Keto Research Papers
Pinned Articles
| Title (click on the titles below to access to the paper) | Author | Trials | Publisher | Articles |
|---|---|---|---|---|
| Optimal clinical management of children receiving dietary therapies for epilepsy: Updated recommendations of the International Ketogenic Diet Study Group. | Eric H. Kossoff, Beth A. Zupec-Kania, Stephane Auvin, Karen R. Ballaban-Gil, A.G. Christina Bergqvist, Robyn Blackford et al | Epilepsia Open, 3(2):175–192, 2018doi: 10.1002/epi4.12225 | Click to view article | |
| Glut1 Deficiency Syndrome (Glut1DS): State of the art in 2020 and recommendations of the international Glut1DS study group | Joerg Klepper1 | Cigdem Akman2 | Marisa Armeno3 | Stéphane Auvin4 | Mackenzie Cervenka5 | Helen J. Cross6 et al | Epilepsia Open 2018;3(2):175–92 | Wiley Periodicals LLC on behalf of International League Against Epilepsy | Click to view article |
| What are the minimum requirements for ketogenic diet services in resource-limited regions? Recommendations from the International League Against Epilepsy Task Force for Dietary Therapy | *Eric H. Kossoff, †Nabil Al-Macki, *Mackenzie C. Cervenka, ‡Heung D. Kim, §Jianxiang Liao, ¶Katherine Megaw, et al | Epilepsia, **(*):1–6, 2015 doi: 10.1111/epi.13039 | Click to view article | |
| International Recommendations for the Management of Adults Treated with Ketogenic Diet Therapies | is a consensus paper that has been published by an expert group of practitioners that manage ketogenic dietary therapies for adults around the world. The full paper does have to be purchased at this time for $39 but we hope that in time it will become freely available. The link to gain access to the abstract and buy the paper is as follows: | Click to view article | ||
| Ketogenic diet therapy for epilepsy during pregnancy and lactation: An international survey exploring clinician perspectives | Kelly Faltersack, Tanya J. W. McDonald, Valentina De Giorgis, Bobbie Barron, Mackenzie C. Cervenka, Anita Devlin, Laura A. Healy, Magnhild Kverneland, Elles van der Louw, Mengyang Lu, Martina P. Zanaboni, Marisa Armeno, Elizabeth A. Felton | Click to view article |
18th May 2026
| Title (click on the titles below to access to the paper) | Author | Trials | Publisher |
|---|---|---|---|
| Ketogenic diet therapy for children with super-refractory status epilepticus in intensive care: International clinical practice recommendations. | Blackford R, Whiteley VJ, Hardy I, Armeno M, Bollard T, Cross JH, Eltze C, George S, Howard C, Nijstad AL, Talzzia E, Paget C, Ray S, Simpson Z, Song-Pozderac E, Szmurlo A, Tan-Smith C, Vanatta L, van der Louw E, Schoeler NE; Ketogenic Dietitians Research Network. | Epilepsia Open. 2026 May 14. doi: 10.1002/epi4.70284. Online ahead of print. | PMID: 42132666 |
| Ketogenic metabolic therapy: low-carbohydrate interventions as novel neuroprotective strategies for cognitive dysfunction in diabetes. | Xun Y, Zeng W. | Front Aging Neurosci. 2026 Apr 24;18:1777834. doi: 10.3389/fnagi.2026.1777834. eCollection 2026. | PMID: 42109909 Free PMC article. Review. |
| Metabolic, adherence, and sustainability outcomes of plant-based low-carbohydrate and ketogenic diets: A systematic review of clinical evidence. | Mazzola G, Rondanelli M, Cabrini C, Perna S. | Nutrition. 2026 Aug;148:113222. doi: 10.1016/j.nut.2026.113222. Epub 2026 Mar 24. | PMID: 42048756 Review. |
| Long term outcomes of children started on the Ketogenic diet for pediatric super refractory status epilepticus- 15 years single center experience. | Hommady R, Lowe H, Dickson J, Owusu K, Kobayashi J, Hahn C, Zak M, Hopkins S, Jain P, McKinnon N, Donner E, Sharma S. | Seizure. 2026 May;138:127-132. doi: 10.1016/j.seizure.2026.04.017. Epub 2026 Apr 16. | PMID: 42035680 |
| Rewiring the brain: Ketogenic diet and gut microbiota in nervous system development. | Jędrusik J, Setkowicz Z. | Nutrition. 2026 Aug;148:113106. doi: 10.1016/j.nut.2026.113106. Epub 2026 Jan 10. | PMID: 42030577 Review. |
11th May 2026
| Title (click on the titles below to access to the paper) | Author | Trials | Publisher |
|---|---|---|---|
| Concurrent use of ketogenic diet therapy and cannabidiol in children and adults with epilepsy: A multicenter retrospective cohort study. |
Hinkley LM, Cervenka MC, Bessone SK, Turner Z, Kossoff EH. |
Epilepsy Res. 2026 May 5;225:107815. doi: 10.1016/j.eplepsyres.2026.107815. Online ahead of print. |
PMID: 42102520 |
| The ketogenic diet alleviates autoimmune thyroiditis caused by Th17/Treg imbalance by inhibiting the HMGB1/NLRP3 signaling pathway. |
Luo Y, Gao H, Wang M, Wang Z, Jin Z, Song N, Liu Z, Yang X. |
PLoS One. 2026 May 8;21(5):e0341564. doi: 10.1371/journal.pone.0341564. eCollection 2026. |
PMID: 42102168 Free PMC article. |
| Exploring biologically-based complementary and alternative medicine use among Irish cancer survivors: findings from a national survey. |
Scannell C, Sullivan ES, Matvienko-Sikar K, Grimes DR, Power D, Ryan A. |
Oncologist. 2026 May 8;31(6):oyag127. doi: 10.1093/oncolo/oyag127. |
PMID: 42101869 |
| Management of advanced HR-positive breast cancer using metabolically supported chemotherapy and repurposed drugs: a case report. |
Slocum AK, Tastekin D, Duraj T, Seyfried TN. |
Front Oncol. 2026 Apr 22;16:1795402. doi: 10.3389/fonc.2026.1795402. eCollection 2026. |
PMID: 42100430 Free PMC article. |
| Exploring the rise of the ketogenic dietary therapies for epilepsy in Latin America: A systematic review and meta-analysis. |
Shibaki R, de Oliveira Franco MDNS, Camargo JSL, Citro GM, Ramos EM, Bruzzone M. |
Epilepsy Res. 2026 Apr 30;225:107795. doi: 10.1016/j.eplepsyres.2026.107795. Online ahead of print. |
PMID: 42097005 |
| Gut microbiota shifts and short-chain fatty acids alterations in pediatric epilepsy patients on a Mediterranean ketogenic diet. |
Zouganeli S, Mitsou EK, Yannakoulia M, Intze E, Mountzouris KC, Fessatou S, Attilakos A, Kyriacou A, Dinopoulos A. |
Epileptic Disord. 2026 May 7. doi: 10.1002/epd2.70269. Online ahead of print. |
PMID: 42096323 |
| Can Artificial Intelligence Chatbots Plan Therapeutic Ketogenic Diets for Children With Epilepsy? |
Ajmera F, Lowe H, Dickson J, Owusu K, Zak M, Sharma S. |
J Hum Nutr Diet. 2026 Jun;39(3):e70263. doi: 10.1111/jhn.70263. |
PMID: 42092297 Free PMC article. |
| Ketoproof? A systematic classification of pharmaceutical excipients for ketogenic diet therapy. |
El Abdouni S, den Uil MG, Kafa Z, Ribeiro TS, van der Louw EJTM, Ruijgrok EJ, Nijstad AL. |
Int J Clin Pharm. 2026 May 5. doi: 10.1007/s11096-026-02156-6. Online ahead of print. |
PMID: 42084670 |
| Dietary Fat Content Influences PanIN Progression and Pancreatic Cancer Development in Mice. |
Sardarni UK, Faraoni EY, Waller AM, Strickland LN, O’Brien B, Klute KA, Cox JL, McAllister F, Bailey-Lundberg JM. |
Cancer Res Commun. 2026 May 1;6(5):1036-1047. doi: 10.1158/2767-9764.CRC-25-0777. |
PMID: 42001482 Free PMC article. |
| Modulatory role of the ketogenic diet in glial scar formation after traumatic brain injury: A Fourier transform infrared, Raman, and X-ray fluorescence microscopy study. |
Kawon K, Setkowicz Z, Czyzycki M, Rauk Z, Wilk A, Slawek A, Cieslak J, Aquilanti G, Carlomagno I, Drozdz A, Chwiej J. |
Spectrochim Acta A Mol Biomol Spectrosc. 2026 Oct 5;358:127816. doi: 10.1016/j.saa.2026.127816. Epub 2026 Mar 31. |
PMID: 41990505 |
| A ketogenic diet for the management of binge-eating disorder: a pilot study. |
Liang Y, Taylor A, Haas V, Qiu C. |
Eat Weight Disord. 2026 Mar 26;31(1):42. doi: 10.1007/s40519-026-01843-7. |
PMID: 41886041 Free PMC article. |
| The Impact of the Ketogenic Diet on the Lipid Profile in Adults: A Comprehensive Review and Meta-Regression Analysis of Randomized Controlled Trials. |
Chang C, Liu Y, Rohani P, Khodadadi N, Prabahar K, Sohouli MH. |
Endocr Pract. 2026 May;32(5):819-828. doi: 10.1016/j.eprac.2026.01.009. Epub 2026 Jan 30. |
PMID: 41621647 Review. |
4th May 2026
| Title (click on the titles below to access to the paper) | Author | Trials | Publisher |
