec 22;12:825790. doi: 10.3389/fendo.2021.825790. eCollection 2021. PMID: 35002986 Free PMC article.
Unexplained uterine atrophy following neoadjuvant chemotherapy in fertility sparing management of cervical cancer.  Sanson C, Majer M, Pautier P, Gouy S, Morice P. Lancet. 2021 Nov 27;398(10315):e17. doi: 10.1016/S0140-6736(21)02253-4. PMID: 34838181 No abstract available.
An Israeli tuberous sclerosis cohort: the efficacy of different anti-epileptic strategies.  Shlomovitz O, Ben-Zeev B, Pleniceanu O, Greenberger S, Lahav E, Mini S, Tzadok M. Childs Nerv Syst. 2021 Dec;37(12):3827-3833. doi: 10.1007/s00381-021-05348-9. Epub 2021 Sep 7. PMID: 34491422
RNA sequencing reveals niche gene expression effects of beta-hydroxybutyrate in primary myotubes.  Ruppert PM, Deng L, Hooiveld GJ, Hangelbroek RW, Zeigerer A, Kersten S. Life Sci Alliance. 2021 Aug 18;4(10):e202101037. doi: 10.26508/lsa.202101037. Print 2021 Oct. PMID: 34407998 Free PMC article.
Evaluation of the Modified Atkins Diet for the Treatment of Epileptic Spasms Refractory to Hormonal Therapy: A Randomized Controlled Trial.  Sharma S, Goel S, Kapoor D, Garg D, Panda I, Elwadhi A, Patra B, Mukherjee SB, Pemde H. J Child Neurol. 2021 Jul;36(8):686-691. doi: 10.1177/08830738211004747. Epub 2021 Apr 9. PMID: 33834913 Clinical Trial.

10th January 2022

Title (click on the titles below to access to the paper) Author Trials Publisher
VLCKD: a real time safety study in obesity.  Barrea L, Verde L, Vetrani C, Marino F, Aprano S, Savastano S, Colao A, Muscogiuri G. J Transl Med. 2022 Jan 8;20(1):23. doi: 10.1186/s12967-021-03221-6. PMID: 34998415
A combination of ketogenic diet and voluntary exercise ameliorates anxiety and depression-like behaviors in Balb/c mice.  Gumus H, Ilgin R, Koc B, Yuksel O, Kizildag S, Guvendi G, Karakilic A, Kandis S, Hosgorler F, Ates M, Alacam H, Uysal N. Neurosci Lett. 2022 Jan 3;770:136443. doi: 10.1016/j.neulet.2021.136443. Online ahead of print. PMID: 34990761
Is autosomal dominant polycystic kidney disease an early sweet disease?  Dachy A, Decuypere JP, Vennekens R, Jouret F, Mekahli D. Pediatr Nephrol. 2022 Jan 5. doi: 10.1007/s00467-021-05406-z. Online ahead of print. PMID: 34988697 Review.
Ketogenic diet ameliorates lipid dysregulation in type 2 diabetic mice by downregulating hepatic pescadillo 1.  Zhou J, Lu Y, Jia Y, Lu J, Jiang Z, Chen K. Mol Med. 2022 Jan 3;28(1):1. doi: 10.1186/s10020-021-00429-6. PMID: 34979900 Free PMC article.
Alkaline brain pH shift in rodent lithium-pilocarpine model of epilepsy with chronic seizures.  Lu D, Ji Y, Sundaram P, Traub RD, Guan Y, Zhou J, Li T, Zhe Sun P, Luan G, Okada Y. Brain Res. 2021 May 1;1758:147345. doi: 10.1016/j.brainres.2021.147345. Epub 2021 Feb 5. PMID: 33556378