|---|---|---|---|
| Ketogenic Diet in Children with Type 1 Diabetes: Parental Motivations and Potential Risks for Metabolic Health and Development. | Kovinthapillai R, Lan YY, Kędzia A, Niechciał E. | Nutrients. 2026 Apr 15;18(8):1244. doi: 10.3390/nu18081244. | PMID: 42075057 Review. |
| Ketogenic Diet Promotes Reward Learning by Upregulating Hippocampal CAMK2A Expression and Activating Dopamine Synaptic Signaling. | Qiao Y, Zeng Y, Chen C, Shen J, Wang Y, Pei P, Wang S. | Int J Mol Sci. 2026 Apr 17;27(8):3587. doi: 10.3390/ijms27083587. | PMID: 42074224 |
| The Role of the Ketogenic Diet in Lung Cancer: Current Evidence and Future Perspectives. | Eleftheriadou ED, Kotoulas SC, Grammatikopoulou MG, Karakousi A, Maria A, Trimpali A, Tsalampounis X, Evangelidis P, Vamvakis A, Pataka A, Spyratos D. | Cancers (Basel). 2026 Apr 17;18(8):1279. doi: 10.3390/cancers18081279. | PMID: 42073602 Review. |
| Does a low-carbohydrate diet impede endurance sports performance? Debate Consensus. | Burke LM, Noakes TD. | Am J Clin Nutr. 2026 May;123(5):101271. doi: 10.1016/j.ajcnut.2026.101271. | PMID: 42070893 Review. |
| Does a low-carbohydrate diet impede endurance sports performance? Yes. | Burke LM, Noakes TD. | Am J Clin Nutr. 2026 May;123(5):101268. doi: 10.1016/j.ajcnut.2026.101268. | PMID: 42070891 Review. |
| Movement Disorders in Developmental and Epileptic Encephalopathies. | Mohammad S, Ebrahimi-Fakhari D, Morales-Briceno H. | Mov Disord Clin Pract. 2026 May 1. doi: 10.1002/mdc3.70641. Online ahead of print. | PMID: 42068099 Review. |
| Ketogenic diet therapy for epilepsy in Australia: insights from the Pharmaceutical Benefits Scheme. | Kaul N, King L, Chen S, Kwan P, O’Brien TJ. | Intern Med J. 2026 Apr 29. doi: 10.1111/imj.70445. Online ahead of print. | PMID: 42054353 |
| Exploring Biologically-Based Complementary and Alternative Medicine Use Among Irish Cancer Survivors: Findings from a National Survey. | Scannell C, Sullivan ES, Matvienko-Sikar K, Grimes DR, Power D, Ryan A. | Oncologist. 2026 Apr 29:oyag127. doi: 10.1093/oncolo/oyag127. Online ahead of print. | PMID: 42050866 |
| Ketogenic Diets and Low-Density Lipoprotein Cholesterol in Adults With Normal Weight: An Emerging Clinical Challenge. | DiMattia ZS, Petersen KS. | J Am Heart Assoc. 2026 Apr 28:e048903. doi: 10.1161/JAHA.125.048903. Online ahead of print. | PMID: 42047192 Review. |
| Old drugs, new indications: Effectiveness of amantadine for epileptic encephalopathy in paediatric patients with spike-wave activation in sleep or refractory absence seizures. | Soto-Insuga V, González-Alguacil E, Cantarín Extremera V, García Fernández M, Gutiérrez Delicado E, Mansilla Lozano D, Duat Rodríguez A, Esteso Orduña B, García Peñas JJ. | Neurologia (Engl Ed). 2026 May;41(4):501936. doi: 10.1016/j.nrleng.2026.501936. | PMID: 42044942 |
| Impact of a ketogenic diet on clinical outcomes and immunological markers in myasthenia gravis: A randomized pilot study. | Makus B, Schulze D, Lehnerer S, Gerischer L, Stein M, Doksani P, Dusemund C, Hoffmann S, Meisel A, Stascheit F. | J Autoimmun. 2026 May;160:103562. doi: 10.1016/j.jaut.2026.103562. Epub 2026 Apr 17. | PMID: 42000538 Clinical Trial. |
| Broad-Spectrum Effects of Carbohydrate Reduction on Inflammatory and Immune Mediators in Type 2 Diabetes. | Athinarayanan SJ, Phinney SD, Adams RN, Volek JS, Thurmond DC, McKenzie AL, Roberts CGP, Ratner RE, Krauss RM, Fonseca VA. | Endocr Res. 2026 May;51(2):100-116. doi: 10.1080/07435800.2026.2659579. Epub 2026 Apr 17. | PMID: 41994946 |
| Preliminary study on ketone body metabolism in anaplastic thyroid cancer. | Wang J, Mao Y, Xuan Z, Li Z, Tang X, Yang K, Xing M, Zhu X. | Eur Thyroid J. 2026 Apr 24;15(2):ETJ250305. doi: 10.1530/ETJ-25-0305. Print 2026 Apr 1. | PMID: 41973605 Free PMC article. |
| Ketogenic diet-derived faecal microbiota transplantation improved sensorimotor gating deficits in an acute NMDA-receptor antagonist model of schizophrenia in mice. | Kraeuter AK, Sarnyai Z. | Food Funct. 2026 Apr 27;17(8):3529-3536. doi: 10.1039/d6fo00213g. | PMID: 41945453 |
| In vivo assessment of the recovery of myocardial pyruvate dehydrogenase activity following a ketogenic diet. | Chen J, Erfani Z, Elnwasany A, Al Nemri S, Park J, Huynh MT, Zaidi M, Harrison CE, Wen X, Szweda LI, Park JM. | Cardiovasc Res. 2026 Apr 28;122(6):723-733. doi: 10.1093/cvr/cvag053. | PMID: 41746829 Free PMC article. |
27th April 2026
| Title (click on the titles below to access to the paper) | Author | Trials | Publisher |
|---|---|---|---|
| Caregiver perspectives on disease burden and treatment priorities in KCNT1-related disorders. | Bryan BA, Faria V, Esposito K, Boyce D, Poliquin S, Terry I, Wright M, Abuhl A, Rosenberg A, Bearden D, West J, Drislane S. | Epilepsy Behav. 2026 Apr 24;181:111053. doi: 10.1016/j.yebeh.2026.111053. Online ahead of print. | PMID: 42034078 |
| Efficacy and safety of ketogenic diet in glioblastoma: an updated systematic review and meta-analysis. | Firdous J, Asif AE, Haris HM, Iqbal U, Khalid M, Zahid HF, Mubarika M, Abufatima IO, Amin MHJ, Hafeez S, Jabeen F, Shahzaib M, Fatima N, Kumar N, Sen S, Hassan A. | Neurol Sci. 2026 Apr 25;47(5):461. doi: 10.1007/s10072-026-09035-y. | PMID: 42032215 Free PMC article. Review. |
| A ketogenic diet sensitizes pancreatic cancer to glutamine metabolism inhibitors. | Hajihassani O, Roichman A, Boyer JA, MacArthur M, Cordova R, Loftus A, Boutros CS, Hue JJ, Naji P, Tahhan S, Gallagher P, Beegan W, Shah D, Choi J, Manzoor N, Lei S, Kim C, Rathore M, Shah I, Lebo K, Cheng H, Mudigonda A, Hunter C, Zarei M, Alibeckoff S, Ji K, Graor H, Miyagi M, Vaziri-Gohar A, Brunengraber H, Wang R, Lund PJ, Rothermel LD, Rabinowitz JD, Winter JM. | Cell Rep Med. 2026 Apr 23:102770. doi: 10.1016/j.xcrm.2026.102770. Online ahead of print. | PMID: 42030935 |
| Emergence of hypomania and mania following initiation of a ketogenic diet: case series. | Palmer CM. | Front Nutr. 2026 Apr 8;13:1815787. doi: 10.3389/fnut.2026.1815787. eCollection 2026. | PMID: 42027565 Free PMC article. |
| Ketogenic diet exacerbates DSS-induced colitis through a β-hydroxybutyrate-Thomasclavelia spiroformis-γδ17 T cell axis in mice. | Liu Y, Wu X, Chen L, Wang S, Xu J, Wang W, Yao X, Xie W, Zhong X, Li S, Li Y, Han L, Xie C, Chen L, Gonzalez FJ, Liu W. | Nat Commun. 2026 Apr 23. doi: 10.1038/s41467-026-72044-0. Online ahead of print. | PMID: 42020416 |
| Ketogenic diet regulates Uch-L1(C) to improve cerebral energy metabolism and cognitive function in Alzheimer’s disease mice. | Bao N, Zhang M, Tang M, Shen Z, Wang S, Jiang G. | Eur J Histochem. 2026 Apr 20;70(2). doi: 10.4081/ejh.2026.4548. Epub 2026 Apr 20. | PMID: 42007524 |
| Ketogenic diet attenuates late gestational sleep deprivation-induced aggression in adult offspring mice. | Zhou F, Yu X, Gong M, Yin X, Li Y, Sang Y, Liu X, Liu Y, Yan S, Song L, Zhao Y, Shi H. | Physiol Behav. 2026 Jul 1;311:115319. doi: 10.1016/j.physbeh.2026.115319. Epub 2026 Mar 26. | PMID: 41903600 |
| A Very-low-energy Fast Involves Increased Adipose Inflammatory Gene Expression: A 6-day Feeding Trial (FASTOMICS-6). | Bråtveit M, Strømland PP, Laupsa-Borge J, Skumsnes L, Dagsland VH, Kvistad S, Vogt EC, McCann A, Thorsen HL, Diamantopoulos AP, Nedrebø BG, Mellgren G, Dankel SN. | J Clin Endocrinol Metab. 2026 Apr 22;111(5):1470-1483. doi: 10.1210/clinem/dgaf570. | PMID: 41150634 Free PMC article. |
| Nutritional Interventions in Advanced Cancer: Scoping Review. | Aktas A, Thomas S, Barrett M, Sui J, Waldman J, Kenny C, Eustice-Cook J, Kadakia KC, Walsh D. | Am J Hosp Palliat Care. 2026 Jun;43(6):668-688. doi: 10.1177/10499091251335249. Epub 2025 Apr 25. | PMID: 40275738 |
| Link between emotional and external eating behaviors, peripheral neuropeptide Y, and β-hydroxybutyrate in participants with obesity on 12-week ketogenic diet. | Černelič-Bizjak M, Kenig S, Petelin A, Jenko-Pražnikar Z, Mohorko N. | Nutr Health. 2026 Mar;32(2):555-562. doi: 10.1177/02601060231154464. Epub 2023 Feb 3. | PMID: 36734124 Free PMC article. |
20th April 2026
| Title (click on the titles below to access to the paper) | Author | Trials | Publisher |
|---|---|---|---|
| DIET-INDUCED RESOLUTION OF MACULAR OEDEMA FOLLOWING REMISSION OF TYPE 2 DIABETES MELLITUS IN A PATIENT UNDERGOING THERAPEUTIC CARBOHYDRATE REDUCTION. | Hains LR, Bacchi S, Martin R, Onn Chan W, Muecke JS. | Retin Cases Brief Rep. 2025 Sep;19(5):668-670. doi: 10.1097/ICB.0000000000001614. | PMID: 41995406 |
| PURA-Related Neurodevelopmental Disorder: A Comprehensive Clinical Review of Genetics, Phenotype, and Emerging Therapeutic Strategies. | Afshar S, Ahmed W, Çelik EÖ, Younis SS, Campbell C, Potluri YKR, Kaur J, Meda DS, Manjari KK, Khachikian A, Leena J, Rai M. | Cureus. 2026 Mar 13;18(3):e105181. doi: 10.7759/cureus.105181. eCollection 2026 Mar. | PMID: 41978590 Free PMC article. Review. |
| Divergent Liver and Kidney Metabolic Responses to Ketogenic, High-Fat, and Sucrose-Enriched Diets in Mice. | Grillo G, Vega N, Zaczek A, Selmi A, Chanon S, Vieille Marchiset A, Santillo A, Balcerczyk A, Strigini M, Pirola L. | Nutrients. 2026 Apr 1;18(7):1141. doi: 10.3390/nu18071141. | PMID: 41978191 Free PMC article. |
| Targeting Insulin Resistance Through Nutrition: Pathophysiological Insights and Dietary Interventions. | Caretto A, Zanardini A, Frontino G, Pedone E. | Nutrients. 2026 Mar 31;18(7):1119. doi: 10.3390/nu18071119. | PMID: 41978168 Free PMC article. Review. |
| Short-Term Associations Between Fat-Free Mass Preservation and Glycaemic Markers During Tirzepatide Therapy: A Secondary Exploratory Analysis. | Schiavo L, Santella B, Mingo M, Rossetti G, Orio M, Cobellis L, Cobellis F, Pilone V. | Nutrients. 2026 Mar 29;18(7):1092. doi: 10.3390/nu18071092. | PMID: 41978142 Free PMC article. |
| Ketogenic Diet and Brain Health: Cerebrovascular Mechanisms, Neuroprotection, and Translational Implications. | Mózes N, Fehér Á, Csípő T, Fazekas-Pongor V, Lipécz Á, Major D, Lehoczki A, Dósa N, Pártos K, Csík B, Yi HW, Kaposvári C, Horváth K, Fekete M. | Nutrients. 2026 Mar 29;18(7):1091. doi: 10.3390/nu18071091. | PMID: 41978141 Free PMC article. Review. |
| The Ketogenic Diet and Potential Micronutrient Risks in Drug-Resistant Epilepsy Management: A Literature Review. | Singh B, Botten P, Richardson KP, Weaver C, Purohit S. | Nutrients. 2026 Mar 27;18(7):1081. doi: 10.3390/nu18071081. | PMID: 41978131 Free PMC article. Review. |
| American Epilepsy Society Clinical Practice Guideline: Infantile Epilepsy. | Freedman D, Babatunde I, Morgan RL, Abu-Sawwa R, Albert D, Behbahani M, Chapman K, Fecske E, Gaillard WD, Jones M, Meskis MA, Myers LS, Nye K, Oluigbo C, Pfeifer HH, Shellhaas RA, Thompson L, Weiner HL, Wusthoff CJ, Yozawitz E. | Epilepsy Curr. 2026 Apr 8:15357597261433266. doi: 10.1177/15357597261433266. Online ahead of print. | PMID: 41969626 Free PMC article. Review. |
13th April 2026
| Title (click on the titles below to access to the paper) | Author | Trials | Publisher |
|---|---|---|---|
| Clinical and laboratory outcomes of ketogenic versus glycine-restricted diet in nonketotic hyperglycinemia: A comparative study. | Bozacı AE, Erdal İ, Öner G, Clark ÖA, Köken ÖY, Soyuçen E. | Mol Genet Metab. 2026 Apr 7;148(2):110118. doi: 10.1016/j.ymgme.2026.110118. Online ahead of print. | PMID: 41966573 |
| Ketogenic metabolic therapy as a candidate adjunct for CBTp delivery in schizophrenia spectrum disorders. | Laurent N. | Front Psychol. 2026 Mar 25;17:1775511. doi: 10.3389/fpsyg.2026.1775511. eCollection 2026. | PMID: 41960260 Free PMC article. |
| Effect of glucose on medium chain triglyceride induced ketosis in healthy adults in a randomized, double-blind, controlled study. | Frenser M, Fobker M, Feuerborn RA, Marquardt T, Fischer T. | Sci Rep. 2026 Apr 9;16(1):12049. doi: 10.1038/s41598-026-47702-4. | PMID: 41957196 Free PMC article. Clinical Trial. |
| Ketogenic diet causes bone loss in growing and adult mice and reduces the skeletal response to exercise. | Osipov B, Robison L, Hanel J, Orr SV, Lin YY, Buxton A, Rahmati M, Tseng MC, Renato MR, Shenoy R, Bhat AS, Saiz A, Ferguson VL, Loots GG, Christiansen BA. | Bone. 2026 Jun;207:117854. doi: 10.1016/j.bone.2026.117854. Epub 2026 Mar 9. | PMID: 41812964 |
| Ketogenic diet modulates AMPK-mTOR pathway in breast cancer. | Luo Y, Li J, Yang Y, Yan L, Huang Z, Chen L, Zhao L, Wang J, Yang Y, Liu X, Yang X. | J Nutr Biochem. 2026 Jul;153:110312. doi: 10.1016/j.jnutbio.2026.110312. Epub 2026 Feb 11. | PMID: 41688032 |
| Sex-dependent protective effects of a ketogenic diet following prenatal stress exposure: Evidence from adolescent rats. | Begni V, Marchesin A, Orso R, Creutzberg KC, Precetti F, Cattaneo A, Riva MA. | Brain Behav Immun. 2026 May;134:106301. doi: 10.1016/j.bbi.2026.106301. Epub 2026 Jan 19. | PMID: 41565082 |
| L-Shaped Relationship Between Ketogenic Diet and High-Frequency Hearing Loss. | Zeng Q, Xiao Y, Sheng M, Liu B. | Laryngoscope. 2026 May;136(5):2299-2308. doi: 10.1002/lary.70287. Epub 2025 Nov 28. | PMID: 41311202 |
30th March 2026
| Title (click on the titles below to access to the paper) | Author | Trials | Publisher |
|---|---|---|---|
| Efficacy, safety, and growth outcomes of ketogenic diet therapy in children under two years of age. | Yavuz M, Yılmaz Ü, Gülağız F, Güzin Y, Pekuz S, Ünalp A. | Eur J Paediatr Neurol. 2026 Mar 27;61:68-77. doi: 10.1016/j.ejpn.2026.03.007. Online ahead of print. | PMID: 41905333 |
| Targeting systemic and tumor metabolic balances with ketogenic diets enhance efficacy of therapy in FLT3-ITD acute myeloid leukemia. | Goupille L, Boudet A, Lauture L, Sahal A, Gautier-Renard G, Chu-Van E, Nguyen AL, Chollet C, Alcazar C, Bernard I, Vergez F, de Mas V, Récher C, Kaoma T, Gallipoli P, Dembitz V, Basili I, Bernardi F, Ayrault O, Joffre C, Castelli F, Colsch B, Bourgès-Abella N, Granat F, Sarry JE. | Cell Rep. 2026 Mar 28;45(4):117185. doi: 10.1016/j.celrep.2026.117185. Online ahead of print. | PMID: 41904949 |
| Sexual dimorphism shapes renal metabolic adaptation to a ketogenic diet. | Kelly ME, Hoffner LA, Ramirez CB, Anica AL, Kim J, Tong G, Kim Y, Mannepalli V, Choi W, Jang KH, Alam YH, Jung S, Le J, Lopez ML, Rubtsova VI, Bae H, Chun Y, Song WS, Tamburini IJ, Schuster VL, Anton-Culver H, Lau WL, Martinez TF, Lee G, Jang C. | Cell Rep. 2026 Mar 28;45(4):117190. doi: 10.1016/j.celrep.2026.117190. Online ahead of print. | PMID: 41904948 |
| Carnivore and Animal-Based Diets in Sport: A Critical Evaluation of Current Evidence and Future Perspectives for Precision Nutrition. | Waśkiewicz Z. | Nutrients. 2026 Mar 21;18(6):998. doi: 10.3390/nu18060998. | PMID: 41901173 Free PMC article. Review. |
| Pyruvate Dehydrogenase Complex Deficiency: A Review of Treatments and Case Series. | Betesh-Abay B, Shany E, Staretz-Chacham O, Shelef I, Azab AN. | Int J Mol Sci. 2026 Mar 17;27(6):2732. doi: 10.3390/ijms27062732. | PMID: 41898592 Free PMC article. Review. |
| The Role of Antioxidants in the Connection Between Microbiota, Neuroinflammation and Epilepsy. | Dardano DM, Serra M, Ussia S, Ritorto G, Altomare C, Macrì E, Mollace R, Savino R, Palma E, Citraro R, Muscoli C, Caroleo MC, Russo E, Mollace V, Macrì R. | Biomedicines. 2026 Feb 27;14(3):550. doi: 10.3390/biomedicines14030550. | PMID: 41898197 Free PMC article. Review. |
| Challenges in epilepsy management in the Eastern Mediterranean (Part I): Disparities in pharmacological treatment and ketogenic diet access. | Shaaban S, Al-Ramadhani R, Alkalbani L, Kurdi D, Almasaad B, Tilako A, Dhia RB, Nderbe Melom C, Al Shehhi W, AlKhaja M, Albastaki HAK, Abdulrahman A, Ibrahim A, Benkirane N, Mohsen S. | Epileptic Disord. 2026 Mar 27. doi: 10.1002/epd2.70225. Online ahead of print. | PMID: 41891746 |
| ILAE dietary treatments task force special report: Maternal ketogenic diet exposure in epilepsy pregnancy registries-A call to action. | Kverneland M, De Giorgis V, Healy L, Faltersack K, McDonald TJW, Armeno M, Cervenka MC, Devlin A. | Epilepsia Open. 2026 Mar 25. doi: 10.1002/epi4.70246. Online ahead of print. | PMID: 41878801 |