3rd January 2022

Title (click on the titles below to access to the paper) Author Trials Publisher
Microbiota and Body Weight Control: Weight Watchers Within?  Boscaini S, Leigh SJ, Lavelle A, García-Cabrerizo R, Lipuma T, Clarke G, Schellekens H, Cryan JF. Mol Metab. 2021 Dec 29:101427. doi: 10.1016/j.molmet.2021.101427. Online ahead of print. PMID: 34973469 Review.
Nutritional treatments for Alzheimer’s disease: A narrative review.  Aschettino LA, Labyak CA, Sealey-Potts C. Alzheimers Dement. 2021 Dec;17 Suppl 8:e053172. doi: 10.1002/alz.053172. PMID: 34971279
The Effect of Ketogenic Diet on Inflammatory Arthritis and Cardiovascular Health in Rheumatic Conditions: A Mini Review.  Ciaffi J, Mitselman D, Mancarella L, Brusi V, Lisi L, Ruscitti P, Cipriani P, Meliconi R, Giacomelli R, Borghi C, Ursini F. Front Med (Lausanne). 2021 Dec 14;8:792846. doi: 10.3389/fmed.2021.792846. eCollection 2021. PMID: 34970568 Free PMC article. Review.
iThe Importance of Nutrition in Pregnancy and Lactation: Lifelong Consequences.  Marshall NE, Abrams B, Barbour LA, Catalano P, Christian P, Friedman JE, Hay WW Jr, Hernandez TL, Krebs NF, Oken E, Purnell JQ, Roberts JM, Soltani H, Wallace J, Thornburg KL. Am J Obstet Gynecol. 2021 Dec 27:S0002-9378(21)02728-9. doi: 10.1016/j.ajog.2021.12.035. Online ahead of print. PMID: 34968458 Review.
Can older patients adopt and maintain a ketogenic diet? An observational study in support of clinical trials in older patients.  Almodallal Y, Cook K, Lammert LM, Lee M, Le-Rademacher JG, Jatoi A. Medicine (Baltimore). 2021 Nov 24;100(47):e28033. doi: 10.1097/MD.0000000000028033. PMID: 34964801 Free PMC article.
Effect of Ketogenic Diet on Quality of Life in Adults with Chronic Disease: A Systematic Review of Randomized Controlled Trials.  Abboud M, AlAnouti F, Georgaki E, Papandreou D. Nutrients. 2021 Dec 14;13(12):4463. doi: 10.3390/nu13124463. PMID: 34960015 Free PMC article. Review.
Diet and Anxiety: A Scoping Review.  Aucoin M, LaChance L, Naidoo U, Remy D, Shekdar T, Sayar N, Cardozo V, Rawana T, Chan I, Cooley K. Nutrients. 2021 Dec 10;13(12):4418. doi: 10.3390/nu13124418. PMID: 34959972 Free PMC article. Review.
The Relationship between Modern Fad Diets and Kidney Stone Disease: A Systematic Review of Literature.  Barghouthy Y, Corrales M, Somani B. Nutrients. 2021 Nov 26;13(12):4270. doi: 10.3390/nu13124270. PMID: 34959822 Free PMC article. Review.
Effects of a Non-Energy-Restricted Ketogenic Diet on Clinical Oral Parameters. An Exploratory Pilot Trial.  Woelber JP, Tennert C, Ernst SF, Vach K, Ratka-Krüger P, Bertz H, Urbain P. Nutrients. 2021 Nov 25;13(12):4229. doi: 10.3390/nu13124229. PMID: 34959780 Free PMC article.
Effect of Anti-Inflammatory Diets on Pain in Rheumatoid Arthritis: A Systematic Review and Meta-Analysis.  Schönenberger KA, Schüpfer AC, Gloy VL, Hasler P, Stanga Z, Kaegi-Braun N, Reber E. Nutrients. 2021 Nov 24;13(12):4221. doi: 10.3390/nu13124221. PMID: 34959772 Free PMC article. Review.
Role of ketone bodies in diabetes-induced dementia: sirtuins, insulin resistance, synaptic plasticity, mitochondrial dysfunction, and neurotransmitter.  Chung JY, Kim OY, Song J. Nutr Rev. 2021 Dec 27:nuab118. doi: 10.1093/nutrit/nuab118. Online ahead of print. PMID: 34957519
Ketogenic Diet for Obese COVID-19 Patients: Is Respiratory Disease a Contraindication? A Narrative Review of the Literature on Ketogenic Diet and Respiratory Function.  Gangitano E, Tozzi R, Mariani S, Lenzi A, Gnessi L, Lubrano C. Front Nutr. 2021 Dec 9;8:771047. doi: 10.3389/fnut.2021.771047. eCollection 2021. PMID: 34957183 Free PMC article. Review.
Case 38-2021: A 76-Year-Old Woman with Abdominal Pain, Weight Loss, and Memory Impairment.  Willett LL, Bromberg GK, Chung R, Leaf RK, Goldman RH, Dickey AK. N Engl J Med. 2021 Dec 16;385(25):2378-2388. doi: 10.1056/NEJMcpc2107354. PMID: 34910867 No abstract available.
 Effects of Mixed of a Ketogenic Diet in Overweight and Obese Women with Polycystic Ovary Syndrome.  Cincione RI, Losavio F, Ciolli F, Valenzano A, Cibelli G, Messina G, Polito R. Int J Environ Res Public Health. 2021 Nov 27;18(23):12490. doi: 10.3390/ijerph182312490. PMID: 34886216 Free PMC article.
Keto Research Papers 2021 and older