| The Effect of Carbohydrate Intake on Muscle Hypertrophy: A Systematic Review and Meta-analysis. | Henselmans M, Vårvik FT, Izquierdo M. | Sports Med. 2026 Mar;56(3):691-702. doi: 10.1007/s40279-025-02341-z. Epub 2026 Feb 19. | PMID: 41712097 Free PMC article. |
| Effect of a non-energy restricted ketogenic diet on cognition in sedentary healthy young adults. | Khattak M, Habib SH, Irfan M. | Physiol Int. 2026 Jan 20;113(1):81-96. doi: 10.1556/2060.2025.00743. Print 2026 Mar 27. | PMID: 41556984 |
| β-Hydroxybutyrate improves glymphatic system function and alleviates cerebral edema in mice after ischemic stroke. | Yu MJ, Xiong RQ, Wu JW, Li YC, Xie JX, Zhou HP, Ye GY, Chang Y, Huang KB, Pan SY. | Acta Pharmacol Sin. 2026 Apr;47(4):903-916. doi: 10.1038/s41401-025-01706-4. Epub 2026 Jan 14. | PMID: 41535708 |
| NLRP3 inflammasome blockade treats intestinal inflammation associated with chronic granulomatous disease. | Darbinian E, Mlaga KD, Aranguren M, Desjardins A, Martineau E, Massé C, Leiding JW, Poudrier J, Falcone EL. | Blood. 2026 Mar 26;147(13):1456-1469. doi: 10.1182/blood.2025029676. | PMID: 41326329 |
23rd March 2026
| Title (click on the titles below to access to the paper) | Author | Trials | Publisher |
|---|---|---|---|
| Obesity-Focused Dietary Interventions in Breast Cancer Care: A Comprehensive Review of Medical Nutrition Therapy Approaches and Efficacy in Prevention and Treatment. | Reytor-González C, Frias-Toral E, Annunziata G, Simancas-Racines D, Barrea L. | Semin Cancer Biol. 2026 Mar 18:S1044-579X(26)00032-5. doi: 10.1016/j.semcancer.2026.03.002. Online ahead of print. | PMID: 41862063 Review. |
| Ketogenic Diet and Exercise Improve Peripheral Neuropathy in a Mouse Model of Metabolic Syndrome. | Eid SA, Jaisil P, Guo K, Hayes JM, Pacut C, Rigan DM, Carter A, Teener SJ, Kim B, Kiriluk C, Lentz W, Miller CM, Webber-Davis I, McQuown H, Jang DG, Patterson A, Koubek EJ, Bridges D, Hur J, Meyer JD, Feldman EL. | Diabetes. 2026 Mar 20:db251015. doi: 10.2337/db25-1015. Online ahead of print. | PMID: 41861283 |
| A retrospective evaluation of an online group ketogenic metabolic therapy intervention on mental health outcomes. | Bellamy EL. | Front Nutr. 2026 Mar 4;13:1751564. doi: 10.3389/fnut.2026.1751564. eCollection 2026. | PMID: 41859670 Free PMC article. |
| Dietary intervention & immunity: underlying mechanisms and future directions. | Zhao J, Li X, Liang Y, Dai T, Chen C, Guo M, Zhao X, Xu L. | J Adv Res. 2026 Mar 17:S2090-1232(26)00248-1. doi: 10.1016/j.jare.2026.03.026. Online ahead of print. | PMID: 41856471 Review. |
| From Refractory Epilepsy to Neurodegeneration: Emerging Mechanistic and Clinical Insights Into the Ketogenic Diet. | Ahire C, Yadav R, Bhamare UU, Kaur G, Palkar MB. | FASEB J. 2026 Mar 31;40(6):e71609. doi: 10.1096/fj.202503317R. | PMID: 41846418 Review. |
| A personalized plant-rich, time-restricted nutritional intervention for motor and non-motor symptoms in Parkinson’s disease: A randomized controlled trial. | Tağraf B, Oğul ÖE, Yerlikaya D, Hanoğlu L. | J Parkinsons Dis. 2026 Mar;16(2):351-361. doi: 10.1177/1877718X261422067. Epub 2026 Feb 10. | PMID: 41666212 Clinical Trial. |
| A randomized safety and feasibility crossover trial of two Mediterranean-ketogenic interventions in individuals with Parkinson’s disease. | Tosefsky K, Lam JS, Wang YN, Keymanesh S, Kuan AJ, Metcalfe-Roach A, Cirstea MS, Sacheli MA, Brett Finlay B, Cohen TR, Appel-Cresswell S. | J Parkinsons Dis. 2026 Mar;16(2):332-350. doi: 10.1177/1877718X261418986. Epub 2026 Feb 4. | PMID: 41637153 Clinical Trial. |
| The central benefit of physiologically induced ketogenic states. | Giacco A, Petito G, Senese R, Moreno M, Lombardi A, Lanni A, de Lange P. | J Physiol. 2026 Mar;604(6):2430-2447. doi: 10.1113/JP287462. Epub 2025 May 5. | PMID: 40320941 Free PMC article. Review. |
9th March 2026
| Title (click on the titles below to access to the paper) | Author | Trials | Publisher |
|---|---|---|---|
| β-hydroxybutyrate Modulates Neuroinflammatory Responses and Astrocyte Reactivity in an In Vitro Model of Traumatic Brain Injury. | Rauk Z, Maciak P, Setkowicz Z, Barczyk-Woźnicka O, Romek M, Tylko G, Samiec M, Duda M. | Mol Neurobiol. 2026 Mar 8;63(1):490. doi: 10.1007/s12035-026-05759-2. | PMID: 41795770 |
| β-hydroxybutyrate enhances the metabolic fitness of CAR T cells in cancer. | Liu S, Guruprasad P, Ramasubramanian R, Madhu B, Paruzzo L, Han K, Kelly A, Shestov A, Xu HN, Carturan A, Zhou C, Amses KR, Afriat A, Litichevskiy L, Lin J, Dubowitz E, Tangal N, Zhang J, McSween A, Tan M, Stella F, Lee A, Nason S, Hua X, Schneider M, Sleeman M, Zhang Y, Gabrielli G, Yang Z, Pajarillo R, Patel R, Ghilardi G, Patel V, Joshi A, Jiang S, Jiang Y, Porazzi P, Tchou JC, Keith B, Li M, Chong E, Schuster SJ, Milone M, Rabinowitz J, O’Connor RS, Thaiss CA, Levy M, Ruella M. | Cell. 2026 Mar 6:S0092-8674(26)00169-8. doi: 10.1016/j.cell.2026.02.004. Online ahead of print. | PMID: 41794025 |
| Real-world outcomes of ketogenic diet therapy in children with drug-resistant epilepsy in a prospective cohort study. | Han R, Xu Y, Sun J, Guo Q, Du K, Dong Y, Li X, Zhang L, Chen H, Li L, Xu D, Duan J, Li B, Zhang X, Zhu C. | Sci Rep. 2026 Mar 5. doi: 10.1038/s41598-026-42913-1. Online ahead of print. | PMID: 41787059 No abstract available. |
| Ketogenic metabolic therapy for treatment-resistant post-traumatic stress disorder (PTSD): a retrospective case report. | Laurent N. | Front Nutr. 2026 Feb 17;13:1755107. doi: 10.3389/fnut.2026.1755107. eCollection 2026. | PMID: 41783812 Free PMC article. |
| The Effect of a Ketogenic Diet on Cancer: Evidence From Systematic Reviews and Meta-Analyzes. | Kamali M, Ataei Kachooei M, Aminnezhad B, Nikoei Foshtomi E, Eftekhar A, Shamsi-Goushki A, Mohammadi S, Nouri A, Akbari ME, Zendehdel M, Moradi B, Ashouri Mirsadeghi N, Bahmani P, Bakhshimoghaddam F, Bahiraie R, Abbasi H, Doaei S, Gholamalizadeh M. | Integr Cancer Ther. 2026 Jan-Dec;25:15347354261422756. doi: 10.1177/15347354261422756. Epub 2026 Mar 4. | PMID: 41782309 Free PMC article. Review. |
| Sleep Disorders in Patients With PCOS After Ketogenic Diet Intervention: An Analysis of Influencing Factors and Development of Predictive Model. | Xie M, Li J, Bai W. | Br J Hosp Med (Lond). 2026 Feb 3;87(2):50655. doi: 10.31083/BJHM50655. | PMID: 41762102 |
| The association between gut microbiota and cognitive decline: A systematic review of the literature. | Libriani S, Facchinetti G, Marti F, Tolentino Diaz MY, Sandri E. | Nutr Res. 2026 Mar;147:16-31. doi: 10.1016/j.nutres.2026.01.003. Epub 2026 Jan 12. | PMID: 41687433 Review. |
| Ketogenic diet dampens excitatory neurotransmission by shrinking synaptic vesicle pools. | Stunault MI, Deng PY, Yadav A, Periandri EM, de Luna Vitorino FN, Thomsen MB, Sponagel J, Barfield AJ, Ponce RJ, Foroughi L, Garcia BA, Egervari G, Klyachko VA, Ashrafi G. | Cell Rep. 2026 Feb 24;45(2):116945. doi: 10.1016/j.celrep.2026.116945. Epub 2026 Feb 9. | PMID: 41671086 |
| Ketogenic diet alleviates septic lung injury via microbial gut-lung axis. | Wei M, Yi X, Lin Z, Cai J, Chen S, Zhou F, Cai H, Lu X, Tang J, Shi Y, Cui L, Yang L, Jing X, Zeng Y, Wu R, Shu T, Li Y, Yang F, He Y, Zhao Z, Yang Y, Zhu W, Jiang Q, Zhang W, Tan X, Ma Z, Fan X, Ma W, Li S, Shu W, Wei H, Xiang Z, Gilbert JA, Gong S, Wang Z. | Cell Metab. 2026 Mar 3;38(3):493-511.e12. doi: 10.1016/j.cmet.2026.01.005. Epub 2026 Feb 4. | PMID: 41643678 |
| Ketogenic diet improves cognitive impairment in rats with temporal lobe epilepsy by activating the Nrf2/HO-1/GPX4 signaling axis to inhibit ferroptosis. | Yang L, Wang J, Wang X, Li B, Zhao D, Li C, Li C, Cui Y, Chen Q, Yang Y, Gu J, Hou S, Zhang L, Qiang Y. | Free Radic Biol Med. 2026 Mar 16;246:223-238. doi: 10.1016/j.freeradbiomed.2026.01.022. Epub 2026 Jan 21. | PMID: 41577149 |
| Intermittent ketogenic diet promotes Treg differentiation and alleviates Crohn’s disease via the β-hydroxybutyrate driven AHCY-DNMT1-Foxp3 axis. | Cheng S, Cheng C, Huang C, Liu C, Xun F, Jiang W, Zhao J, Wang H. | J Crohns Colitis. 2026 Feb 5;20(2):jjag003. doi: 10.1093/ecco-jcc/jjag003. | PMID: 41527294 |
| Hydroxycarboxylic Acid Receptor 2 Mediates β-hydroxybutyrate’s Antiseizure Effect in Mice. | Naderi S, Williamson J, Sun H, Joshi S, Spera RJ, Zaib S, Sharma S, Sun C, Brodovskiy A, Zawar I, Kapur J. | Ann Neurol. 2026 Mar;99(3):809-824. doi: 10.1002/ana.78098. Epub 2025 Nov 26. | PMID: 41305866 Free PMC article. |
2nd March 2026
| Title (click on the titles below to access to the paper) | Author | Trials | Publisher |
|---|---|---|---|
| Specialization challenges and improvement strategies in pediatric epilepsy diagnosis and treatment under the leadership of tertiary hospitals: A multi-center cross-sectional survey in Chongqing. | Cao K, Liu W, Jing Y, Liu Q, Wang Y, Yang S, Zhang W, Jiang L, Hu Y. | Epileptic Disord. 2026 Feb 27. doi: 10.1002/epd2.70200. Online ahead of print. | PMID: 41757792 |
| The Citric Acid Cycle Modulates Neurologic Health and Is a Therapeutic Target of Dietary and Genetic Modification in Metabolic Disease. | Fogle KJ, Lindley SK, Satterfield SL, Amsalu BA, Figura JR, Eicher SL, Scherz LA, Palladino MJ. | Genes (Basel). 2026 Feb 4;17(2):192. doi: 10.3390/genes17020192. | PMID: 41751576 Free PMC article. |
| A ketogenic diet enhances aerobic exercise adaptation and promotes muscle mitochondrial remodeling in hyperglycemic male mice. | Pattamaprapanont P, Nava RC, Grover R, Formato M, Cooney EM, Pinto AP, Alves-Wagner AB, Das A, Guan Y, Annambhotla M, Acharya S, Rivas DA, Lessard SJ. | Nat Commun. 2026 Feb 25;17(1):1656. doi: 10.1038/s41467-026-69349-5. | PMID: 41741431 Free PMC article. |
| Ketogenic diet therapy for high-grade gliomas combined with standard treatment using an angiogenesis inhibitor: An exploratory pilot study on feasibility. | Sasayama T, Tanaka K, Nagashima H, Takahashi M, Yamanishi M, Kuroda M, Tabuchi S, Hagihara K, Yamanishi S, Ikeuchi Y, Fujita Y, Iwahashi H, Hotta S, Matsunaga M, Sanada S, Muragaki Y, Nishihara M. | Neurooncol Adv. 2025 Dec 22;8(1):vdaf264. doi: 10.1093/noajnl/vdaf264. eCollection 2026 Jan-Dec. | PMID: 41727338 Free PMC article. |
| The ketogenic diet alters microbiome-metabolome profiles to improve West syndrome therapy. | Xie G, Zhou Q, Liao J, Zheng Y, Wang W, Shen K. | Pediatr Investig. 2025 Nov 19;10(1):10-24. doi: 10.1002/ped4.70027. eCollection 2026 Feb. | PMID: 41726584 Free PMC article. |
| Treatment of pediatric epilepsy. | Li J, Liu T, Liu C, Deng J, Wu S, Kuang S, Li X, Wei Z, Liang S. | Pediatr Investig. 2026 Jan 29;10(1):86-100. doi: 10.1002/ped4.70043. eCollection 2026 Feb. | PMID: 41726582 Free PMC article. Review. |
| Noninvasive Salivary Ketone Monitoring: A Ratiometric Pdot Biosensor toward Personalized Ketogenic Management. | Gong M, Wu Z, Wang S, Yi Z, Men X, Fang X, Wu C, Chen H. | Nano Lett. 2026 Feb 25;26(7):2717-2725. doi: 10.1021/acs.nanolett.5c06239. Epub 2026 Feb 13. | PMID: 41686130 |
23rd February 2026
| Title (click on the titles below to access to the paper) | Author | Trials | Publisher |
|---|---|---|---|
| Intermittent ketogenic fasting with medium-chain triglycerides improves ataxia in COQ8A-related coenzyme Q10 deficiency: A case report. | Hahn W, Erffmeier K, Schulze M, Zahnert F, Knake S, Tsalouchidou PE. | Mol Genet Metab Rep. 2026 Feb 12;46:101296. doi: 10.1016/j.ymgmr.2026.101296. eCollection 2026 Mar. | PMID: 41716779 Free PMC article. |
| Adverse events and tolerability of ketogenic diets – a systematic literature analysis. | Schopf C, Assmann M, Wolke N, Frenser M, Marquardt T, Fischer T. | BMC Nutr. 2026 Feb 20. doi: 10.1186/s40795-026-01277-5. Online ahead of print. | PMID: 41715236 |
| Ketogenic Diet as an Epigenetic Therapy in SETD1B-Related Epilepsy. | Tsang E, Gloss BS, Hayes JP, Holland AJA, Menezes MP, Branson JA, Mohammad SS, Yan JJ, Patel S, Han VX, Dale RC. | Ann Clin Transl Neurol. 2026 Feb 19. doi: 10.1002/acn3.70345. Online ahead of print. | PMID: 41714828 |
| Ketogenic diet sex-dependent effects on rat bone marrow cells during development and β-HB protection in hypoglycemia. | Truchan K, Ilnicki B, Setkowicz Z, Osyczka AM. | Sci Rep. 2026 Feb 19. doi: 10.1038/s41598-026-40169-3. Online ahead of print. | PMID: 41714780 |
| Nutritional Management of Schizophrenia: Gut-Brain Axis Mechanisms and Dietary Interventions. | Vakili O, Motamed M, Taghizadeh M, Khatami SH. | Mol Neurobiol. 2026 Feb 19;63(1):460. doi: 10.1007/s12035-026-05751-w. | PMID: 41712175 Review. |
| Knowledge and attitudes toward ketogenic dietary therapy in adults with epilepsy. | Lutz MT, Alex M, Brandhoff F, Mayer T. | Epilepsy Behav. 2026 Feb 17;177:110939. doi: 10.1016/j.yebeh.2026.110939. Online ahead of print. | PMID: 41707290 |
| | The Diet-Multiple Sclerosis Connection: Oxidative Stress and Emerging Mechanisms. | Bucciero C, Croce A, Castellano G, Beguinot F, Formisano P, Portella G, Ulianich L, Fiory F, Malfitano AM. | Mol Neurobiol. 2026 Feb 18;63(1):450. doi: 10.1007/s12035-026-05748-5. PMID: 41703223 Free | PMC article. Review. |
| Comparative analysis of senolytic drugs reveals mitochondrial determinants of efficacy and resistance. | Wakita M, Ito K, Fujii K, Sakamoto D, Mikawa T, Sugawara S, Zhou X, Park JH, Miyagawa H, Motooka D, Ogasawara E, Ishihara N, Takahashi A, Kondoh H, Hara E. | Nat Aging. 2026 Feb;6(2):316-328. doi: 10.1038/s43587-025-01057-z. Epub 2026 Jan 29. | PMID: 41611832 Free PMC article. |
| Invited: Longitudinal Assessment of Diets with Varying Carbohydrate-to-Fat Ratios and Fiber Supplementation on Immunometabolic Markers, Liver Function, and Gut Microbiome. | Goand UK, Paudel D, Koehle AM 3rd, Hao F, Nguyen LV Jr, Yalavarthi G, Tian S, Rajakaruna S, Robert CE, da Silva IV, Chassaing B, Patterson AD, Castro R, Singh V. | J Nutr. 2026 Feb;156(2):101285. doi: 10.1016/j.tjnut.2025.101285. Epub 2025 Dec 31. | PMID: 41482230 |
| Protective effects of ketogenic diet on aldosterone-induced atherosclerosis in ApoE-/- mice. | Armani A, Marzolla V, Mammi C, Vitiello L, Bellucci E, Feraco A, Gorini S, Caprio M. | J Endocrinol Invest. 2026 Feb;49(2):435-442. doi: 10.1007/s40618-025-02740-z. Epub 2025 Nov 6. | PMID: 41196563 |
16th February 2026
| Title (click on the titles below to access to the paper) | Author | Trials | Publisher |
|---|---|---|---|
| The impact of dietary interventions on liver health biomarkers in individuals with metabolic dysfunction-associated steatotic liver disease (MASLD): a systematic literature review and meta-analysis of randomized controlled trials. | Stern UM, Wagenpfeil G, Weber SN, Alqahtani SA, Michel M, Schattenberg JM. | Eur J Nutr. 2026 Feb 14;65(2):58. doi: 10.1007/s00394-025-03870-z. | PMID: 41689666 Free PMC article. Review. |
| Noninvasive Salivary Ketone Monitoring: A Ratiometric Pdot Biosensor toward Personalized Ketogenic Management. | Gong M, Wu Z, Wang S, Yi Z, Men X, Fang X, Wu C, Chen H. | Nano Lett. 2026 Feb 13. doi: 10.1021/acs.nanolett.5c06239. Online ahead of print. | PMID: 41686130 |
| Unraveling Lennox-Gastaut Syndrome: From Molecular Pathogenesis to Precision Diagnosis and Targeted Therapy Evolving Therapeutic Strategies. | Na JH, Lee YM. | Int J Mol Sci. 2026 Jan 30;27(3):1382. doi: 10.3390/ijms27031382. | PMID: 41683806 Free PMC article. Review. |
| Oxytocin, Weight Loss and Ketosis in Response to a Very-Low-Calorie Ketogenic Diet: An Exploratory Study. | Gangitano E, Rossetti R, Tozzi R, Nevi P, Masi D, Basciani S, Gandini O, Watanabe M, Curreli M, Gnessi L, Mariani S, Lubrano C. | Nutrients. 2026 Feb 1;18(3):485. doi: 10.3390/nu18030485. | PMID: 41683307 Free PMC article. |
| Effects of Aging in Combination with High-Fat or Ketogenic Diet on Skeletal Muscle Atrophy Following Denervation in C57BL/6J Mice. | Dirmontas M, Minderis P, Ratkevicius A. | Nutrients. 2026 Feb 1;18(3):478. doi: 10.3390/nu18030478. | PMID: 41683300 Free PMC article. |
| The Ketogenic Diet in Type 2 Diabetes and Obesity: A Narrative Review of Clinical Evidence. | Kilian J, Szlęzak D, Tyszka-Czochara M, Filipowicz-Popielarska E, Bronowicka-Adamska P. | Nutrients. 2026 Jan 25;18(3):397. doi: 10.3390/nu18030397. | PMID: 41683221 Free PMC article. Review. |
| The associations between epilepsy, metabolism, and their clinical implications. | Li J, Mao Y, Zhang H, Xu X. | Front Endocrinol (Lausanne). 2026 Jan 27;17:1694550. doi: 10.3389/fendo.2026.1694550. eCollection 2026. | PMID: 41675570 Free PMC article. Review. |
| Ketogenic diet dampens excitatory neurotransmission by shrinking synaptic vesicle pools. | Stunault MI, Deng PY, Yadav A, Periandri EM, de Luna Vitorino FN, Thomsen MB, Sponagel J, Barfield AJ, Ponce RJ, Foroughi L, Garcia BA, Egervari G, Klyachko VA, Ashrafi G. | Cell Rep. 2026 Feb 9;45(2):116945. doi: 10.1016/j.celrep.2026.116945. Online ahead of print. | PMID: 41671086 |
| The Interplay Between Ketogenic Diet and the Microbiota-Gut-Brain Axis in Drug-Resistant Epilepsy: A Systematic Review. | Barros TGR, Modesto JVC, Paula MCA, Rodrigues RR, Menegusse RB, Miranda VPN, Toscano ECB, Martins MV. | Nutr Rev. 2026 Feb 10:nuaf311. doi: 10.1093/nutrit/nuaf311. Online ahead of print. | PMID: 41666114 |
| Synergistic effects of a ketogenic diet and interval exercise on vascular function in obese female undergraduate students: a randomised controlled trial demonstrating accelerated improvement. | Chen J, Cao Q, Su X, Lu X. | J Health Popul Nutr. 2026 Jan 21;45(1):63. doi: 10.1186/s41043-025-01169-7. | PMID: 41566551 Free PMC article. Clinical Trial. |
| Effects of the very low-carbohydrate ketogenic diet in women with polycystic ovary syndrome: a systematic review with meta-analysis of clinical trials. | Tosatti JAG, Magalhães FMV, Gomes KB. | Br J Nutr. 2026 Jan 28;135(2):178-193. doi: 10.1017/S0007114525105692. Epub 2025 Nov 18. | PMID: 41249157 Review. |
| Motives and predictors of modified Atkins diet discontinuation as treatment of adults with drug-resistant epilepsy. | Samões R, Cavalheiro A, Tavares MM, Teixeira C, Leal B, Chaves J, Cavaco S. | Epilepsia. 2026 Jan;67(1):199-212. doi: 10.1111/epi.18657. Epub 2025 Oct 3. | PMID: 41042251 Free PMC article. |
| Fasting the Stem Cells to Boost their Metabolic Functions. | França PHM, Degasperi GR. | Curr Stem Cell Res Ther. 2025;20(10):1029-1035. doi: 10.2174/011574888X340501250210042712. | PMID: 39976034 Review. |
9th February 2026
| Title (click on the titles below to access to the paper) | Author | Trials | Publisher |
|---|---|---|---|
| Distinct effects of ketogenic and non-ketogenic weight-loss diets on hepatic steatosis and mitochondrial metabolism in MASLD. | Qadri SF, Porthan K, Dufour S, Lehtimäki TE, Petersen KF, Shulman GI, Yki-Järvinen H, Luukkonen PK. | J Hepatol. 2026 Feb 6:S0168-8278(26)00062-0. doi: 10.1016/j.jhep.2026.02.001. Online ahead of print. | PMID: 41655910 |
| Real-world outcomes of managing autosomal-dominant polycystic kidney disease using a medical food as part of a nutrition and lifestyle program to improve renal and metabolic health. | Muensterman E, Torres JA, Weimbs T. | Front Nutr. 2026 Jan 21;12:1624639. doi: 10.3389/fnut.2025.1624639. eCollection 2025. | PMID: 41648752 Free PMC article. |
| A Case Report: Effects of a ketogenic diet on PTEN mutation-associated autism spectrum disorder. | Wang Y, Guo Y, Zhu M, Zhang L, Wang L, Liu Z, Zhao Y, Yan Z, Gao J, Cao A. | Front Nutr. 2026 Jan 21;13:1721018. doi: 10.3389/fnut.2026.1721018. eCollection 2026. | PMID: 41646164 Free PMC article. |
| Efficacy differences between tocilizumab and ketogenic diet during acute phase of febrile Infection-Related epilepsy syndrome in children: A retrospective cohort study. | Yan X, He J, Cheng M, Hong S, Jiang L, Han W. | Epilepsy Behav. 2026 Feb 2;177:110898. doi: 10.1016/j.yebeh.2026.110898. Online ahead of print. | PMID: 41633319 |
| Association between ketogenic diet and cognitive function in older adults: The mediating role of neutrophil to high-density lipoprotein cholesterol ratio. | Shi Q, Hu QY, Xu CZ, Zhou J, Yin F. | Medicine (Baltimore). 2026 Jan 30;105(5):e47441. doi: 10.1097/MD.0000000000047441. | PMID: 41630286 Free PMC article. |
| Glucose transporter type 1 deficiency syndrome: Phenotypes, molecular findings, and ketogenic therapy implementation in Argentina. | Armeno ML, Massaro M, Boccoli J, Caballero E, Chacon S, Diz M, Espeche A, Fasulo L, Galarza N, Gonzalez L, Kobayashi V, Loos M, Semprino M, Veneruzzo G, Verini A, Caraballo R. | Epileptic Disord. 2026 Feb 2. doi: 10.1002/epd2.70187. Online ahead of print. | PMID: 41626780 |
| From ketogenic metabolism to targeted therapeutics: current advances in β-hydroxybutyrylation. | Hu F, Liang C, Zhang X, Xu L, Wu C, Wan S, Wang J, Wang M, Zhang D, Liu Y, Li Z, Wang X, Huang X, Xu L. | Front Immunol. 2026 Jan 15;16:1690224. doi: 10.3389/fimmu.2025.1690224. eCollection 2025. | PMID: 41624834 Free PMC article. Review. |
| Case Report: Glucose transporter 1 deficiency syndrome misdiagnosed as bacterial meningitis. | Wang M, Wang C, Shang L, Feng Y, Huang D, Li Q, Wang J, Guo H, Wang Y. | Front Pediatr. 2026 Jan 15;13:1698163. doi: 10.3389/fped.2025.1698163. eCollection 2025. | PMID: 41624815 Free PMC article. |
| Exogenous β-Hydroxybutyrate Supplementation Alleviates Ana o 3-Induced Allergic Responses. | Cheng Y, Min F, Xu X, Yu H, Gao J, Tong P, Chen H, Wu Y. | J Agric Food Chem. 2026 Feb 4;74(4):3706-3716. doi: 10.1021/acs.jafc.5c14803. Epub 2026 Jan 22. | PMID: 41572141 |
| The global research hotspots and future trends of infantile epileptic spasms syndrome: A bibliometric analysis of trends and themes. | Wang Z, Hu D, Dong X, Zhou W. | Brain Dev. 2026 Feb;48(1):104500. doi: 10.1016/j.braindev.2026.104500. Epub 2026 Jan 16. | PMID: 41546957 |
| U-shaped and linear associations of ketogenic diet with nocturia and overactive bladder: mediation roles of frailty and platelet-to-HDL-C ratio and the influence of physical activity. | Sun Y, Yin M, Zhou L. | J Health Popul Nutr. 2026 Jan 11;45(1):51. doi: 10.1186/s41043-025-01220-7. | PMID: 41521350 Free PMC article |
| Impacts of ketogenic diet intervention on cardiometabolic outcomes in obese, dysglycemic mice. | Locatelli CAA, Nguyen MA, Morrow NM, Cameron E, Trzaskalski NA, Lorenzen-Schmidt I, Morissette A, Mulvihill EE. | Cardiovasc Diabetol. 2026 Jan 3;25(1):34. doi: 10.1186/s12933-025-03046-3. | PMID: 41484888 Free PMC article. Review. |
| The Role of Carnitine Monitoring and Supplementation in Children With Epilepsy on a Ketogenic Diet. | Vail E, Turner Z, Kossoff EH. | J Child Neurol. 2026 Mar;41(3):314-320. doi: 10.1177/08830738251356537. Epub 2025 Jul 23. | PMID: 40697002 |
2nd February 2026
| Title (click on the titles below to access to the paper) | Author | Trials | Publisher |
|---|---|---|---|
| Autism spectrum disorder comorbid with epilepsy: Etiology, mechanism, and therapy. | Shan M, Yu L, Hu T, Li X, Zhang Q, Zhang H, Guo Q, Xie H, Cheng H. | Neural Regen Res. 2026 Jan 27. doi: 10.4103/NRR.NRR-D-25-00734. Online ahead of print. | PMID: 41622472 |
| Comparative efficacy of the classical ketogenic diet and modified Atkins diet in children with drug-resistant epilepsy: A systematic review and meta-analysis. | Sharaf MA, Abdelhamed MH, Salah M, Abdulbaki SGR, Ali HGA. | Seizure. 2026 Jan 24;135:77-87. doi: 10.1016/j.seizure.2026.01.014. Online ahead of print. | PMID: 41616756 Review. |
| [Super-refractory status epilepticus caused by hereditary mitochondrial disease]. | Sørensen NB, Stamenkovic K, Steffensen EH, Kofoed IR. | Ugeskr Laeger. 2026 Jan 26;188(5):V07250609. doi: 10.61409/V07250609. | PMID: 41614251 Danish. |
| Metabolic and molecular evaluation of Moringa oleifera-supplemented ketogenic meal replacement in healthy C57BL/6 mice. | Hassaan AI, Ebeed NM, Fatouh A, Elhariry H. | Sci Rep. 2026 Jan 28;16(1):4091. doi: 10.1038/s41598-025-34443-z. | PMID: 41605998 Free PMC article. |
| Efficacy and safety of antioxidants and dietary therapies for epilepsy: an umbrella meta-analysis. | Feng Y, Cai S, Wang M, Guo Y, Zhou Z, Wang R, Yang S. | Front Nutr. 2026 Jan 12;12:1723370. doi: 10.3389/fnut.2025.1723370. eCollection 2025. | PMID: 41601892 Free PMC article. |
| Carnivore Diet: A Scoping Review of the Current Evidence, Potential Benefits and Risks. | Lietz A, Dapprich J, Fischer T. | Nutrients. 2026 Jan 21;18(2):348. doi: 10.3390/nu18020348. | PMID: 41599961 Free PMC article. Review. |
| Clinical Tolerability and Safety of Ketogenic Diet in Patients with Gynecological Malignancies Undergoing Radiotherapy: Preliminary Results of a Prospective, Randomized, Open-Label Trial (KOMPARC). | Cintoni M, Autorino R, Rinaldi RM, Leonardi E, Palombaro M, Chiloiro G, De Luca V, Raoul PC, Rinninella E, Capristo E, Gasbarrini A, Gambacorta MA, Mele MC. | Nutrients. 2026 Jan 19;18(2):312. doi: 10.3390/nu18020312. | PMID: 41599926 Free PMC article. Clinical Trial. |
| Alteration in Amino Acid Metabolism After Isocaloric, Energy-Restricted Ketogenic Diet in Women with Overweight and Obesity: Randomized KETO-MINOX Trial. | Drabińska-Fois N, Majcher A, Jagielski P, Borowicz-Skoneczny S, Romaszko J. | Nutrients. 2026 Jan 18;18(2):300. doi: 10.3390/nu18020300. | PMID: 41599913 Free PMC article. Clinical Trial. |
| Clinical Impact of Ketogenic Diet. | Guarnotta V. | Nutrients. 2026 Jan 13;18(2):245. doi: 10.3390/nu18020245. | PMID: 41599858 Free PMC article. |
| Metabolic and Orexin-A Responses to Ketogenic Diet and Intermittent Fasting: A 12-Month Randomized Trial in Adults with Obesity. | Monda A, Casillo M, Allocca S, Moscatelli F, La Marra M, Monda V, Di Maio G, Vasco P, Monda M, Polito R, Messina G, Messina A. | Nutrients. 2026 Jan 12;18(2):238. doi: 10.3390/nu18020238. | PMID: 41599851 Free PMC article. Clinical Trial. |
| Towards Simplification of Ketogenic Diet in Epilepsy: Effect of Caprylic (C8) and Capric (C10) Acid on the Mitochondrial Respiratory Chain in Murine Hippocampal Neurons In Vitro. | Rühling MR, Hartmann H, Das AM. | Nutrients. 2026 Jan 9;18(2):216. doi: 10.3390/nu18020216. | PMID: 41599828 Free PMC article. |
| Diet, Physical Exercise, and Gut Microbiota Modulation in Metabolic Syndrome: A Narrative Review. | Onu A, Tutu A, Trofin DM, Onu I, Galaction AI, Onita CA, Iordan DA, Matei DV. | Life (Basel). 2026 Jan 10;16(1):98. doi: 10.3390/life16010098. | PMID: 41598253 Free PMC article. Review. |
| Ketones in Cardiovascular Health and Disease: An Updated Review. | Shrestha S, Harrison I, Dosunmu A, Song P. | Cells. 2026 Jan 14;15(2):150. doi: 10.3390/cells15020150. | PMID: 41597225 Free PMC article. Review. |
| The impact of the ketogenic diet on Alzheimer’s disease progression. | Grese Z, Naidu A, Silverglate BD, Grossberg GT. | Expert Rev Neurother. 2026 Jan 27:1-13. doi: 10.1080/14737175.2026.2621502. Online ahead of print. | PMID: 41593839 Review. |
| The effects of a very low-energy ketogenic therapy on body composition, gut microbiota and metabolites in overweight subjects. | Khazrai YM, Di Rosa C, Altomare A, Giovanetti M, Di Francesco L, Lattanzi G, Spiezia C, Simone A, Coccaro F, Costa G, Guarino MPL, Manfrini S. | Front Nutr. 2026 Jan 9;12:1714444. doi: 10.3389/fnut.2025.1714444. eCollection 2025. | PMID: 41586244 Free PMC article. |
| Medically supervised ketogenic diet as an adjunctive treatment for moderate to severe depression: A pilot study. | Brietzke E, Fabe J, Bambokian A, Breda V, Chaves C, Shelp J, Terpstra A, Koning E, Groll D, Milev R, McIntyre RS, Mansur RB, Soares CN, Gomes FA. | J Affect Disord. 2026 Apr 15;399:121079. doi: 10.1016/j.jad.2025.121079. Epub 2025 Dec 29. | PMID: 41475571 |
| Complementary mechanisms of high-carbohydrate diets and ketogenic diets restore adult hippocampal neurogenesis and cognitive function in high-fat diet induced obesity in mice. | Kwon H, Seo DS, Ahmad Y, Park S, Yoo J, Lee J, Bae HJ, Jang Y. | J Nutr Biochem. 2026 Apr;150:110245. doi: 10.1016/j.jnutbio.2025.110245. Epub 2025 Dec 29. | PMID: 41475465 |
| Ketogenic diet attenuates high fat diet induced obesity in rats: insights into hepatic and intestinal tissues. | Abo El-Magd NF, Ramadan NM, Hassan YF, Mahmoud AM, Azzam MM, Eraky SM. | J Nutr Biochem. 2026 Apr;150:110237. doi: 10.1016/j.jnutbio.2025.110237. Epub 2025 Dec 13. | PMID: 41397600 |
| Ketogenic diet and β-hydroxybutyrate inhibit HDAC1 to preserve vascular smooth muscle cell function in thoracic aortic aneurysm. | Weng X, Pan L, Ma X, Luo W, Su H, Pei Z, Dong Z, Liu L, Yang J, Gao P, Sun A. | J Adv Res. 2026 Feb;80:475-486. doi: 10.1016/j.jare.2025.05.035. Epub 2025 May 19. | PMID: 40398746 |
21st January 2026
| Title (click on the titles below to access to the paper) | Author | Trials | Publisher |
|---|---|---|---|
| Faster but less accurate: An explorative study on the effects of three weeks of ketogenic diet on cognitive functions in undergraduate students. | Serio G, Pacelli C, Piccoli C, Capitanio N, Cibelli G, Valenzano AA, Landini F, Carlucci L, Palladino P. | PLoS One. 2026 Jan 14;21(1):e0338877. doi: 10.1371/journal.pone.0338877. eCollection 2026. | PMID: 41533676 Free PMC article. |
| Metabolic adaptations and dietary preferences in mice exposed to ketogenic and high-fat high-sucrose diets. | Penna-de-Carvalho A, Nagagata BA, Guarnieri RS, Borges MMS, Teixeira LPM, Ferreira-Machado SC, Aguila MB. | Nutrition. 2026 Mar;143:113037. doi: 10.1016/j.nut.2025.113037. Epub 2025 Nov 23. | PMID: 41455458 |
| Ketogenic diet impairs NK cell cytotoxic function in colorectal cancer liver metastasis by inducing ferroptosis via suppression of the p62-Keap1-Nrf2 pathway. | Cai R, Meng Y, Ru M, Wang X, Li W, Liu X, Zhuang S, Huang Y, Diao H. | Redox Biol. 2026 Feb;89:103969. doi: 10.1016/j.redox.2025.103969. Epub 2025 Dec 10. | PMID: 41385828 Free PMC article. |
| War, diet, and PTSD in Ukrainian youth. | Halabitska I, Petakh P, Buchynskyi M, Kamyshna I, Lushchak O, Kamyshnyi O. | Sci Rep. 2025 Dec 4;16(1):1422. doi: 10.1038/s41598-025-31138-3. | PMID: 41345238 Free PMC article |
| Very low-calorie ketogenic diet reduces left ventricular mass and epicardial adipose tissue in post-menopausal women with essential hypertension and obesity: A single-center, prospective, open-label, clinical study. | Pala B, Nardoianni G, Pennazzi L, di Renzo L, Gualtieri P, Frank G, Baldi T, Barbato E, Tocci G. | Nutr Metab Cardiovasc Dis. 2026 Feb;36(2):104368. doi: 10.1016/j.numecd.2025.104368. Epub 2025 Sep 13. | PMID: 41093686 |
| Exploring the Gut-brain Axis: Microbiome Contributions to Pathophysiology of Attention Deficit Hyperactivity Disorder and Potential Therapeutic Strategies. | Phatak M, Nair B, Soni U, Pujari R. | Curr Drug Metab. 2025;26(1):1-11. doi: 10.2174/0113892002361676250325082424. | PMID: 40207768 Review. |
| Perspectives on the ketogenic diet as a non-pharmacological intervention for major depressive disorder. | Shelp J, Chaves C, Terpstra A, Koning E, Gomes FA, Fabe J, Breda V, Laurent N, Palmer C, Brietzke E. | Trends Psychiatry Psychother. 2025;47:e20240932. doi: 10.47626/2237-6089-2024-0932. Epub 2025 Mar 21. | PMID: 40117502 Review. |
12th January 2026
| Title (click on the titles below to access to the paper) | Author | Trials | Publisher |
|---|---|---|---|
| Denosumab as a treatment for pediatric hypercalcemia-a multicenter experience. | Hobbs A, Nair R, Ludwig K, Ambler GR, Munns CF. | JBMR Plus. 2025 Nov 28;10(2):ziaf171. doi: 10.1093/jbmrpl/ziaf171. eCollection 2026 Feb. | PMID: 41522662 Free PMC article. |
| Modulation of Gut Microbiome and Metabolome as One of the Potential Mechanisms of Ketogenic Diet Effect in the Treatment of Epilepsy. | Kowalcze K, Dyńka D, Klus W, Dudzińska M, Paziewska A. | Nutrients. 2025 Dec 21;18(1):31. doi: 10.3390/nu18010031. | PMID: 41515148 Free PMC article. Review. |
| Managing GLUT 1 Deficiency with the Ketogenic Diet: A Retrospective Look at Seizures, Medications, and Side Effects in a Pediatric Cohort. | Morris S, Blackford R, Lowman W, Fisher B. | J Child Neurol. 2026 Jan 9:8830738251409560. doi: 10.1177/08830738251409560. Online ahead of print. | PMID: 41512108 |
| Implementation of a ketogenic diet clinic in Mexico: A pilot program in a resource-limited setting. | Chavez-Castillo M, Hurtado-Cuan P, Soto-Blanquel MA, Jimenez-Ruiz A, Gomez-Figueroa E, Marquez-Palacios R. | Epilepsy Behav Rep. 2025 Dec 16;33:100842. doi: 10.1016/j.ebr.2025.100842. eCollection 2026 Mar. | PMID: 41509656 Free PMC article. |
| Ketogenic Diet in Super-Refractory Status Epilepticus: A Retrospective Cohort Study with Severity-Matched Controls in Critically Ill Adults. | Feil K, Kindzierski S, Single C, Geiger-Primo L, Schweikert D, Adolph M, Kegele J, Lerche H, Ziemann U, Möller L, Mengel A; IGNITE Study Group. | Neurocrit Care. 2026 Jan 8. doi: 10.1007/s12028-025-02431-w. Online ahead of print. | PMID: 41507676 |
| Mapping research landscapes: a bibliometric and visual analysis of ketogenic diet interventions in liver health (2013-2024). | Wang Y, Lu Q, Ma H, Huang J, Zhang B, Qin Y, Feng Z, Jin X. | Front Nutr. 2025 Dec 23;12:1652271. doi: 10.3389/fnut.2025.1652271. eCollection 2025. | PMID: 41502820 Free PMC article. |
| Breaking the resistance: a narrative review of the evolution from traditional drugs to precision therapies in epilepsy. | Patel T, Henna F, Ahmad A, Ahmad A, Huda NU, Aaraiz Ul Hassan S, Muhammad A, Javed A, Filal M, Iltaf A, Anwar Khalid A, Syeda ZR, Hanani C, Anand N. | Ann Med Surg (Lond). 2025 Nov 26;88(1):412-421. doi: 10.1097/MS9.0000000000004295. eCollection 2026 Jan. | PMID: 41496926 Free PMC article. Review. |
| Dietary habits, nutritional supplement use, and adherence to national dietary guidelines in patients with psoriasis. | Martin HM, Näslund-Koch C, Løvendorf MB, Bojesen SE, Kobylecki CJ, Vedel-Krogh S, Skov L. | Sci Rep. 2025 Dec 18;16(1):846. doi: 10.1038/s41598-025-30571-8. | PMID: 41413143 Free PMC article. |
| Utility of serum blood ketone levels and other risk factors for inadequate myocardial glucose suppression ketogenic FDG-PET/CT: a prospective and retrospective cohort study. | Huo YR, Gupta S, Rutherford N, Saul M, Chan MV. | Ann Nucl Med. 2026 Jan;40(1):87-95. doi: 10.1007/s12149-025-02141-5. Epub 2025 Dec 15. | PMID: 41396349 |
| Ketogenic Diets and Depression and Anxiety: A Systematic Review and Meta-Analysis. | Janssen-Aguilar R, Vije T, Peera M, Al-Shamali HF, Meshkat S, Lin Q, Lou W, Laviada-Molina H, Phillips ML, Bhat V. | JAMA Psychiatry. 2026 Jan 1;83(1):13-22. doi: 10.1001/jamapsychiatry.2025.3261. | PMID: 41191382 |
| Medium-chain triglycerides improve cognition and systemic metabolism in mouse models of Alzheimer’s disease. | M’Bra PEH, Hamilton LK, Moquin-Beaudry G, Mangahas CL, Pratesi F, Castonguay A, Mailloux S, Galoppin M, Avila Lopez J, Bernier M, Turri M, Mayhue M, Aumont A, Tetreault M, Cunnane SC, Fernandes KJL. | Brain. 2026 Jan 8;149(1):105-122. doi: 10.1093/brain/awaf267. | PMID: 40794774 Free PMC article. |
| Low-Carbohydrate Diets for the Management of Pediatric Obesity: A Systematic Review and Meta-analysis. | Fournier E, Moore H, Alghamdi ZS, Thivel D. | Nutr Rev. 2026 Feb 1;84(2):267-303. doi: 10.1093/nutrit/nuaf029. | PMID: 40233200 |
5th January 2026
| Title (click on the titles below to access to the paper) | Author | Trials | Publisher |
|---|---|---|---|
| Dietary vitamin B9 intake linked to drug-resistant epilepsy risk in western Chinese adults: exploring underlying metabolomic mechanisms. | Zhang L, Liu L. | Front Nutr. 2025 Dec 19;12:1723304. doi: 10.3389/fnut.2025.1723304. eCollection 2025. | PMID: 41487671 Free PMC article. |
| The ketogenic diet is not for everyone: contraindications, side effects, and drug interactions. | Dyńka D, Rodzeń Ł, Rodzeń M, Łojko D, Karakuła-Juchnowicz H, Ede G, Grzywacz Ż, Antosik K, Sethi S, Unwin D. | Ann Med. 2026 Dec;58(1):2603016. doi: 10.1080/07853890.2025.2603016. Epub 2026 Jan 4. | PMID: 41486865 Review. |
| Lidocaine as a potential anti-seizure therapy for pediatric FIRES: a promising therapeutic approach. | Yang Y, Wei N, Guan Q, Xie H, Huang X, Ru X, Wu Y, Wang Y, Sang T. | Front Pediatr. 2025 Dec 17;13:1696294. doi: 10.3389/fped.2025.1696294. eCollection 2025. | PMID: 41480377 Free PMC article. |
| The Therapeutic Role of Physical Activity in Epilepsy: Potential Mechanisms and Clinical Implications. | BaoFeng L. | Dev Neurobiol. 2026 Jan;86(1):e70004. doi: 10.1002/dneu.70004. | PMID: 41476274 Review. |
| Medically supervised ketogenic diet as an adjunctive treatment for moderate to severe depression: A pilot study. | Brietzke E, Fabe J, Bambokian A, Breda V, Chaves C, Shelp J, Terpstra A, Koning E, Groll D, Milev R, McIntyre RS, Mansur RB, Soares CN, Gomes FA. | J Affect Disord. 2025 Dec 29:121079. doi: 10.1016/j.jad.2025.121079. Online ahead of print. | PMID: 41475571 |
| Elevated cerebrospinal fluid 2-Hydroxybutyric acid in two siblings with aspartate-glutamate carrier 1 deficiency. | Urquiza N, Partikian A, Bluml S, Saitsu H, Matsumoto N, Griffith LW, McGowan R, Yano S. | Mol Genet Metab. 2025 Dec 27;147(1):109712. doi: 10.1016/j.ymgme.2025.109712. Online ahead of print. | PMID: 41475179 |
| Nutrition and Physical Activity in an Interdisciplinary Approach to Migraine: A Narrative Review. | Pippi R, Prete D, Alabiso M, Sarchielli P. | Nutrients. 2025 Dec 11;17(24):3869. doi: 10.3390/nu17243869. | PMID: 41470814 Free PMC article. Review. |
| Impact of Dietary Patterns on Skeletal Health: A Systematic Review and Meta-Analysis of Bone Mineral Density, Fracture, Bone Turnover Markers, and Nutritional Status. | Mullath Ullas A, Boamah J, Hussain A, Myrtziou I, Kanakis I. | Nutrients. 2025 Dec 9;17(24):3845. doi: 10.3390/nu17243845. | PMID: 41470790 Free PMC article. Review. |
| Infantile Spasms (West Syndrome): Integrating Genetic, Neurotrophic, and Hormonal Mechanisms Toward Precision Therapy. | Abdygalyk B, Rabandiyarov M, Lepessova M, Koshkimbayeva G, Zharkinbekova N, Tekebayeva L, Zhailganov A, Issabekova A, Myrzaliyeva B, Tulendiyeva A, Kurmantay A, Turmanbetova A, Yerkenova S. | Medicina (Kaunas). 2025 Dec 16;61(12):2223. doi: 10.3390/medicina61122223. | PMID: 41470225 Free PMC article. Review. |
| Gut microbiota signatures associated with ketogenic diet response in pediatric drug-resistant epilepsy. | Wang Y, Guo J, Zhang P, Zhou Q, Peng K, Xu Z, Dong X, Ye J, Li H. | Seizure. 2025 Dec 23;134:220-228. doi: 10.1016/j.seizure.2025.12.012. Online ahead of print. | PMID: 41468651 |
| Ketogenic Diet Therapy for Adult Febrile Infection-Related Epilepsy Syndrome (FIRES): A Case Series of Five Patients and Clinical Efficacy Analysis. | Fan M, Li Y, Diao H, Wang Y. | Infect Drug Resist. 2025 Dec 24;18:6875-6888. doi: 10.2147/IDR.S574683. eCollection 2025. | PMID: 41466766 Free PMC article. |
| Putative Role of Fatty Acid Metabolic Therapy Using Ketogenic Diet and HIF-1α Inhibition in Hepatocellular Carcinoma: Evidence from an In Vitro Study. | Kimura N, Kitajima Y, Higure K, Matsufuji S, Ikeda S, Furukawa S, Yukimoto K, Tanaka T, Noshiro H. | Int J Mol Sci. 2025 Dec 5;26(24):11769. doi: 10.3390/ijms262411769. | PMID: 41465202 Free PMC article. |
| Short-term effect of Ketogenic diet and Low-calorie diet on Ketometabolism and lipid metabolism. | Bahrami F, Buetler E, Freiburghaus K, Seubnooch P, Bally L, Maurer J, Flück CE, Wiest R, Masoodi M. | J Nutr Biochem. 2026 Mar;149:110188. doi: 10.1016/j.jnutbio.2025.110188. Epub 2025 Nov 18. | PMID: 41265582 |
| Toward a working definition of ketogenic diet resistance in GLUT1 deficiency syndrome. | Falsaperla R, Sortino V, Kluger GJ, Herberhold T, Rüegger A, Striano P, Ruggieri M, Klepper J, Ramantani G. | Epileptic Disord. 2025 Dec;27(6):1247-1254. doi: 10.1002/epd2.70107. Epub 2025 Sep 30. | PMID: 41026139 Free PMC article. Review. |
| Classic or classical ketogenic diet? Definitions and nomenclature. | RamachandranNair R, Stafstrom CE, Kossoff EH. | Epileptic Disord. 2025 Dec;27(6):1303-1306. doi: 10.1002/epd2.70093. Epub 2025 Aug 29. PMID: 40878448 Free | PMC article. Review. |
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